High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis

Autor: Klára Prajzlerová, Olga Kryštůfková, Petra Hánová, Veronika Horváthová, Monika Gregová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt, Mária Filková

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Individuals carrying anti-citrullinated protein antibodies (ACPA) are considered at high risk of developing rheumatoid arthritis (RA). The altered expression of miRNAs contributes to the pathogenesis of RA. We aimed to identify differentiall

Externí odkaz: https://doaj.org/article/34a12d51cbab4668bad29802f3f1eafb

Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis

Autor: Lucie Andrés Cerezo, Barbora Šumová, Klára Prajzlerová, David Veigl, Dres Damgaard, Claus Henrik Nielsen, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt

Publikováno v: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)

Abstract Background Calgizzarin (S100A11) is a member of the S100 protein family that acts in different tumors by regulating a number of biologic functions. Recent data suggest its association with low-grade inflammation in osteoarthritis (OA). The a

Externí odkaz: https://doaj.org/article/b38982b3128a43f7945dcf2b1b2a2ac8

High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis

Autor: Mária Filková, Olga Kryštůfková, Veronika Horváthová, Karel Pavelka, Jiří Vencovský, Monika Gregova, Klára Prajzlerová, Petra Hanova, Ladislav Šenolt

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports

Individuals carrying anti-citrullinated protein antibodies (ACPA) are considered at high risk of developing rheumatoid arthritis (RA). The altered expression of miRNAs contributes to the pathogenesis of RA. We aimed to identify differentially express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3575eeed978ab5e1c38bc9acf34be5b1
https://doaj.org/article/34a12d51cbab4668bad29802f3f1eafb

Elevated Tenascin-C Serum Levels in Patients With Axial Spondyloarthritis

Autor: Michal Tomcik, Hana Hulejová, K Mintalova, Jiří Vencovský, Klára Prajzlerová, Marketa Husakova, Kristyna Bubova, Mária Filková, Monika Gregová, Karel Pavelka, Šárka Forejtová, Ladislav Šenolt

Publikováno v: Physiol Res

This study aimed to examine serum tenascin C (TNC) in different subsets of axial spondyloarthritis (axSpA) patients. Sixty-one patients fulfilling the Assessment of SpondyloArthritis international Society classification criteria for axSpA and 20 heal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b92d589531a653bca58581736a52a2
https://pubmed.ncbi.nlm.nih.gov/32584134

S100A4 is elevated in axial spondyloarthritis:a potential link to disease severity

Autor: Kristýna Bubová, Lucie Andrés Cerezo, Jiří Vencovský, Hana Hulejová, J.J. Štěpán, Barbora Šumová, Karel Pavelka, Mária Filková, Mariam Grigorian, Tereza Kropáčková, Ladislav Šenolt, Michal Tomcik, Klára Prajzlerová

Publikováno v: Sumova, B, Cerezo, L A, Hulejova, H, Prajzlerova, K, Tomcik, M, Bubova, K, Stepan, J, Filkova, M, Kropackova, T, Grigorian, M, Pavelka, K, Vencovsky, J & Senolt, L 2020, ' S100A4 is elevated in axial spondyloarthritis : a potential link to disease severity ', BMC Rheumatology, vol. 4, no. 1, 13 . https://doi.org/10.1186/s41927-019-0110-7
BMC Rheumatology, Vol 4, Iss 1, Pp 1-6 (2020)
BMC Rheumatology

Background S100A4 is a member of calcium binding S100 protein family well known for its role in cancer progression and metastasis. Nevertheless, S100A4 also serves as a negative regulator of bone formation. Dickkopf-1 (DKK-1), marker of bone remodell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b80be994d64a35be980246c9839c6c
https://curis.ku.dk/ws/files/269792892/S100A4_is_elevated_in_axial_spondyloarthritis.pdf