Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kiyoto Kanbara"'
Autor:
Kiyoto Kanbara, Yoshinori Otsuki, Masahito Watanabe, Syunichi Yokoe, Yoshiaki Mori, Michio Asahi, Masashi Neo
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background High-grade chondrosarcoma, which has a high incidence of local recurrence and pulmonary metastasis despite surgical resection, is associated with poor prognosis. Therefore, new and effective adjuvant therapies are urgently require
Externí odkaz:
https://doaj.org/article/e5cb0a217815405e8ce176a8d30fff82
Publikováno v:
Acta histochemica. 120(2)
Chondrosarcoma is a malignant bone tumor that produces cartilaginous neoplastic tissue. Owing to the absence of an effective adjuvant therapy, high-grade chondrosarcoma has a poor prognosis. Therefore, it is important to develop an effective adjuvant
Autor:
Mitsuo Kinoshita, Shinji Hirofuji, Atsushi Yokota, Katsunori Ohno, Hisashi Ohtsuka, Kiyoto Kanbara
Publikováno v:
Journal of Orthopaedic Research. 28:481-486
To elucidate the pathophysiological mechanisms underlying chronic nerve-stretch injury, we gradually lengthened rat femurs by 15 mm at the rate of 0.5 mm/day (group L, n = 13). The control groups comprised sham-operated (group S, n = 10) and naive (g
Autor:
Kunihiko Obata, Masami Yabumoto, Haruhito Azuma, Kentaro Maemura, Yuchio Yanagawa, Masahito Watanabe, Yoji Katsuoka, Hana Hayasaki, Hirokazu Abe, Kiyoto Kanbara
Publikováno v:
Journal of Andrology. 26:568-577
gamma-Aminobutyric acid (GABA), which is a major inhibitory neurotransmitter in the brain, is also found in many peripheral nonneuronal tissues, including male reproductive organs. However, the distribution of GABAergic cells in various organs is not
Autor:
Kiyoto Kanbara, Keiko Okamoto, Ryuichi Shigemoto, Sakashi Nomura, Masahito Watanabe, Haruhito Azuma, Takeshi Kaneko, Yoji Katsuoka
Publikováno v:
Journal of Andrology. 26:485-493
The GABAergic system, a major inhibitory regulator in the central nervous system, may also play important roles in peripheral nonneuronal tissues and cells. Recent studies showed that GABA B receptor is expressed in testis and sperm. To understand th
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 34:201-206
The distribution of γ-aminobutyrate (GABA) and its synthesizing enzyme glutamate decarboxylase (GAD) in the epiphyseal growth plate of the rat long bone was studied by immunohistochemistry. GABA, GAD65 and GAD67 immunoreactive chondrocytes were foun
Publikováno v:
Acta Histochemica. 103:355-363
In the present study, differences in glucose uptake by muscle fibers in deep, middle, and superficial regions of the gastrocnemius were studied at rest by 2-deoxyglucose (2-DG) microautoradiography. Expression of the glucose transporter 4 (GLUT-4) pr
Autor:
Kiyoto Kanbara, Masahito Watanabe, Muneaki Abe, Hana Hayasaki, Hidetsugu Ohara, Takumi Tamayama, Kentaro Maemura
Publikováno v:
Acta Histochemica. 103:365-378
Summary The epiphyseal growth plate, where chondrocytes proliferate and differentiate, is the major site for longitudinal bone growth, matrix synthesis and mineralization. Glucose is an important energy source for the metabolism and growth of chondro
Autor:
Masahiro Takafuchi, Hana Hayasaki, Masahisa Shimada, Yutaka Watanabe, Masahito Watanabe, Kiyoto Kanbara, Nobuo Jo
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 29:207-213
A fluorescent glucose analogue, 6-deoxy-N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-aminoglucose (NBDG) has been used for studies of glucose transport. The fluorescence from NBDG was observed with a confocal laser scanning microscope (CLSM). The fluoresce
Publikováno v:
Neuroscience. 218
It is well known that Gamma-aminobutyric acid (GABA) plays an important role in signal transduction in the central nervous system. However, the function of GABA in the peripheral nervous system, including sensory ganglions, is still unclear. In this