Výsledky vyhledávání - "Klaas J. Lusthof"

Abortion after deliberate Arthrotec® addition to food. Mass spectrometric detection of diclofenac, misoprostol acid, and their urinary metabolites

Autor: Bernhard Watzer, Klaas J. Lusthof, Horst Schweer

Publikováno v: International Journal of Legal Medicine. 129:759-769

Arthrotec(®) (AT) is a combination of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and misoprostol (MP), a synthetic analogue of prostaglandin E1 (PGE1). MP is a lipophilic methyl ester prodrug. It is readily metabolized to the biologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1de6d6d24e39e8db3c8ca7d3b67c07
https://doi.org/10.1007/s00414-014-1136-4

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Hydrogen peroxide reactions on cocaine in hair using imaging mass spectrometry

Autor: Ingrid J. Bosman, Bryn Flinders, Eva Cuypers, Klaas J. Lusthof, Arian C. van Asten, Jan Tytgat, Ron M. A. Heeren

Publikováno v: Forensic Science International, 242, 103-110. Elsevier Ireland Ltd
Forensic Science International, 242, 103-110. Elsevier

Today, forensic hair analysis is considered to be a standard method for identifying chronic drug users since information about drug use stored and located in hair can cover several months to even years. When interpreting these results, one should be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf3f3777d7ef7cd0c69c02a6a56feac
https://doi.org/10.1016/j.forsciint.2014.06.035

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The relation between the blood benzodiazepine concentration and performance in suspected impaired drivers

Autor: J. de Gier, Donald R. A. Uges, Beitske E. Smink, Antoine C. G. Egberts, Klaas J. Lusthof

Publikováno v: Journal of Forensic and Legal Medicine. 15:483-488

Several experimental studies have shown a negative influence of benzodiazepines on driving skills. The objective of this study is to study the relationship between the blood concentration of benzodiazepines and the influence on performance in field s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0af66bc0497b92457ed510a51778859
https://doi.org/10.1016/j.jflm.2008.04.002

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The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30 mg oxazepam

Autor: Albert Dijkhuizen, Klaas J. Lusthof, Donald R. A. Uges, Antoine C. G. Egberts, Beitske E. Smink, Johan J. de Gier, Berendina J. A. Hofman

Publikováno v: British Journal of Clinical Pharmacology, 66(4), 556-560. Wiley

AIMSTo measure and compare the concentration-time profiles of oxazepam and oxazepam glucuronide in blood, serum and oral fluid within the scope of roadside testing.METHODSBiological samples were collected from eight male subjects after ingestion of 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981b1b9a36a419bd0ce374631428f52a
https://doi.org/10.1111/j.1365-2125.2008.03252.x

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Post-mortem cases involving amphetamine-based drugs in the Netherlands

Autor: Beitske E. Smink, Klaas J. Lusthof, Bart Ruiter, Ingrid J. Bosman, Miranda Verschraagen, A. Maes

Publikováno v: Forensic Science International. 170:163-170

In this study we reviewed the post-mortem cases in the years 1999-2004 that were presented at the Netherlands Forensic Institute. The concentrations of amphetamine-based drugs in femoral blood from cases of suspected unnatural death were compared wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c77ad63c6cb42579e954d43eab1636c0
https://doi.org/10.1016/j.forsciint.2007.03.030

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Drug use and the severity of a traffic accident

Autor: J. de Gier, Donald R. A. Uges, Beitske E. Smink, Bart Ruiter, Klaas J. Lusthof, Antoine C. G. Egberts

Publikováno v: Accident Analysis and Prevention, 37(3), 427-433. PERGAMON-ELSEVIER SCIENCE LTD

Several studies have showed that driving under the influence of alcohol and/or certain illicit or medicinal drugs increases the risk of a (severe) crash. Data with respect to the question whether this also leads to a more severe accident are sparse.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9395b30bbe1b9bacdcfabbdbd129ed
https://doi.org/10.1016/j.aap.2004.12.003

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Quantitative analysis of 33 benzodiazepines, metabolites and benzodiazepine-like substances in whole blood by liquid chromatography–(tandem) mass spectrometry

Autor: Klaas J. Lusthof, Albert Dijkhuizen, Antoine C. G. Egberts, Donald R. A. Uges, J.E. Brandsma, J. De Gier, Beitske E. Smink

Publikováno v: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 811(1), 13-20. ELSEVIER SCIENCE BV

A quantitative method using high-performance liquid chromatography–mass spectrometry (LC–MS, ion trap) after matrix supported liquid–liquid extraction is described for the simultaneous determination in whole blood of 33 benzodiazepines includin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6376bf7012059429397416669c28f3ce
https://doi.org/10.1016/s1570-0232(04)00640-3

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Forensic cases involving the use of GHB in The Netherlands

Autor: Ingrid J. Bosman, Klaas J. Lusthof

Publikováno v: Forensic Science International. 133:17-21

In this study, forensic cases involving the use of Gamma Hydroxy Butyric acid (GHB) from the second half of 1999 through the second half of 2001 in The Netherlands (blood >5 mg/l and urine >10 mg/l) are described. GHB was analysed by GC–MS after la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cf960ba6d0a8ae25deff7ae9f3f749
https://doi.org/10.1016/s0379-0738(03)00044-6

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A case of extreme agitation and death after the use of mephedrone in The Netherlands

Autor: Klaas J. Lusthof, A. Maes, Miranda Verschraagen, Annette Sprong, Roelof Oosting, Albert Dijkhuizen

Publikováno v: Forensic Science International. 206:e93-e95

A 36-year old man, having injured himself severely by smashing windows in a rage of fury, was arrested by the police. He died despite resuscitation attempts. The forensic autopsy showed many superficial skin lacerations, bruises and minor brain swell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e599932bf50ebeb38920453b325557
https://doi.org/10.1016/j.forsciint.2010.12.014

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Use of Clonidine for Chemical Submission

Autor: Klaas J. Lusthof, Peter G.M. Zweipfenning, Wubbo Lameijer

Publikováno v: Journal of Toxicology: Clinical Toxicology. 38:329-332

Case Report: An East-European prostitute in Amsterdam robbed several victims, after having sedated them with clonidine solution (available as plastic ampoules of eyedrops) added to her victims' drinks. One victim was hospitalized. His symptoms includ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53d5b7d8ecdc4ed0f71f4458d859d72
https://doi.org/10.1081/clt-100100940

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