Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Klára Ács"'
Autor:
Laura K. Herzog, Klára Ács, Annika Pfeiffer, Martijn S. Luijsterburg, Claudia Böttcher, Florian A. Salomons, Angela Helfricht, Haico van Attikum, Nico P. Dantuma, Melania Minoia, Wouter W. Wiegant
Publikováno v:
The EMBO Journal. 36:1066-1083
The SUMO‐targeted ubiquitin ligase RNF4 functions at the crossroads of the SUMO and ubiquitin systems. Here, we report that the deubiquitylation enzyme (DUB) ataxin‐3 counteracts RNF4 activity during the DNA double‐strand break (DSB) response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbde393ffb7b9c14804170b7e4baf3f3
https://doi.org/10.15252/embj.201695151
https://doi.org/10.15252/embj.201695151
Autor:
Juho Miettinen, Philipp Sergeev, Sadiksha Adhikari, Maiju-Emilia Huppunen, Minna Suvela, Ana Slipicevic, Nina N Nupponen, Klara Acs, Fredrik Lehmann, Caroline Heckman
Publikováno v:
HemaSphere, Vol 7, p e9358540 (2023)
Externí odkaz:
https://doaj.org/article/b5e07e40eb0946358c2f67ca8dcfbc15
Autor:
Wouter W. Wiegant, Kum Kum Khanna, Simon Bekker-Jensen, Leena Ackermann, Haico van Attikum, Martijn S. Luijsterburg, Nico P. Dantuma, Niels Mailand, Klára Ács, Dorthe Helena Larsen
Publikováno v:
The EMBO Journal. 31:2511-2527
The ubiquitin ligases RNF8 and RNF168 orchestrate DNA damage signalling through the ubiquitylation of histone H2A and the recruitment of downstream repair factors. Here, we demonstrate that RNF8, but not RNF168 or the canonical H2A ubiquitin ligase R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5908c3c108805affe5b999b63d4cbdbf
https://doi.org/10.1038/emboj.2012.104
https://doi.org/10.1038/emboj.2012.104
Autor:
Martijn S. Luijsterburg, Klára Ács, Nico P. Dantuma, Florian A. Salomons, Thorsten Hoppe, Leena Ackermann
Publikováno v:
Nature Structural & Molecular Biology. 18:1345-1350
The accumulation of the human tumor suppressor 53BP1 at DNA damage sites requires the ubiquitin ligases RNF8 and RNF168. As 53BP1 recognizes dimethylated Lys20 in histone H4 (H4K20me2), the requirement for RNF8- and RNF168-mediated ubiquitylation has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28897a924856a48835225073f72a2e0
https://doi.org/10.1038/nsmb.2188
https://doi.org/10.1038/nsmb.2188
Publikováno v:
Experimental Cell Research. 316:1289-1295
The ubiquitin/proteasome system (UPS) is responsible for the regulated processive degradation of proteins residing in the cytosol, nucleus, and endoplasmic reticulum. The two central players are ubiquitin, a small protein that is conjugated to substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f3c2ff2606e4fabf454c828c78457e
https://doi.org/10.1016/j.yexcr.2010.02.003
https://doi.org/10.1016/j.yexcr.2010.02.003
Autor:
Klára Ács, Kathleen A. Martin, Karen Douville, Robert J. Wagner, Min Ding, Kristina M. Fetalvero, Zsolt Kasza, Richard J. Powell, John Hwa, Anthony K. Guzman
Publikováno v:
Journal of Molecular and Cellular Cardiology. 46:682-694
The important athero-protective role of prostacyclin is becoming increasingly evident as recent studies have revealed adverse cardiovascular effects in mice lacking the prostacyclin receptor, in patients taking selective COX-2 inhibitors, and in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747936b49812511c550ff0eb6533b7f3
https://doi.org/10.1016/j.yjmcc.2009.01.006
https://doi.org/10.1016/j.yjmcc.2009.01.006
Publikováno v:
Experimental Cell Research, 329(1), 9-17
The ordered assembly of DNA repair factors on chromatin has been studied in great detail, whereas we are only beginning to realize that selective extraction of proteins from chromatin plays a central role in the DNA damage response. Interestingly, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2719d7ec0e51814cc1a1959549baf60
https://pubmed.ncbi.nlm.nih.gov/25169698
https://pubmed.ncbi.nlm.nih.gov/25169698
Publikováno v:
Acta Biologica Hungarica. 52:365-373
Mucor genevensis is a dimorphic and homothallic fungal species (Zygomycetes). Ten M. genevensis strains, each strain of the recently described new homothallic species (M. meguroense and M. hachijyoensis) and strains of M. hiemalis and M. piriformis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b53092664ebbdb71525c8f8cd414d6d
https://doi.org/10.1556/abiol.52.2001.2-3.21
https://doi.org/10.1556/abiol.52.2001.2-3.21
Publikováno v:
Acta Microbiologica et Immunologica Hungarica. 48:153-286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65fd53131f585048dd39777cd0942513
https://doi.org/10.1556/amicr.48.2001.2.2
https://doi.org/10.1556/amicr.48.2001.2.2
Publikováno v:
Mycological Research. 103:1318-1322
To test the validity of R. tauricus as a separate species, its carbon source utilization, isoenzyme patterns and PCR-coupled RFLP of the ITS of its rDNA were analysed. Whilst R. tauricus differed considerably from R. pusillus and R. miehei in morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::538a2f13369a994bf3a72c34319c1d3d
https://doi.org/10.1017/s0953756298008508
https://doi.org/10.1017/s0953756298008508