Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kizhake V. Soman"'
Autor:
Vladimir Jovasevic, Hui Zhang, Farahnaz Sananbenesi, Anita L. Guedea, Kizhake V. Soman, John E. Wiktorowicz, Andre Fischer, Jelena Radulovic
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102617- (2021)
Summary: It is well established that the formation of episodic memories requires multiple hippocampal mechanisms operating on different time scales. Early mechanisms of memory formation (synaptic consolidation) have been extensively characterized. Ho
Externí odkaz:
https://doaj.org/article/7dc58fa784c7426a83e6b996acc4e7f1
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 4, Pp 623-635 (1999)
APOBEC1 is the catalytic subunit of an enzyme complex that mediates apolipoprotein (apo) B mRNA editing. It dimerizes in vitro and requires complementation factor(s) for its editing activity. We have performed a systematic analysis of the structure
Externí odkaz:
https://doaj.org/article/8b954dcd6c944eae99e110d96435d559
Autor:
Nisha Jain Garg, Kizhake V Soman, Maria P Zago, Sue-Jie Koo, Heidi Spratt, Susan Stafford, Zinzi N Blell, Shivali Gupta, Julio Nuñez Burgos, Natalia Barrientos, Allan R Brasier, John E Wiktorowicz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004490 (2016)
Trypanosoma cruzi (Tc) infection causes chagasic cardiomyopathy; however, why 30-40% of the patients develop clinical disease is not known. To discover the pathomechanisms in disease progression, we obtained the proteome signature of peripheral blood
Externí odkaz:
https://doaj.org/article/2c150de3294b493f9cceec800b7074a9
Autor:
John E. Wiktorowicz, Farahnaz Sananbenesi, Jelena Radulovic, Hui Zhang, Andre Fischer, Vladimir Jovasevic, Kizhake V. Soman, Anita L. Guedea
Publikováno v:
iScience 24(6), 102617-(2021). doi:10.1016/j.isci.2021.102617
iScience
iScience, Vol 24, Iss 6, Pp 102617-(2021)
iScience
iScience, Vol 24, Iss 6, Pp 102617-(2021)
Summary It is well established that the formation of episodic memories requires multiple hippocampal mechanisms operating on different time scales. Early mechanisms of memory formation (synaptic consolidation) have been extensively characterized. How
Autor:
Kamlesh K. Bhopale, Samir M. Amer, Lata Kaphalia, Ghulam Ansari, Bhupendra S. Kaphalia, John E. Wiktorowicz, Kizhake V. Soman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:1675-1685
Background Chronic alcohol abuse, a major risk factor for such diseases as hepatitis and cirrhosis, impairs hepatic alcohol dehydrogenase (ADH; key ethanol [EtOH]-metabolizing enzyme). Therefore, differentially altered hepatic and plasma proteomes we
Autor:
Samir M. Amer, Lata Kaphalia, Kamlesh K. Bhopale, Kizhake V. Soman, Ghulam Ansari, John E. Wiktorowicz, Bhupendra S. Kaphalia
Publikováno v:
Pancreas. 46:806-812
ObjectivesThe aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase–deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatiti
Autor:
Melinda Sheffield-Moore, William J. Durham, Kathleen M. Randolph, Ria Sur, E. Lichar Dillon, Randall J. Urban, Christopher P. Danesi, Daniel C. Jupiter, Charles R. Gilkison, Kizhake V. Soman, John E. Wiktorowicz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0217690 (2019)
PLoS ONE, Vol 14, Iss 6, p e0217690 (2019)
IntroductionLong-term head-down bed rest (HDBR) results in musculoskeletal losses similar to those observed during long-term space flight. Agents such as testosterone, in addition to regular exercise, are effective countermeasures for reducing loss o
Autor:
Konrad Pazdrak, Wendy I. White, Xuemei Luo, Susan Stafford, Alexander Kurosky, Zheng Wu, Kizhake V. Soman, John E. Wiktorowicz, William J. Calhoun
Publikováno v:
Journal of proteome research. 16(8)
Activated eosinophils contribute to airway dysfunction and tissue remodeling in asthma and thus are considered to be important factors in asthma pathology. We report here comparative proteomic and phosphoproteomic changes upon activation of eosinophi
Autor:
John E, Wiktorowicz, Kizhake V, Soman
Publikováno v:
Advances in experimental medicine and biology. 919
Properly performed, biomarker discovery can lead to effective candidates that can ultimately serve as predictors of disease, medical condition, define therapeutic parameters, and many other applications in medicine. Preferably, biomarkers comprise a
Autor:
Kizhake V. Soman, Shannon L. Casperson, Edgar L. Dillon, Lori L. Ploutz-Snyder, P B S James Lynch, Susan D. McCammon, Gregory R. White, John E. Wiktorowicz, Astrid M. Horstman, Kristofer Jennings, Joni A. Mettler, M B S Kathleen Randolph, Jean W. Hsu, Dennis C. Gore, Melinda Sheffield-Moore, Barbara M. Doucet, William J. Durham, Christopher P. Danesi, Farook Jahoor, Michael P. Kinsky, Jeffrey W. Ryder
Publikováno v:
Clinical and Translational Science. 6:463-468
Reductions in skeletal muscle function occur during the course of healthy aging as well as with bed rest or diverse diseases such as cancer, muscular dystrophy, and heart failure. However, there are no accepted pharmacologic therapies to improve impa