Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kiyotaka Akiyama"'
Autor:
Idam Hermawan, Mikako Higa, Philipus Uli Basa Hutabarat, Takeshi Fujiwara, Kiyotaka Akiyama, Akihiko Kanamoto, Takahiro Haruyama, Nobuyuki Kobayashi, Masahiro Higashi, Shoichiro Suda, Junichi Tanaka
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 353 (2019)
On our quest for new bioactive molecules from marine sources, two cyclic imines (1, 2) were isolated from a dinoflagellate extract, inhibiting the growth of the respiratory syncytial virus (RSV). Compound 1 was identified as a known molecule portimin
Externí odkaz:
https://doaj.org/article/cc59c0cce2fc4d93bfb73e9588ec63a2
Publikováno v:
Neuroscience. 187:15-23
Our previous study suggests that "the neuropeptidergic system" might promote a diversity of the mechanisms that regulate signal transmission in the hippocampus. Cholecystokinin (CCK) is the mostly expressed neuropeptide gene in the hippocampus. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948ee30219d955dff6d42ad7f003271f
https://doi.org/10.1016/j.neuroscience.2011.04.031
https://doi.org/10.1016/j.neuroscience.2011.04.031
Publikováno v:
Hippocampus. 21:1228-1239
We have shown quantitative expression levels of genes coding for the "ligand-receptor system" for classical neurotransmitters and neuropeptides in hippocampal subregions CA1, CA3, and dentate gyrus (DG). Using a combination of DNA microarray and quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f1de02b06df923a0695fa65f39ee20
https://doi.org/10.1002/hipo.20830
https://doi.org/10.1002/hipo.20830
Autor:
Mutsushi Matsuyama, Kiyoko Nakano, Kiyotaka Akiyama, Shiro Suetsugu, Noriko Wakisaka, Hiroyuki Morita, Seiko Kuraba, Yasuharu Numata, Kiyoko Inui, Hiroaki Oniki, Ashio Yoshimura, Terukuni Ideura, Yoshihisa Yamamoto, Tadaomi Takenawa
Publikováno v:
Mammalian Genome. 19:41-50
The BUF/Mna strain of rat is a model of focal and segmental glomerulosclerosis (FSGS) in which a quantitative trait locus (QTL) for proteinuria, Pur1, has been identified. The aim of the present study was to identify candidates for the Pur1 gene. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0691402688b259fc9cc05032f2af5968
https://doi.org/10.1007/s00335-007-9078-5
https://doi.org/10.1007/s00335-007-9078-5
Autor:
Kiyotaka Akiyama, Masato Noguchi, Hitoshi Sasai, Atsuko Kushi, Takayuki Yoshida, Koji Edamura
Publikováno v:
Experimental Animals. 53:437-443
Alpha-1-antitrypsin (alpha1-AT) is a member of the serine protease inhibitor family regulating numerous proteolytic processes. The genetic disorder, alpha1-AT deficiency, is well known as a cause of hereditary pulmonary emphysema and liver cirrhosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb2c2ff7f482cde8d3847371ec01f33
https://doi.org/10.1538/expanim.53.437
https://doi.org/10.1538/expanim.53.437
Publikováno v:
FEBS Letters. 455:59-62
Arsenic trioxide (As2O3) induces clinical remission in acute promyelocytic leukemia, even in all-trans retinoic acid-refractory cases, with minimal toxicity at low (1–2 μM) concentration. We exposed various neuroblastoma cell lines to As2O3 at a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c400ea12168eb6c663e73d7465b8557
https://doi.org/10.1016/s0014-5793(99)00841-8
https://doi.org/10.1016/s0014-5793(99)00841-8
Publikováno v:
Mammalian Genome. 9:269-273
A method of generating mice from embryonic stem (ES) cells with a large chromosomal deletion produced by X-ray irradiation has been developed. Fifty-two mutant ES clones were made that carried a nested set of chromosomal deletions up to approximately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f814bc03194938901fd013e86284cd5
https://doi.org/10.1007/s003359900747
https://doi.org/10.1007/s003359900747
Autor:
Yoshisuke Nishi, Masahiro Yokoyama, Tadashi Matsunaga, Naotoshi Kanda, Tohru Noguchi, Kiyotaka Akiyama
Publikováno v:
Genes, Chromosomes and Cancer. 15:129-133
A DEAD box gene (DDX1) characterized by a motif with a putative RNA helicase was found at elevated levels, with multiple copies, in a neuroblastoma and in some retinoblastoma cell lines in which the MYCN gene was amplified. The present study was aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e735d50829263b87909b2cac63706ba0
https://doi.org/10.1002/(sici)1098-2264(199602)15:2<129::aid-gcc8>3.0.co
https://doi.org/10.1002/(sici)1098-2264(199602)15:2<129::aid-gcc8>3.0.co
Publikováno v:
ChemInform. 43
isolation and structure elucidation of the yellow pigment, halichrome A (I) which shows cytotoxicity against B16 melanoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cc43ca0f4ee96aa0dfdb00d6d756af
https://doi.org/10.1002/chin.201248193
https://doi.org/10.1002/chin.201248193
Autor:
Fatma Pinar Sahin, Mizoe Kishigami, Kenji Miyamoto, Kiyotaka Akiyama, Takayuki Naito, Takahiro Abe, Yasufumi Sakakibara, Daisuke Uemura
Publikováno v:
Bioscience, biotechnology, and biochemistry. 76(4)
Symbionts of the marine sponge Halichondria okadai are promising as a source of natural products. Metagenomic technology is a powerful tool for accessing the genetic and biochemical potential of bacteria. Hence, we established a method of recovering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dae4c443d87cd7c7063922925b14c78
https://pubmed.ncbi.nlm.nih.gov/22484923
https://pubmed.ncbi.nlm.nih.gov/22484923