Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Klára Briknarová"'
Autor:
Keshia M. Kerchner, Tung-Chung Mou, Yizhi Sun, Domniţa-Valeria Rusnac, Stephen R. Sprang, Klára Briknarová
Publikováno v:
Journal of Structural Biology: X, Vol 5, Iss , Pp 100050- (2021)
Euchromatic histone-lysine N-methyltransferase 1 (EHMT1; G9a-like protein; GLP) and euchromatic histone-lysine N-methyltransferase 2 (EHMT2; G9a) are protein lysine methyltransferases that regulate gene expression and are essential for development an
Externí odkaz:
https://doaj.org/article/31ace5596d2b4bfd8ba11c38db17413e
Autor:
Celestine J Thomas, Klára Briknarová, Jonathan K Hilmer, Navid Movahed, Brian Bothner, John P Sumida, Gregory G Tall, Stephen R Sprang
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23197 (2011)
Heterotrimeric G protein α subunits are activated upon exchange of GDP for GTP at the nucleotide binding site of Gα, catalyzed by guanine nucleotide exchange factors (GEFs). In addition to transmembrane G protein-coupled receptors (GPCRs), which ac
Externí odkaz:
https://doaj.org/article/8e8b8b682bd141db9e6d1bb49efc6327
Autor:
Dustin C. Becht, Moses J. Leavens, Baisen Zeng, Michael T. Rothfuss, Klára Briknarová, Bruce E. Bowler
Publikováno v:
Biochemistry
The structure of the first ubiquitin-associated domain from HHR23A, UBA(1), was determined by X-ray crystallography at 1.60 Å resolution, and its stability, folding kinetics and residual structure under denaturing conditions have been investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62928f47992598c10b4aecebb07913c
https://europepmc.org/articles/PMC9150713/
https://europepmc.org/articles/PMC9150713/
Autor:
Domniţa-Valeria Rusnac, Keshia M. Kerchner, Klára Briknarová, Stephen R. Sprang, Tung-Chung Mou, Yizhi Sun
Publikováno v:
Journal of Structural Biology: X, Vol 5, Iss, Pp 100050-(2021)
Journal of Structural Biology: X
Journal of Structural Biology: X
Graphical abstract
Highlights • EHMT1/2 histone lysine methyltransferases contain a unique cysteine-rich region (CRR). • The structure of the CRR from human EHMT2 was determined by X-ray crystallography. • The CRR adopts an unusual compact
Highlights • EHMT1/2 histone lysine methyltransferases contain a unique cysteine-rich region (CRR). • The structure of the CRR from human EHMT2 was determined by X-ray crystallography. • The CRR adopts an unusual compact
Autor:
Gabriel J. H. Ahl, Jessica M. Stine, Domnita-Valeria Rusnac, Klára Briknarová, Casey Schlenker
Publikováno v:
Biochemistry. 56:4667-4675
Anastellin is a small recombinant fragment derived from the extracellular matrix protein fibronectin; it comprises the first type III (FN3) domain without the two N-terminal β-strands. It inhibits angiogenesis, tumor growth, and metastasis in mouse
Publikováno v:
Biochemistry. 54:6724-6733
Fibronectin is a modular extracellular matrix protein that is essential for vertebrate development. The third type III domain (3FN3) in fibronectin interacts with other parts of fibronectin and with anastellin, a protein fragment that causes fibronec
Publikováno v:
Biochemistry. 56(51)
There is considerable evidence that long-range interactions stabilize residual protein structure under denaturing conditions. However, evaluation of the effect of a specific contact on structure in the denatured state has been difficult. Iso-1-cytoch
Autor:
J.B. Alexander Ross, Daniel Z. Atwater, Yizhi Sun, Klára Briknarová, Ayesha Sharmin, Jessica M. Stine
Publikováno v:
Biochemistry. 54:1390-1400
RIZ (retinoblastoma protein-interacting zinc finger protein), also denoted PRDM2, is a transcriptional regulator and tumor suppressor. It was initially identified because of its ability to interact with another well-established tumor suppressor, the
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 79:2341-2345
Publikováno v:
Journal of Biological Chemistry. 286:1528-1536
Arenaviruses cause acute hemorrhagic fevers with high mortality. Entry of the virus into the host cell is mediated by the viral envelope glycoprotein, GPC. In contrast to other class I viral envelope glycoproteins, the mature GPC complex contains a c