Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Klaas J. Wardenaar"'
Autor:
Jurriaan M. J. L. Brouwer, Klaas J. Wardenaar, Ilja M. Nolte, Edith J. Liemburg, Pierre M. Bet, Harold Snieder, Hans Mulder, Danielle C. Cath, Brenda W. J. H. Penninx
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Tailoring antidepressant drugs (AD) to patients’ genetic drug-metabolism profile is promising. However, literature regarding associations of ADs’ treatment effect and/or side effects with drug metabolizing genes CYP2D6 and CYP
Externí odkaz:
https://doaj.org/article/61fa815c9a504b8985aa02bad90433c4
Autor:
David Wedema, Klaas J. Wardenaar, Manna A. Alma, Antoinette D. I. van Asselt, Eliza L. Korevaar, Robert A. Schoevers
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Despite the availability of a wide variety of evidence-based treatments for major depressive disorder (MDD), many patients still experience impairments in their lives after remission. Programs are needed that effectively support p
Externí odkaz:
https://doaj.org/article/e67da033d722483790f379292d954e70
Autor:
Celien Tigchelaar, Willemien D. Muller, Sawal D. Atmosoerodjo, Klaas J. Wardenaar, Ido P. Kema, Anthony R. Absalom, Martijn van Faassen
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Potential biomarkers for neuropsychiatric disorders are cerebrospinal fluid (CSF) monoamines and their corresponding precursors and metabolites. During CSF sampling, CSF flows towards the lumbar sampling site from more cranial reg
Externí odkaz:
https://doaj.org/article/f67de4189e8d4edeb469fc6fb6336b28
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Loneliness is associated with major depressive disorder (MDD), and likely also with generalized anxiety disorder (GAD). It is unclear if these associations are moderated by age, sex, or genetic susceptibility for MDD. We included 75,279 indi
Externí odkaz:
https://doaj.org/article/ae4b322ffd4149909883f7eb358d540b
Autor:
David Wedema, Joanieke Siero, Eliza L. Korevaar, Klaas J. Wardenaar, Manna A. Alma, Robert A. Schoevers
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Because major depressive disorder (MDD) has a strong negative impact on patients' lives, well–designed treatment programs are needed that address the lasting effects of MDD. Previous work has shown that such programs should not only focus on sympto
Externí odkaz:
https://doaj.org/article/2704a80f63224c1fad930b867245ab0b
Autor:
Sally A. Mayle, Jessica M. de Klerk-Sluis, Ashleigh Lin, Alison R. Yung, Klaas J. Wardenaar, Sanne R J Broekman, W Heleen Pluim, Johanna T. W. Wigman
Publikováno v:
Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background The Multidimensional Adolescent Functioning Scale (MAFS) is a 23-item, self-report questionnaire assessing psychosocial functioning in adolescents aged 12–17 years. It captures three domains of functioning: ‘general functionin
Externí odkaz:
https://doaj.org/article/a1eb63ce701b4ea891c04d08b367c7f7
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Little is known about the public stigma on mental illness and mental health knowledge (MHK) in China, public stigma and low MHK can negatively affect patients’ health and increase the burden of mental disorders on society. This
Externí odkaz:
https://doaj.org/article/ffef1c63572f4807a54d2f1f7a70c223
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Failure to seek treatment for mental health disorders is a serious public health concern. Unfortunately, there is little insight into help-seeking and its associated factors in China which has undergone rapid economic development
Externí odkaz:
https://doaj.org/article/1d7e3bd1c1644efab333df2e25ac0d92
Autor:
Roelof B. Toonen, Klaas J. Wardenaar, Elisabeth H. Bos, Sonja L. van Ockenburg, Peter de Jonge
Publikováno v:
BMC Medical Research Methodology, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, w
Externí odkaz:
https://doaj.org/article/5f5b6c838b7e495fb146b776e5eff478
Autor:
Jenny Borkent, Magdalini Ioannou, Tessa S. Folkertsma, Klaas J. Wardenaar, Bartholomeus C.M. Haarman, Harry van Goor, Iris E.C. Sommer, Arno R. Bourgonje
Publikováno v:
Psychiatry Research, 321:115075. ELSEVIER IRELAND LTD
Schizophrenia spectrum disorders (SSD) have been linked to oxidative stress (OS). Recent findings from our group show that serum free thiols (R-SH, sulfhydryl groups) can function as an accurate biomarker of systemic OS, since they are readily oxidiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe27d6a050a72e56923349dc91ab04fc
https://research.rug.nl/en/publications/6edc8540-6bd0-4969-aa8f-2b06403799d4
https://research.rug.nl/en/publications/6edc8540-6bd0-4969-aa8f-2b06403799d4
