Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kjell A. Mortier"'
Autor:
Willy E Lambert, Annie Van Gussem, Vincent Renard, Simon Van Belle, Alain Verstraete, Kjell A. Mortier
Publikováno v:
Analytical Chemistry. 77:4677-4683
A quantitative method for the simultaneous determination of docetaxel (Taxotere), paclitaxel (Taxol), 6alpha-hydroxypaclitaxel, and p-3'-hydroxypaclitaxel in human plasma and oral fluid is developed and validated. Oral fluid (this term is now preferr
Publikováno v:
Journal of the American Society for Mass Spectrometry. 15:585-592
Quantitative analysis of target compounds with liquid chromatography atmospheric pressure ionization mass spectrometry is sometimes hampered by adduct formation. In these situations, cationization with alkali metal ions instead of proton addition is
Autor:
R Dams, Marc Espeel, Karine M. Clauwaert, Els A. De Letter, Willy E. Lambert, Michel Piette, Kjell A. Mortier, Marijke Craeymeersch
Publikováno v:
International Journal of Legal Medicine. 117:2-9
Abuse of amphetamine derivatives such as 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) is an important issue in current forensic practice and fatalities are not infrequent. Therefore, we investigated an immunohistoc
Autor:
Dieter Deforce, Carlos Van Peteghem, Karine M. Clauwaert, Willy E. Lambert, Kristof E. Maudens, Kjell A. Mortier, Jan Van Bocxlaer, André P. De Leenheer
Publikováno v:
Journal of Chromatography B. 779:321-330
A method using liquid chromatography coupled to tandem mass spectrometry is described for the determination of drugs of abuse in oral fluid. The method is able to simultaneously quantify amphetamines (amphetamine, methamphetamine, MDA, MDMA and MDEA)
Autor:
Kjell A. Mortier, Els A. De Letter, R Dams, Serge Van Calenbergh, André P. De Leenheer, Willy E. Lambert
Publikováno v:
Rapid Communications in Mass Spectrometry. 16:865-870
Paramethoxyamphetamine (PMA) is an amphetamine-like designer drug that has emerged recently on the European illicit drug market. This drug has a wicked reputation, as a number of lethal intoxications have occurred. A method using high-performance liq
Autor:
Elfriede G. Van den Eeckhout, Carlos Van Peteghem, André P. De Leenheer, Jan Van Bocxlaer, Karine M. Clauwaert, Willy E. Lambert, Kjell A. Mortier
Publikováno v:
Rapid Communications in Mass Spectrometry. 15:1773-1775
Publikováno v:
Journal of chromatography. A. 1123(1)
When developing an LC-MS/MS-method matrix effects are a major issue. The effect of co-eluting compounds arising from the matrix can result in signal enhancement or suppression. During method development much attention should be paid to diminish matri
Autor:
Kjell A. Mortier, Willy E. Lambert
Publikováno v:
Journal of chromatography. A. 1108(2)
This work describes the development of a straightforward method for the determination of free docetaxel and paclitaxel in plasma. The separation of bound and unbound drug was performed with ultrafiltration. Different ultrafiltration devices were eval
Publikováno v:
Journal of chromatography. A. 1041(1-2)
Liquid chromatography–tandem mass spectrometry (LC–MS–MS) is often performed in a high-throughput environment. Unfortunately, with atmospheric pressure ionization (API) techniques, shorter run-times or reduced sample clean-up often result in io
Autor:
E. A. De Letter, A.P. De Leenheer, Michel Piette, Willy E. Lambert, S. Van Calenbergh, R Dams, Jan Cordonnier, Kjell A. Mortier
Publikováno v:
Journal of analytical toxicology. 27(5)
We present a fatal case involving the combined ingestion of amphetamine, 3,4-methylenedioxymethylamphetamine, 3,4-methylenedioxyamphetamine, and paramethoxyamphetamine. Various postmortem specimens (e.g., several blood samples, urine, and tissue samp