Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Kiyotaka, Hitomi"'
Autor:
Yoshiki Shinoda, Hideki Tatsukawa, Atsushi Yonaga, Ryosuke Wakita, Taishu Takeuchi, Tokuji Tsuji, Miyako Tanaka, Takayoshi Suganami, Kiyotaka Hitomi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-14 (2023)
Abstract Macrophages are important components in modulating homeostatic and inflammatory responses and are generally categorized into two broad but distinct subsets: classical activated (M1) and alternatively activated (M2) depending on the microenvi
Externí odkaz:
https://doaj.org/article/60a8363128b6446cb25e9a900b1c1a02
Autor:
Jasmina Damnjanović, Nana Odake, Jicheng Fan, Maurizio Camagna, Beixi Jia, Takaaki Kojima, Naoto Nemoto, Kiyotaka Hitomi, Hideo Nakano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract cDNA display is an in vitro display technology based on a covalent linkage between a protein and its corresponding mRNA/cDNA, widely used for the selection of proteins and peptides from large libraries (1012) in a high throughput manner, bas
Externí odkaz:
https://doaj.org/article/2aa62fee1b9347f89eab4fb2cdc84768
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract Chronic kidney disease is characterized by prolonged decline in renal function, excessive accumulation of ECM, and progressive tissue fibrosis. Transglutaminase (TG) is a crosslinking enzyme that catalyzes the formation of covalent bonds bet
Externí odkaz:
https://doaj.org/article/66086460911a4f87a48181ed1f80a081
Autor:
Hideki Tatsukawa, Kiyotaka Hitomi
Publikováno v:
Cells, Vol 10, Iss 7, p 1842 (2021)
Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme catalyzing the crosslinking between Gln and Lys residues and involved in various pathophysiological events. Besides this crosslinking activity, TG2 functions as a deamidase, GTPase, isopepti
Externí odkaz:
https://doaj.org/article/3ee9eea37e6545c2b5e25db5f47cbf23
Publikováno v:
Amino Acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8de27e58cd53f56391a7b0563f272799
https://doi.org/10.1007/s00726-023-03272-7
https://doi.org/10.1007/s00726-023-03272-7
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Relative intensity of 102 lipophilic metabolites detected using LC-TOFMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d83eaf62b69884a2d5438bd3db7773
https://doi.org/10.1158/1940-6207.22534729
https://doi.org/10.1158/1940-6207.22534729
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
The cells were seeded in 96 well plates 24 h before treatment with AA in the presence and absence of 10 μM ACR in DMEM containing 5% FBS. After 48 h, cell viability was determined using the Cell Counting Kit-8. Quantitative data normalized to EtOH c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237f594b7a25ac0aeec5617acafbff30
https://doi.org/10.1158/1940-6207.22534738
https://doi.org/10.1158/1940-6207.22534738
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
The relative quantities of the detected metabolites involved in glycolysis/glyconeogenesis (A), the urea cycle (B), pyrimidine metabolism (C), amino acid metabolism (D), and nicotinate and nicotinamide metabolism (E) are represented as bar graphs (fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cb744813b01003684700fd0f1eb083
https://doi.org/10.1158/1940-6207.22534726
https://doi.org/10.1158/1940-6207.22534726
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Acyclic retinoid (ACR) is a promising drug under clinical trials for preventing recurrence of hepatocellular carcinoma. The objective of this study was to gain insights into molecular basis of the antitumorigenic action of ACR from a metabolic point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6e50cda6038be4923a0aa8e53820e5
https://doi.org/10.1158/1940-6207.c.6547624.v1
https://doi.org/10.1158/1940-6207.c.6547624.v1
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Relative intensity of 254 cationic metabolites detected using CE-TOFMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97780b7933f87a9308c115947f02af9c
https://doi.org/10.1158/1940-6207.22534732.v1
https://doi.org/10.1158/1940-6207.22534732.v1