Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Klaartje van Engelen"'
Autor:
Rosa de Groot, Antoinette Hollestelle, Klaartje van Engelen, Muriel A Adank, Marjanka K Schmidt, Marinus J Blok, Frans B L Hogervorst, Johan J P Gille, Lieke P V Berger, Marijke R Wevers, Maartje A.C. Schreurs, Denise J Stommel-Jenner, Christi J. Van Asperen, Margreet G.E.M. Ausems, Willemina Geurts-Giele, Maartje J. Hooning
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Purpose CHEK2 c.1100delC is associated with an increased breast cancer risk in women. While this variant is prevalent in the Netherlands (1% in the general population), knowledge of aetiology and prognosis of breast cancer and other tumours in CHEK2
Externí odkaz:
https://doaj.org/article/12b3376b0c36448f8b0fb3ed4b761bd3
Autor:
Christopher Hakkaart, John F. Pearson, Louise Marquart, Joe Dennis, George A. R. Wiggins, Daniel R. Barnes, Bridget A. Robinson, Peter D. Mace, Kristiina Aittomäki, Irene L. Andrulis, Banu K. Arun, Jacopo Azzollini, Judith Balmaña, Rosa B. Barkardottir, Sami Belhadj, Lieke Berger, Marinus J. Blok, Susanne E. Boonen, Julika Borde, Angela R. Bradbury, Joan Brunet, Saundra S. Buys, Maria A. Caligo, Ian Campbell, Wendy K. Chung, Kathleen B. M. Claes, GEMO Study Collaborators, EMBRACE Collaborators, Marie-Agnès Collonge-Rame, Jackie Cook, Casey Cosgrove, Fergus J. Couch, Mary B. Daly, Sita Dandiker, Rosemarie Davidson, Miguel de la Hoya, Robin de Putter, Capucine Delnatte, Mallika Dhawan, Orland Diez, Yuan Chun Ding, Susan M. Domchek, Alan Donaldson, Jacqueline Eason, Douglas F. Easton, Hans Ehrencrona, Christoph Engel, D. Gareth Evans, Ulrike Faust, Lidia Feliubadaló, Florentia Fostira, Eitan Friedman, Megan Frone, Debra Frost, Judy Garber, Simon A. Gayther, Andrea Gehrig, Paul Gesta, Andrew K. Godwin, David E. Goldgar, Mark H. Greene, Eric Hahnen, Christopher R. Hake, Ute Hamann, Thomas V. O. Hansen, Jan Hauke, Julia Hentschel, Natalie Herold, Ellen Honisch, Peter J. Hulick, Evgeny N. Imyanitov, SWE-BRCA Investigators, kConFab Investigators, HEBON Investigators, Claudine Isaacs, Louise Izatt, Angel Izquierdo, Anna Jakubowska, Paul A. James, Ramunas Janavicius, Esther M. John, Vijai Joseph, Beth Y. Karlan, Zoe Kemp, Judy Kirk, Irene Konstantopoulou, Marco Koudijs, Ava Kwong, Yael Laitman, Fiona Lalloo, Christine Lasset, Charlotte Lautrup, Conxi Lazaro, Clémentine Legrand, Goska Leslie, Fabienne Lesueur, Phuong L. Mai, Siranoush Manoukian, Véronique Mari, John W. M. Martens, Lesley McGuffog, Noura Mebirouk, Alfons Meindl, Austin Miller, Marco Montagna, Lidia Moserle, Emmanuelle Mouret-Fourme, Hannah Musgrave, Sophie Nambot, Katherine L. Nathanson, Susan L. Neuhausen, Heli Nevanlinna, Joanne Ngeow Yuen Yie, Tu Nguyen-Dumont, Liene Nikitina-Zake, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Ana Osorio, Claus-Eric Ott, Sue K. Park, Michael T. Parsons, Inge Sokilde Pedersen, Ana Peixoto, Pedro Perez-Segura, Paolo Peterlongo, Timea Pocza, Paolo Radice, Juliane Ramser, Johanna Rantala, Gustavo C. Rodriguez, Karina Rønlund, Efraim H. Rosenberg, Maria Rossing, Rita K. Schmutzler, Payal D. Shah, Saba Sharif, Priyanka Sharma, Lucy E. Side, Jacques Simard, Christian F. Singer, Katie Snape, Doris Steinemann, Dominique Stoppa-Lyonnet, Christian Sutter, Yen Yen Tan, Manuel R. Teixeira, Soo Hwang Teo, Mads Thomassen, Darcy L. Thull, Marc Tischkowitz, Amanda E. Toland, Alison H. Trainer, Vishakha Tripathi, Nadine Tung, Klaartje van Engelen, Elizabeth J. van Rensburg, Ana Vega, Alessandra Viel, Lisa Walker, Jeffrey N. Weitzel, Marike R. Wevers, Georgia Chenevix-Trench, Amanda B. Spurdle, Antonis C. Antoniou, Logan C. Walker
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The risk of germline copy number variants (CNVs) in BRCA1 and BRCA2 pathogenic variant carriers in breast cancer is assessed, with CNVs overlapping SULT1A1 decreasing breast cancer risk in BRCA1 carriers.
