Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Kjell S Sakariassen"'
Autor:
Masahiro Murakami, Kazunori Otsui, Yoshinobu Ijiri, Muneshige Shimizu, Hideo Ikarugi, Wataru Shioyama, Junichiro Yamamoto, Kjell S Sakariassen
Publikováno v:
Future Science OA, Vol 8, Iss 3 (2022)
Because of the high mortality from myocardial infarction and stroke, there is a great demand for finding novel methods of diagnosis, prevention and treatment of these diseases. Most of the current tests measure important determinants of thrombosis su
Externí odkaz:
https://doaj.org/article/71573bd8f74f4b08a03edc4dc922d3d7
Autor:
Junichiro Yamamoto, Nobutaka Inoue, Kazunori Otsui, Hideo Ikarugi, Muneshige Shimizu, Shinji Yamamoto, Masahiro Murakami, Yoshinobu Ijiri, Kjell S Sakariassen
Publikováno v:
Future Science OA, Vol 5, Iss 6 (2019)
Externí odkaz:
https://doaj.org/article/a7f860664cda4e73a3bc0ab7ba361230
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 17(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba48577b40fc34de23c2430d515d0af
https://pubmed.ncbi.nlm.nih.gov/31479185
https://pubmed.ncbi.nlm.nih.gov/31479185
Autor:
Shinji Yamamoto, Junichiro Yamamoto, Kjell S Sakariassen, Masahiro Murakami, Yoshinobu Ijiri, Nobutaka Inoue, Kazunori Otsui, Hideo Ikarugi, Muneshige Shimizu
Publikováno v:
Future Science OA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7cf20f9448aca8e9625f88f1a579e2
https://pubmed.ncbi.nlm.nih.gov/31285845
https://pubmed.ncbi.nlm.nih.gov/31285845
Autor:
Hideo Ikarugi, Muneshige Shimizu, Yoshinobu Ijiri, Shinji Yamamoto, Junichiro Yamamoto, Kjell S Sakariassen
Publikováno v:
Future Science OA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054ef7f1f94518f7b3838e80c8a5a758
http://europepmc.org/articles/PMC6391630
http://europepmc.org/articles/PMC6391630
Publikováno v:
Future Science OA
The Science for Life Laboratory Drug Discovery and Development Platform (SciLifeLab DDD) was established in Stockholm and Uppsala, Sweden, in 2014. It is one of ten platforms of the Swedish national SciLifeLab which support projects run by Swedish ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc909f9ca2c07f428f76b9618aba728f
http://europepmc.org/articles/PMC5481862
http://europepmc.org/articles/PMC5481862
Autor:
Bhaloo Desai, Ana Muniz-Lozano, Andrew Darlington, Norbert Bender, Ryan E. Wilson, Kjell S. Sakariassen, Ronakkumar Patel, Fabiana Rollini, Francesco Franchi, Dominick J. Angiolillo, Antonio Tello-Montoliu
Publikováno v:
Journal of Thrombosis and Thrombolysis. 37:131-138
Patients with diabetes mellitus (DM) have increased propensity to generate thromboxane A2 (TXA2) and other eicosanoids which can contribute to their heightened platelet reactivity. EV-077 is a potent thromboxane receptor antagonist and thromboxane sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e069ce5e9c1d4a7df11e00c8fc483eff
https://doi.org/10.1007/s11239-013-0979-8
https://doi.org/10.1007/s11239-013-0979-8
Autor:
Kjell S Sakariassen, Pēteris Alberts, Jean-Philippe Meyer, Alexandra Santana Sorensen, A. Richardson
Publikováno v:
European Journal of Clinical Pharmacology. 69:459-465
This study was performed to determine the oral pharmacokinetics (PK) of EV-077 and its effects on pharmacodynamic (PD) markers. EV-077 blocks prostanoid-induced and isoprostane-induced cellular activation, and is in development for the treatment of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a0599e2934f9c7cac16fc2ee89b4a4
https://doi.org/10.1007/s00228-012-1348-9
https://doi.org/10.1007/s00228-012-1348-9
Autor:
Bill Davis, Gavin E. Jarvis, Nicholas Pugh, Kjell S. Sakariassen, Richard W. Farndale, Annelize Koch
Publikováno v:
Journal of Thrombosis and Thrombolysis. 33:6-15
This study was designed to assess the effect of Factor Xa antagonists on thrombus formation at various axial positions on a tissue factor rich surface under arterial blood flow conditions. Non-anticoagulated, flowing human blood, drawn directly from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b16c65337998e3863b54a010203c0a
https://doi.org/10.1007/s11239-011-0658-6
https://doi.org/10.1007/s11239-011-0658-6
Autor:
Junichiro Yamamoto, Hideo Ikarugi, Yoshinobu Ijiri, Kazunori Otsui, Nobutaka Inoue, Kjell S Sakariassen
Publikováno v:
Future Science OA
Prevention of thrombotic disorders has priority over treatment. There are only two pathologically relevant tests which are suitable for measuring the overall thrombotic status both in experimental conditions and in humans. The Global Thrombosis Test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9729e076935a4f7c64d5ef6f89eecb
https://doi.org/10.4155/fsoa-2017-0104
https://doi.org/10.4155/fsoa-2017-0104