Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Kiyoto Hara"'
1
The effect of ceria content in nickel–ceria composite anode catalysts on the discharge performance for solid oxide fuel cells
Autor: Yoshihiko Ninomiya, Kiyoto Hara, Kenji Okudaira, Yuta Inoue, Tomoaki Namioka, Hibiki Ito
Publikováno v: International Journal of Hydrogen Energy. 43:2394-2401
Optimum ceria content in nickel–ceria composite anode catalyst from the point of discharge performance is discussed. The ohmic loss increased when the ceria content was higher than 30 mol%. Even though the electrical conductivity of the anode decre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd1468db4ca14e27ce19ff0d92c5bb66
https://doi.org/10.1016/j.ijhydene.2017.12.031
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2
Evaluation of a New Blood Coagulation Factor Xa Inhibitor, KFA-1411, as an Anticoagulant in a Cynomolgus Monkey Hemodialysis Model: Parameters Suitable for Monitoring Anticoagulant Activities
Autor: Kiyoto Hara, Masami Kojima, Satoshi Akahane, Takashi Koizumi, Toshiki Honma, Yuji Hoyano, Masahiko Uchida, Masuo Akahane
Publikováno v: Journal of Health Science. 49:368-378
A Cynomolgus monkey hemodialysis model was used to evaluate the efficacy of a new factor Xa (FXa) inhibitor as an anticoagulant for hemodialysis. We tested the selective FXa inhibitor KFA-1411, using doses of 0.15 mg/ kg/hr, 0.3 mg/kg/hr, and 0.6 mg/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b3f8207a364ce89a0818547b150f893
https://doi.org/10.1248/jhs.49.368
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3
Characteristics of the hemostatic action of KFA-1411, an inhibitor of coagulation factor Xa (FXa), in humans and various animals
Autor: Masami Kojima, Takashi Koizumi, Kiyoto Hara, Atsushi Matsuzawa, Akane Matsuzawa, Masahiko Uchida, Satoshi Akahane, Toshiki Honma
Publikováno v: The Journal of Toxicological Sciences. 28:25-34
This study examined a low-molecular-weight factor-Xa inhibitor, KFA-1411 (3-[N-(3-amidinophenyl)-N-[N-[4-[1-(1-iminoethyl)piperidin-4- yl]phenyl]carbamoylmethyl]aminomethyl]phenoxyacetic acid monosulfonate-dihydrate). KFA-1411 selectively inhibited F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc4637af4c2232582bf2efa6f8e20c2
https://doi.org/10.2131/jts.28.25
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5
Prophylactic Effects Of Pilocarpine Hydrochloride On Xerostomia Models Induced By X-Ray Irradiation In Rats
Autor: Keiko Misawa, Yoshimitsu Komatsu, Tetsuya Asari, Kiyoto Hara, Masuo Akahane
Publikováno v: Clinical and Experimental Pharmacology and Physiology. 28:545-550
1. In the present study, we investigated the prophylactic effects of pilocarpine hydrochloride on xerostomia models induced by either single (15 Gy) or repeated (8.6 Gy x3 days) X-ray irradiation in rats. Pilocarpine hydrochloride was administered or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e5c06115b5b4c4e092ec60ad936205
https://doi.org/10.1046/j.1440-1681.2001.03485.x
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6
A method for aerosol particle removal by applying condensation phenomena
Autor: Tetsu Fujii, Kiyoto Hara, Shigeru Koyama, Ken Kuwahara
Publikováno v: Heat Transfer - Japanese Research. 26:398-409
This paper describes an experimental study on a method of removing aerosol particles from air by condensing heated and humidified air. In the experiment, air, including aerosol particles, is circulated by a fan in a closed clean room system consistin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d6c05a7db6b8006dc371401d2e3b244
https://doi.org/10.1002/(sici)1520-6556(1997)26:6<398::aid-htj5>3.0.co
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7
Orally active factor Xa inhibitors: investigation of a novel series of 3-amidinophenylsulfonamide derivatives using an amidoxime prodrug strategy
Autor: Harunobu Mukaiyama, Hideyuki Muranaka, Hiroaki Kobayashi, Masahiko Uchida, Tomonaga Ozawa, Yasuoki Murakami, Kosuke Okazaki, Yuji Hoyano, Yuichiro Kai, Hiroaki Okuno, Norihiko Kikuchi, Kenji Yokoyama, Hiroaki Shiohara, Kiyoto Hara, Eiichi Tsuji, Takashi Koizumi, Hidetoshi Isawa, Hideki Takeuchi, Keiko Misawa, Shigeru Nakano
Publikováno v: Bioorganicmedicinal chemistry letters. 18(16)
A series of novel and potent 3-amidinophenylsulfonamide derivatives of factor Xa inhibitors were designed and synthesized using an amidoxime prodrug strategy. We focused on systemic clearance of parent compounds in rats, and performed in vivo pharmac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886bf33ad748cc1add1bf5be3dafc9b0
https://pubmed.ncbi.nlm.nih.gov/18667303
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8
Suppressive Effects of the Anti-al1ergic Drugs, Tranilast and Azelastine, on the Lysophosphatidylserine-Dependent Activation of Rat Mast Cells
Autor: Ichiro Kudo, Keizo Inoue, Hidetada Komatsu, Kiyoto Hara, Arao Ujiie, Naoyuki Tsutsumi, Tetsuyuki Kobayashi, Shigeru Ikeda
Publikováno v: Biological and Pharmaceutical Bulletin. 17:1121-1123
Anti-allergic drugs, tranilast and azelastine, were examined for their effects on lysophosphatidylserine (lysoPS)-dependent histamine release from rat mast cells. Although both compounds suppressed the histamine release in a dose-dependent manner, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3e0cec86ffd0470c1be971ba18e15b1
https://doi.org/10.1248/bpb.17.1121
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