A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

Autor: Aa, Al Olama, Kote-Jarai Z, Si, Berndt, Dv, Conti, Schumacher F, Han Y, Benlloch S, Dj, Hazelett, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, Do, Stram, Rand K, Wan P, Stram A, Sheng X, Lc, Pooler, Park K, Xia L, Tyrer J, Ln, Kolonel, Le Marchand L, Rn, Hoover, Mj, Machiela, Yeager M, Burdette L, Cc, Chung, Hutchinson A, Yu K, Goh C, Ahmed M, Govindasami K, Guy M, Tl, Tammela, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, Ka, Leinonen, Xu J, Aly M, Donovan J, Rc, Travis, Tj, Key, Siddiq A, Canzian F, Kt, Khaw, Takahashi A, Kubo M, Pharoah P, Pashayan N, Weischer M, Bg, Nordestgaard, Sf, Nielsen, Klarskov P, Ma, Røder, Iversen P, Sn, Thibodeau, Sk, Mcdonnell, Dj, Schaid, Jl, Stanford, Kolb S, Holt S, Knudsen B, Ah, Coll, Sm, Gapstur, Wr, Diver, Vl, Stevens, Maier C, Luedeke M, Herkommer K, Ae, Rinckleb, Ss, Strom, Pettaway C, Ed, Yeboah, Tettey Y, Rb, Biritwum, Aa, Adjei, Tay E, Truelove A, Niwa S, Ap, Chokkalingam, Cannon-Albright L, Cybulski C, Wokołorczyk D, Kluźniak W, Park J, Sellers T, Hy, Lin, Wb, Isaacs, Aw, Partin, Brenner H, Ak, Dieffenbach, Stegmaier C, Chen C, El, Giovannucci, Ma J, Stampfer M, Kl, Penney, Mucci L, Em, John, Sa, Ingles, Ra, Kittles, Ab, Murphy, Pandha H, Michael A, Am, Kierzek, Blot W, Lb, Signorello, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske C, Sy, Wu, Hennis A, As, Kibel, Ba, Rybicki, Neslund-Dudas C, Aw, Hsing, Chu L, Pj, Goodman, Ea, Klein, Sl, Zheng, Batra J, Clements J, Spurdle A, Teixeira MR, Maia S, Slavov C, Kaneva R, Mitev V, Js, Witte, Casey G, Em, Gillanders, Seminara D, Riboli E, Fc, Hamdy, Ga, Coetzee, Li Q, Ml, Freedman, Dj, Hunter, Muir K, Gronberg H, Neal DE, Southey M, Gg, Giles, Severi G, Mb, Cook, Nakagawa H, Wiklund F, Kraft P, Sj, Chanock, Be, Henderson, Df, Easton, Ra, Eeles, Ca, Haiman

Publikováno v: Europe PubMed Central
CIÊNCIAVITAE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aef5347bcf41938155e292d349a08bd4
http://europepmc.org/abstract/med/25217961

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.

Autor: Wu L; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA. lwu@cc.hawaii.edu., Yang Y; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Guo X; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Shu X; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Li B; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Tao R; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Wu C; Department of Statistics, Florida State University, Tallahassee, FL, USA., Nikas JB; Research & Development, Genomix Inc, Minneapolis, MN, USA., Sun Y; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA.; College of Life Science, Longyan University, Longyan, Fujian, P. R. China., Zhu J; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA., Roobol MJ; Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, 207 Bouverie St, Melbourne, VIC, 3010, Australia.; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, 615 St Kilda Rd, Melbourne, VIC, 3004, Australia., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., John EM; Department of Medicine (Oncology) and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA., Clements J; Australian Prostate Cancer Research Centre-QLD, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, QLD, Australia.; Translational Research Institute, Brisbane, QLD, Australia., Grindedal EM; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Park JY; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA., Stanford JL; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA., Kote-Jarai Z; Division of Genetics and Epidemiology, The Institute of Cancer Research, and The Royal Marsden NHS Foundation Trust, London, UK., Haiman CA; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Eeles RA; Division of Genetics and Epidemiology, The Institute of Cancer Research, and The Royal Marsden NHS Foundation Trust, London, UK., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA. jirong.long@vumc.org.

Publikováno v: Nature communications [Nat Commun] 2020 Aug 06; Vol. 11 (1), pp. 3905. Date of Electronic Publication: 2020 Aug 06.

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis.

Autor: Yarmolinsky J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK. Electronic address: j.yarmolinsky@imperial.ac.uk., Robinson JW; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Mariosa D; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Karhunen V; Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Research Unit of Mathematical Sciences, University of Oulu, Oulu, Finland., Huang J; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore., Dimou N; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Murphy N; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Burrows K; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bouras E; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece., Smith-Byrne K; The Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lewis SJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Galesloot TE; Radboud University Medical Center, Nijmegen, The Netherlands., Kiemeney LA; Radboud University Medical Center, Nijmegen, The Netherlands., Vermeulen S; Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands., Martin P; School of Biochemistry, Biomedical Sciences Building, University of Bristol, University Walk, Bristol, UK., Albanes D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Hou L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; School of Public Health, University of Washington, Seattle, WA, USA., White E; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Wu AH; University of Southern California, Preventative Medicine, Los Angeles, CA, USA., Le Marchand L; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA., Phipps AI; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Buchanan DD; Colorectal Oncogenomic Group, Department of Clinical Pathology, University of Melbourne, Parkville, Victoria, Australia; Victorian Comprehensive Cancer Centre, University of Melbourne Centre for Cancer Research, Parkville, Victoria, Australia; Genetic Medicine and Family Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia., Zhao SS; Centre for Epidemiology Versus Arthritis, Faculty of Biological Medicine and Health, University of Manchester, Manchester, UK., Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA., Purdue MP; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA., Davey Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Brennan P; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Herzig KH; Institute of Biomedicine, Medical Research Center and Oulu University Hospital, University of Oulu, Oulu, Finland; Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland., Järvelin MR; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Amos CI; Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA., Hung RJ; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., Dehghan A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK; Dementia Research Institute, Imperial College London, London, UK., Johansson M; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Gunter MJ; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Tsilidis KK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, UK; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece., Martin RM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; University Hospitals Bristol and Weston NHS Foundation Trust, National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, Bristol, UK.

Publikováno v: EBioMedicine [EBioMedicine] 2024 Feb; Vol. 100, pp. 104991. Date of Electronic Publication: 2024 Feb 01.

Lower and Early Middle Palaeolithic of Southern Britain: the Evidence from the River Test.

Autor: Davis, Rob, Ashton, Nick, Hatch, Marcus, Hosfield, Rob, Lewis, Simon G.

Publikováno v: Journal of Paleolithic Archaeology; Sep2021, Vol. 4 Issue 3, p1-50, 50p

Replication of a genetic variant for prostate cancer-specific mortality.

Autor: Penney, K L¹, Shui, I M², Feng, Z³, Sesso, H D⁴, Stampfer, M J⁵, Stanford, J L⁶

Publikováno v: Prostate Cancer & Prostatic Diseases. Sep2015, Vol. 18 Issue 3, p260-263. 4p.