Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kiyoto Kurima"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract During hair cell development, the mechanoelectrical transduction (MET) apparatus is assembled at the stereocilia tips, where it coexists with the stereocilia actin regulatory machinery. While the myosin-based tipward transport of actin regul
Externí odkaz:
https://doaj.org/article/45ce34e9424e4923bd57114f2fb7782b
Autor:
Karina Uehara, Yasuka Tanabe, Shintaro Hirota, Saki Higa, Zensei Toyoda, Kiyoto Kurima, Shinichiro Kina, Toshiyuki Nakasone, Akira Arasaki, Takao Kinjo
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Low-risk human papillomavirus (HPV), such as types 6 and 11, is considered non-oncogenic, but these types have been detected in oral cancer tissue samples, suggesting their possible involvement in oral carcinogenesis. Because doub
Externí odkaz:
https://doaj.org/article/402d239eebdb4a3badbf39e788fc3f5d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Adeno-associated viral (AAV) vectors, used as vehicles for gene transfer into the brain, are a versatile and powerful tool of modern neuroscience that allow identifying specific neuronal populations, monitoring and modulating their activity. For cons
Externí odkaz:
https://doaj.org/article/929b174d658a488aba05af84669ab049
Autor:
Kiyoto Kurima, Seham Ebrahim, Bifeng Pan, Miloslav Sedlacek, Prabuddha Sengupta, Bryan A. Millis, Runjia Cui, Hiroshi Nakanishi, Taro Fujikawa, Yoshiyuki Kawashima, Byung Yoon Choi, Kelly Monahan, Jeffrey R. Holt, Andrew J. Griffith, Bechara Kachar
Publikováno v:
Cell Reports, Vol 12, Iss 10, Pp 1606-1617 (2015)
Mechanosensitive ion channels at stereocilia tips mediate mechanoelectrical transduction (MET) in inner ear sensory hair cells. Transmembrane channel-like 1 and 2 (TMC1 and TMC2) are essential for MET and are hypothesized to be components of the MET
Externí odkaz:
https://doaj.org/article/956b6b945a184c899793d843c0c644ab
Autor:
Taku Ito, Xiangming Li, Kiyoto Kurima, Byung Yoon Choi, Philine Wangemann, Andrew J. Griffith
Publikováno v:
Neurobiology of Disease, Vol 66, Iss , Pp 53-65 (2014)
SLC26A4 mutations can cause a distinctive hearing loss phenotype with sudden drops and fluctuation in patients. Existing Slc26a4 mutant mouse lines have a profound loss of hearing and vestibular function, with severe inner ear malformations that do n
Externí odkaz:
https://doaj.org/article/b20cdf786ace4ee1a4a2cd4a39110611
Autor:
Kiyoto Kurima, Ronna Hertzano, Oksana Gavrilova, Kelly Monahan, Karl B Shpargel, Garani Nadaraja, Yoshiyuki Kawashima, Kyu Yup Lee, Taku Ito, Yujiro Higashi, David J Eisenman, Scott E Strome, Andrew J Griffith
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002307 (2011)
Heterozygous Twirler (Tw) mice develop obesity and circling behavior associated with malformations of the inner ear, whereas homozygous Tw mice have cleft palate and die shortly after birth. Zeb1 is a zinc finger protein that contributes to mesenchym
Externí odkaz:
https://doaj.org/article/d1741a64f74143599b23fb6a0d371f49
Autor:
Ronna Hertzano, Ran Elkon, Kiyoto Kurima, Annie Morrisson, Siaw-Lin Chan, Michelle Sallin, Andrew Biedlingmaier, Douglas S Darling, Andrew J Griffith, David J Eisenman, Scott E Strome
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002309 (2011)
Cellular heterogeneity hinders the extraction of functionally significant results and inference of regulatory networks from wide-scale expression profiles of complex mammalian organs. The mammalian inner ear consists of the auditory and vestibular sy
Externí odkaz:
https://doaj.org/article/be78cbca14b74fb4b2eb96c2e8f7ef78
Autor:
Akiyuki Sugisawa, Zensei Toyoda, Yasuka Tanabe, Karina Uehara, Aya Oshiro, Reo Yamazato, Chiharu Sakamoto, Shohei Yogi, Kiyoto Kurima, Shinichiro Kina, Michiyo Sakiyama, Takao Kinjo
Publikováno v:
Menopause. 30:193-200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf139eaa2768401e6659cbda7bd8896
https://doi.org/10.1097/gme.0000000000002125
https://doi.org/10.1097/gme.0000000000002125
Autor:
Lawrence E. Samelson, Grace Bugos, Lijin Dong, Sunmee Huh, Connie L. Sommers, Xing Li, Chuan-Jin Wu, Wenmei Li, Kiyoto Kurima, Andrew J. Griffith
Publikováno v:
J Biol Chem
The TMC genes encode a set of homologous transmembrane proteins whose functions are not well understood. Biallelic mutations in either TMC6 or TMC8 are detected in more than half of cases of the pre-malignant skin disease epidermodysplasia verrucifor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225db6a6ff3c37fd722103681a3887d3
https://doi.org/10.1074/jbc.ra120.013045
https://doi.org/10.1074/jbc.ra120.013045
Autor:
Yoshiyuki Kawashima, Taku Ito, Taro Fujikawa, Kiyoto Kurima, Andrew J. Griffith, Yuriko Sakamaki, Ayane Makabe, Takeshi Tsutsumi, Ayako Maruyama
Publikováno v:
J Assoc Res Otolaryngol
Systemically administered aminoglycoside antibiotics can enter inner ear hair cells and trigger apoptosis. However, the in vivo route(s) by which aminoglycoside antibiotics enter hair cells remains controversial. Aminoglycosides can enter mouse hair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822f4424a9d380ad4c3b5033a4e79070
https://doi.org/10.1007/s10162-020-00746-3
https://doi.org/10.1007/s10162-020-00746-3