Externí odkaz:
https://doaj.org/article/2008d12983b5437282b0bdff8c8a6bb0
Autor:
Delal Akdeniz, Mark van Barele, Bernadette A.M. Heemskerk-Gerritsen, Ewout W. Steyerberg, Michael Hauptmann, Irma van de Beek, Klaartje van Engelen, Marijke R. Wevers, Encarnacion B. Gómez García, Margreet G.E.M. Ausems, Lieke P.V. Berger, Christi J. van Asperen, Muriel A. Adank, Margriet J. Collée, Denise J. Stommel-Jenner, Agnes Jager, Marjanka K. Schmidt, Maartje J. Hooning
Publikováno v:
Breast, Vol 61, Iss , Pp 98-107 (2022)
Aim: BRCA1/2 mutation carriers with primary breast cancer (PBC) are at high risk of contralateral breast cancer (CBC). In a nationwide cohort, we investigated the effects of chemotherapeutic agents given for PBC on CBC risk separately in BRCA1 and BR
Externí odkaz:
https://doaj.org/article/f07b5cdd82d14cf6b8c51743fa5578cb
Autor:
Jeanine A.M. van der Giessen, Sandra van Dulmen, Mary E. Velthuizen, Maria E.T.C. van den Muijsenbergh, Klaartje van Engelen, Margriet Collée, Thijs van Dalen, Cora M. Aalfs, Maartje J. Hooning, Peter M.M. Spreeuwenberg, Mirjam P. Fransen, Margreet G.E.M. Ausems
Publikováno v:
Breast, Vol 58, Iss , Pp 80-87 (2021)
Background: There is an underuse of genetic testing in breast cancer patients with a lower level of education, limited health literacy or a migrant background. We aimed to study the effect of a health literacy training program for surgical oncologist
Externí odkaz:
https://doaj.org/article/7d747e9df89f4b0e88a5ad1b08b29ba1
Autor:
Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, GENEPSO, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, EMBRACE, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, HEBON, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, kConFab Investigators, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. Van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton, on behalf of IBCCS, kConFab, BCFR
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background The effect of risk-reducing salpingo-oophorectomy (RRSO) on breast cancer risk for BRCA1 and BRCA2 mutation carriers is uncertain. Retrospective analyses have suggested a protective effect but may be substantially biased. Prospect
Externí odkaz:
https://doaj.org/article/d2bd4331f6ac44868c0ed8e56dec068e
Autor:
Bernadette A M Heemskerk-Gerritsen, Antoinette Hollestelle, Christi J van Asperen, Irma van den Beek, Willemien J van Driel, Klaartje van Engelen, Encarna B Gómez Garcia, Joanne A de Hullu, Marco J Koudijs, Marian J E Mourits, Maartje J Hooning, Ingrid A Boere
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275015 (2022)
IntroductionGermline BRCA1/2-associated epithelial ovarian cancer has been associated with better progression-free survival and overall survival than sporadic epithelial ovarian cancer, but conclusive data are lacking.MethodsWe matched 389 BRCA1-asso
Externí odkaz:
https://doaj.org/article/78bf0cb2beca4827a30625f36863fc26
Autor:
Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, GENEPSO, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, EMBRACE, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, HEBON, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, kConFab Investigators, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. Van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton, on behalf of IBCCS, kConFab and BCFR
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-3 (2020)
After publication of the original article [1], we were notified that columns in Table 2 were erroneously displayed.
