Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Klaas Hallenga"'
Publikováno v:
Journal of Biomolecular NMR. 39:177-185
We present a highly sensitive pulse sequence, carbonyl carbon label selective (1)H-(15)N HSQC (CCLS-HSQC) for the detection of signals from (1)H-(15)N units involved in (13)C'-(15)N linkages. The CCLS-HSQC pulse sequence utilizes a modified (15)N CT
Autor:
Changsheng Zhang, John L. Markley, Shanteri Singh, Byron R. Griffith, Min S. Lee, Martin H. Hager, Jon S. Thorson, Klaas Hallenga
Publikováno v:
ACS Chemical Biology. 1:451-460
The recent discovery of the first "self-sacrifice" mechanism for bacterial resistance to the enediyne antitumor antibiotics, where enediyne-induced proteolysis of the resistance protein CalC inactivates both the highly reactive metabolite and the res
Publikováno v:
Protein Science. 14:2515-2525
Eukaryotic low-molecular-weight protein tyrosine phosphatases (LMW PTPs) contain a conserved serine, a histidine with an elevated pKa, and an active site asparagine that together form a highly conserved hydrogen bonding network. This network stabiliz
Publikováno v:
Journal of the American Chemical Society. 127:12528-12536
We describe a novel approach to the rapid collection and processing of multidimensional NMR data: "high-resolution iterative frequency identification for NMR" (HIFI-NMR). As with other reduced dimensionality approaches, HIFI-NMR collects n-dimensiona
Autor:
Hicham Fenniri, Pappannan Thiyagarajan, Klaas Hallenga, Alexander E. Ribbe, Bo-Liang Deng, Jaby Jacob
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6487-6492
Rosette nanotubes are a new class of organic nanotubes obtained through the hierarchical self-assembly of low molecular weight synthetic modules in water. Here we demonstrate that these materials can serve as scaffolds for the supramolecular synthesi
Autor:
Michael A. Weiss, Qing Xin Hua, Andrzej Joachimiak, Klaas Hallenga, Martin A. Walsh, Irina Dementieva
Publikováno v:
Journal of Molecular Biology. 306:513-525
A homologue of the Escherichia coli GroEL apical domain was obtained from thermophilic eubacterium Thermus thermophilus. The domains share 70 % sequence identity (101 out of 145 residues). The thermal stability of the T. thermophilus apical domain (T
Autor:
Laura A. Labeots, Ming Zhao, Satoe Nakagawa, Klaas Hallenga, Leila Su, Michael A. Weiss, James T. Radek, Huifen Chen, Steve Kates, Patrick Hermanto
Publikováno v:
Genes & Development. 11:2214-2226
Antitermination protein N regulates the transcriptional program of phage λ through recognition of RNA enhancer elements. Binding of an arginine-rich peptide to one face of an RNA hairpin organizes the other, which in turn binds to the host antitermi
Autor:
Guy Lippens, Klaas Hallenga
Publikováno v:
Journal of Biomolecular NMR. 5:59-66
An improved version of the constant-time HSQC experiment is presented that gives uniform sensitivity over the complete (13)C bandwidth in (13)C-(1)H correlation experiments without creating artifacts in the methyl and aromatic regions of the spectra.
Autor:
Marianne Rooman, Alessandro Pintar, Klaas Hallenga, Alain Chaffotte, Jonathan Knowles, Charles G. Bradshaw, Shoshana J. Wodak, Michel Goldberg, Celine Cadieux, Andre Chollet
Publikováno v:
Biochemistry. 33:11158-11173
Four peptides corresponding to alpha-helical regions delimited by residues 63-73 and 97-112 of cytochrome c2 (Rhodospirillum) and residues 24-36 and 45-55 of bovine calcium binding protein are predicted to be alpha-helical by a recently developed met
Autor:
Alain Segers, Lode Wyns, Venki Ramakrishnan, Corinne Cerf, Klaas Hallenga, Guy Lippens, Serge Muyldermans, Shoshana J. Wodak
Publikováno v:
Biochemistry. 33:11079-11086
The globular domain of chicken histone H1 (GH1) has been studied by 1H homonuclear and 1H-15N heteronuclear 2D NMR spectroscopy. After the full assignment of the proton and 15N resonances, the tertiary structure of GH1 was determined by an iterative