Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kiyoshige Saito"'
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 128:495-501
The proliferative effects of endothelin-1 (ET-1), both alone and in combination with epidermal growth factor (EGF), and the effect of nitric oxide (NO) on the cell proliferation were investigated in cultured guinea pig bronchial smooth muscle cells.
Autor:
Keishi Iwamoto, Yasuo Kizawa, Tadashi Kusama, Hajime Murakami, Masakazu Sano, Kiyoshige Saito, Kazuhiko Hayashi
Publikováno v:
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 126:123-128
We investigated whether angiotensin II (Ang II) and endothelin-1(ET-1) are involved in submandibular hypertrophy in response to repeated treatment with isoproterenol (ISO) in rats. The immunoreactive Ang II (IRAng II) and immunoreactive ET-1 (IRET-1)
Autor:
Shigeru Matsubara, Masami Osawa, Kiyoshige Saito, Hajime Murakami, Keishi Iwamoto, Yasuo Kizawa, Masakazu Sano
Publikováno v:
Biological and Pharmaceutical Bulletin. 23:1185-1188
We have characterized angiotensin II (Ang II) receptor subtypes on rat submandibular gland membranes using a radioligand binding assay. [3H]Ang II binding to the membrane fractions exhibited both high (Kd =0.08 nm, Bmax =2.19 fmol/mg protein) and low
Publikováno v:
The Japanese Journal of Physiology. 50:429-435
In a previous study, we showed that the protein kinase C (PKC) activator 4beta-phorbol 12-myristate 13-acetate (PMA) inhibited the gamma-aminobutyric acid (GABA)-gated currents in Xenopus oocytes expressing human rho1 GABA(C) receptors. To investigat
Publikováno v:
Europe PubMed Central
Changes in the immunoreactive ET-1 levels during the anaphylactic reaction of airway tissue from ovalbumin-sensitized guinea pigs were investigated. ET-1-immunoreactivity (ET-IR) was detected in the epithelial and smooth muscle layers of tracheal sec
Publikováno v:
General Pharmacology: The Vascular System. 22:691-694
1. A left atrium of guinea pig driven electrically was used as a test organ containing M2-cholinoceptors. 2. Concentration-response curves of carbachol and butyltrimethylammonium, muscarinic full agonists, were progressively inhibited by 10 and 30 mi
Publikováno v:
Japanese Journal of Pharmacology. 56:151-158
Publikováno v:
Biologicalpharmaceutical bulletin. 29(2)
The effects of dexamethasone and aminophylline on survival of Jurkat T-lymphocytic leukemia cells and HL-60 promyelocytic leukemia cells were investigated. Dexamethasone (10, 1000 nM) and aminophylline (1, 100 microM) induced apoptosis in Jurkat and
Publikováno v:
General pharmacology. 22(5)
1. A piece of rabbit ciliary body was mounted in organ bath and used as a test organ containing muscarine receptors. 2. A concentration response curve of carbachol was completely inhibited by a 50 min treatment of the smooth muscle preparation with p
Publikováno v:
Japanese Journal of Pharmacology. 82:259