Externí odkaz:
https://doaj.org/article/209bfc06acbe40aca02aa85e0b80b7ca
Autor:
Hubert Baars, Eline Overwater, Marieke Baars, Barbara Mulder, Wilhelmina Kerstjens-Frederikse, Klaartje van Engelen, Arjan Houweling
Publikováno v:
Cardiogenetics, Vol 5, Iss 1 (2015)
Bicuspid aortic valve (BAV) is the most common congenital cardiac defect causing serious morbidity including valvular dysfunction and thoracic aortic aneurysms (TAA) in around 30% of BAV patients. Cardiological screening of first-degree relatives is
Externí odkaz:
https://doaj.org/article/a3b01313b4474702bfe181eb45aa45f7
Autor:
Klaartje van Engelen, Mathilda T M Mommersteeg, Marieke J H Baars, Jan Lam, Aho Ilgun, A S Paul van Trotsenburg, Anne M J B Smets, Vincent M Christoffels, Barbara J M Mulder, Alex V Postma
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52685 (2012)
NKX2-5 is a homeodomain-containing transcription factor implied in both heart and thyroid development. Numerous mutations in NKX2-5 have been reported in individuals with congenital heart disease (CHD), but recently a select few have been associated
Externí odkaz:
https://doaj.org/article/14e479b9e14f4598ba93b6a9c3e7a1e1
Autor:
Lara Terra, Philippe R. Lee Meeuw Kjoe, Joost A. Agelink van Rentergem, Maarten J. Beekman, Bernadette A. M. Heemskerk‐Gerritsen, Marc van Beurden, Jeanine E. Roeters van Lennep, Helena C. van Doorn, Joanna A. de Hullu, Marian J. E. Mourits, Eleonora B. L. van Dorst, Constantijne H. Mom, Brigitte F. M. Slangen, Katja N. Gaarenstroom, Lizet E. van der Kolk, J. Margriet Collée, Marijke R. Wevers, Margreet G. E. M. Ausems, Klaartje van Engelen, Irma van de Beek, Lieke P. V. Berger, Christi J. van Asperen, Encarna B. Gomez Garcia, Angela H. E. M. Maas, Maartje J. Hooning, Elsken van der Wall, Flora E. van Leeuwen, Sanne B. Schagen
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology, 130(8), 968-977. Wiley-Blackwell Publishing Ltd
BJOG: An International Journal of Obstetrics & Gynaecology, 130(8), 968-977. Wiley Online Library
BJOG : an International Journal of Obstetrics and Gynaecology, 130, 968-977
Bjog-an International Journal of Obstetrics and Gynaecology, 130(8), 968-977. Wiley
BJOG : an International Journal of Obstetrics and Gynaecology, 130, 8, pp. 968-977
Terra, L, Lee Meeuw Kjoe, P R, Agelink van Rentergem, J A, Beekman, M J, Heemskerk-Gerritsen, B A M, van Beurden, M, Roeters van Lennep, J E, van Doorn, H C, de Hullu, J A, Mourits, M J E, van Dorst, E B L, Mom, C H, Slangen, B F M, Gaarenstroom, K N, van der Kolk, L E, Collée, J M, Wevers, M R, Ausems, M G E M, van Engelen, K, van de Beek, I, Berger, L P V, van Asperen, C J, Gomez Garcia, E B, Maas, A H E M, Hooning, M J, van der Wall, E, van Leeuwen, F E & Schagen, S B 2023, ' Long-term effects of premenopausal risk-reducing salpingo-oophorectomy on cognition in women with high familial risk of ovarian cancer : A cross-sectional study ', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 130, no. 8, pp. 968-977 . https://doi.org/10.1111/1471-0528.17415
BJOG: An International Journal of Obstetrics and Gynaecology. Wiley Online Library
BJOG: An International Journal of Obstetrics and Gynaecology. Wiley-Blackwell
BJOG: An International Journal of Obstetrics & Gynaecology, 130(8), 968-977. Wiley Online Library
BJOG : an International Journal of Obstetrics and Gynaecology, 130, 968-977
Bjog-an International Journal of Obstetrics and Gynaecology, 130(8), 968-977. Wiley
BJOG : an International Journal of Obstetrics and Gynaecology, 130, 8, pp. 968-977
Terra, L, Lee Meeuw Kjoe, P R, Agelink van Rentergem, J A, Beekman, M J, Heemskerk-Gerritsen, B A M, van Beurden, M, Roeters van Lennep, J E, van Doorn, H C, de Hullu, J A, Mourits, M J E, van Dorst, E B L, Mom, C H, Slangen, B F M, Gaarenstroom, K N, van der Kolk, L E, Collée, J M, Wevers, M R, Ausems, M G E M, van Engelen, K, van de Beek, I, Berger, L P V, van Asperen, C J, Gomez Garcia, E B, Maas, A H E M, Hooning, M J, van der Wall, E, van Leeuwen, F E & Schagen, S B 2023, ' Long-term effects of premenopausal risk-reducing salpingo-oophorectomy on cognition in women with high familial risk of ovarian cancer : A cross-sectional study ', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 130, no. 8, pp. 968-977 . https://doi.org/10.1111/1471-0528.17415
BJOG: An International Journal of Obstetrics and Gynaecology. Wiley Online Library
BJOG: An International Journal of Obstetrics and Gynaecology. Wiley-Blackwell
Objective: To examine the effect of a premenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at increased risk of ovarian cancer on objective and subjective cognition at least 10 years after RRSO.Design: A cross-sectional study with prospe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f6dd6a8e92792537369585589c875a
https://pure.eur.nl/en/publications/2c44b46f-f6af-4ca6-a55b-975340f19a6a
https://pure.eur.nl/en/publications/2c44b46f-f6af-4ca6-a55b-975340f19a6a
