Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kiyotaka Iwai"'
Autor:
Kiyotaka Iwai, Norio Fujiwara, Ayumu Kurimoto, Shinobu Murata, Hajime Kawakami, Hitoshi Fujita
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1317-1320
New piperidylpyrimidine derivatives, including quinazolines, were prepared, and their abilities to inhibit TNF-alpha production evaluated. Some compounds showed potent inhibitory activity in mouse macrophages stimulated with LPS. The synthesis and st
Autor:
Atsushi Tsuchida, Kiyotaka Iwai, Katsunori Maruta, Jun Nagamine, Kantaro Ushiroda, Ryu Nagata, Mutsuo Taiji, Makoto Kitoh
Publikováno v:
ChemInform. 42
A series of benzoylpyrrole-based carboxylic acids are designed and synthesized as peroxisome proliferator-activated receptor (PPAR) activators.
Autor:
Mutsuo Taiji, Ryu Nagata, Jun Nagamine, Makoto Kitoh, Katsunori Maruta, Kantaro Ushiroda, Kiyotaka Iwai, Atsushi Tsuchida
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(1)
Starting with a subtle blood glucose-lowering effect of a TGF-β inhibitor, we designed and synthesized a series of benzoylpyrrole-based carboxylic acids as PPARs activators. Among these compounds, 10sNa exhibited favorable blood glucose-lowering eff
Autor:
Hitoshi Fujita, Ayumu Kurimoto, Hajime Kawakami, Kiyotaka Iwai, Shinobu Murata, Norio Fujiwara
Publikováno v:
ChemInform. 31
New piperidylpyrimidine derivatives, including quinazolines, were prepared, and their abilities to inhibit TNF-alpha production evaluated. Some compounds showed potent inhibitory activity in mouse macrophages stimulated with LPS. The synthesis and st
Publikováno v:
Tetrahedron Letters. 31:5041-5042
A γ-azetidinyl-β-hydroxy-α-amino acid moiety of mugineic acid ( 1 ) was stereoselectively prepared as its protected form 2 from (R)-glyceric acid derivative 3 , providing an alternative synthesis of mugineic acid (1).