Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Kjell M. Vårum"'
Autor:
Vincent G. H. Eijsink, Kjell M. Vårum, Morten Sørlie, Anne Line Norberg, Ellinor B. Heggset, Berit B. Aam
Publikováno v:
Marine Drugs, Vol 8, Iss 5, Pp 1482-1517 (2010)
Chitooligosaccharides (CHOS) are homo- or heterooligomers of N-acetylglucosamine and D-glucosamine. CHOS can be produced using chitin or chitosan as a starting material, using enzymatic conversions, chemical methods or combinations thereof. Productio
Externí odkaz:
https://doaj.org/article/796b79d3540d479baab9e30ea4d07041
Publikováno v:
Food Hydrocolloids. 48:174-178
Chitosan is a biopolymer that can be used in food applications such as forming edible coatings and nanoparticles. It is a linear polysaccharide composed of neutral (acetylated) and positively (deacetylated) sugar units and can be prepared with varyin
Autor:
Thang Trung Khong, Kurt Ingar Draget, Gudmund Skjåk-Bræk, Olav Andreas Aarstad, Kjell M. Vårum
Publikováno v:
Biomacromolecules. 14:2765-2771
Biocompatible hydrogels are very interesting for applications in, e.g., tissue engineering and for immobilization of cells, such as calcium-alginate gels where the calcium ions form specific interactions with the guluronic acid units. We here report
Publikováno v:
Carbohydrate Polymers. 94:436-443
Chitosan is widely explored as a gene delivery vehicle due to its ability to condense DNA, facilitate transport, and subsequent release allowing gene expression, as well as protecting the DNA. Here, we investigate the enhancement of chitosan-DNA disp
Publikováno v:
Journal of Controlled Release. 158:261-268
Chitosan has gained increasing interest for siRNA delivery. Although chitosan covers a family of structurally different polysaccharides, most siRNA delivery studies have been performed with conventional partially N -acetylated chitosans. Herein, the
Publikováno v:
Biomacromolecules. 12:721-729
Chitosan possesses many characteristics of an ideal gene delivery system. However, the transfection efficiency of conventional chitosans is generally found to be low. In this study, we investigated the self-branching of chitosans as a strategy to imp
Publikováno v:
Carbohydrate Polymers. 83:1558-1564
Fully de-N-acetylated chito-oligomers were prepared by de-amination of chitosan using nitrous acid (HNO2). The dimer to hexamer fractions of chitosan oligomers were fractionated with preparative size-exclusion chromatography (SEC) and characterized u
Autor:
Mamiko Mizuhara, Takuo Osawa, Tomoyuki Numata, Takayuki Ohnuma, Kjell M. Vårum, Tamo Fukamizo
Publikováno v:
Plant Molecular Biology. 75:291-304
A class V chitinase from Nicotiana tabacum (NtChiV) with amino acid sequence similar to that of Serratia marcescens chitinase B (SmChiB) was expressed in E. coli and purified to homogeneity. When N-acetylglucosamine oligosaccharides [(NAG)(n)] were h
Autor:
Henrik Zakariassen, Shohei Sakuda, Morten Sørlie, Gustav Vaaje-Kolstad, Laila Klemetsen, Vincent G. H. Eijsink, Kjell M. Vårum
Publikováno v:
Carbohydrate Polymers. 82:779-785
Many glycoside hydrolases, such as chitinases and cellulases, degrade polysaccharides in a processive manner. Inhibition of chitinases is of great interest, because chitin-metabolizing pathogenic organisms such as certain fungi, insects and nematodes
Autor:
Ellinor Bævre Heggset, Anette I. Dybvik, Vincent G. H. Eijsink, Anne Line Norberg, Ingunn A. Hoell, Kjell M. Vårum, Morten Sørlie
Publikováno v:
Biomacromolecules. 11:2487-2497
We have studied the degradation of well-characterized soluble heteropolymeric chitosans by a novel family 46 chitosanase, ScCsn46A from Streptomyces coelicolor A3(2), to obtain insight into the enzyme's mode of action and to determine its potential f