Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Klöting, Nora"'
Lipedema may be considered a model for healthy expandability of subcutaneous adipose tissue (SAT). This condition is characterized by the disproportional and symmetrical SAT accumulation in the lower-body parts and extremities, avoiding the abdominal
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https://ul.qucosa.de/id/qucosa%3A92958
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Autor:
Kosacka, Joanna, Berger, Claudia, Ceglarek, Uta, Hoffmann, Anne, Blüher, Matthias, Klöting, Nora
The angiotensin-converting enzyme 2 (ACE2) receptor has been identified as the entry receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is abundantly expressed in many organs. With respect to the role of circulating AC
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85944
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Autor:
Klöting, Nora, Schwarzer, Michael, Heyne, Estelle, Ceglarek, Uta, Hoffmann, Anne, Krohn, Knut, Doenst, Torsten, Blüher, Matthias
Angiotensin-converting enzyme 2 (ACE2) has been identified as the cellular entry receptor for the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). High ACE2 tissue expression and low glycine levels were suggested to increase suscep
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A87525
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Autor:
Berger, Claudia, Heyne, Henrike O., Heiland, Tina, Dommel, Sebastian, Höfling, Corinna, Guiu-Jurado, Esther, Lorenz, Jana, Roßner, Steffen, Dannemann, Michael, Kelso, Janet, Kovacs, Peter, Blüher, Matthias, Klöting, Nora
The leptin receptor (Lepr) pathway is important for food intake regulation, energy expenditure, and body weight. Mutations in leptin and the Lepr have been shown to cause early-onset severe obesity in mice and humans. In studies with C57BL/6NCrl mice
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93691
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Autor:
Berger, Claudia, Klöting, Nora
Leptin and its receptor are essential for regulating food intake, energy expenditure, glucose homeostasis and fertility. Mutations within leptin or the leptin receptor cause early-onset obesity and hyperphagia, as described in human and animal models
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A89851
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Autor:
Baum, Petra, Koj, Severin, Klöting, Nora, Blüher, Matthias, Classen, Joseph, Paeschke, Sabine, Gericke, Martin, Toyka, Klaus V., Nowicki, Marcin, Kosacka, Joanna
Treatment-induced neuropathy in diabetes (TIND) is defined by the occurrence of an acute neuropathy within 8 weeks of an abrupt decrease in glycated hemoglobin-A1c (HbA1c). The underlying pathogenic mechanisms are still incompletely understood with o
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A89635
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Autor:
Dommel, Sebastian, Hoffmann, Anne, Berger, Claudia, Kern, Matthias, Klöting, Nora, Kannt, Aimo, Blüher, Matthias
Genome-wide association studies have identified adenylyl cyclase type 5 (ADCY5) as candidate gene for diabetes-related quantitative traits and an increased risk of type 2 diabetes. Mice with a whole-body deletion of Adcy5 (Adcy5–/–) do not develo
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A89409
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Autor:
Zieger, Konstanze, Weiner, Juliane, Kunath, Anne, Gericke, Martin, Krause, Kerstin, Kern, Matthias, Stumvoll, Michael, Klöting, Nora, Blüher, Matthias, Heiker, John T.
Vaspin is an adipokine which improves glucose metabolism and insulin sensitivity in obesity. Kallikrein 7 (KLK7) is the first known protease target inhibited by vaspin and a potential target for the treatment of metabolic disorders. Here, we tested t
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A33207
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Autor:
Klöting, Nora, Hesselbarth, Nico, Gericke, Martin, Kunath, Anne, Biemann, Ronald, Chakaroun, Rima, Kosacka, Joanna, Kovacs, Peter, Kern, Matthias, Stumvoll, Michael, Fischer, Bernd, Rolle-Kampczyk, Ulrike, Feltens, Ralph, Otto, Wolfgang, Wissenbach, Dirk K., von Bergen, Martin, Blüher, Matthias
Publikováno v:
PLoS one 10(12) : e0143190
Di-(2-ethylhexyl)-phthalate (DEHP), an ubiquitous environmental contaminant, has been shown to cause adverse effects on glucose homeostasis and insulin sensitivity in epidemiological studies, but the underlying mechanisms are still unknown. We theref
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A14511
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https://ul.qucosa.de/api/qucosa%3A14511/attachment/ATT-0/
Autor:
Mardinoglu, Adil, Heiker, John T., Gärtner, Daniel, Björnson, Elias, Schön, Michael R., Flehmig, Gesine, Klöting, Nora, Krohn, Knut, Fasshauer, Mathias, Stumvoll, Michael, Nielsen, Jens, Blüher, Matthias
Publikováno v:
Scientific reports 2015, 5:14841
Weight loss has been shown to significantly improve Adipose tissue (AT) function, however changes in AT gene expression profiles particularly in visceral AT (VAT) have not been systematically studied. Here, we tested the hypothesis that extensive wei
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A13938
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