Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kiyoshi Noguchi"'
Autor:
Kevin Kiyoshi Noguchi, Omar Hoseá Cabrera, Brant S. Swiney, Patricia Salinas-Contreras, Julie Kathryn Smith, Nuri B. Farber
Publikováno v:
Neurobiology of Disease, Vol 83, Iss , Pp 35-43 (2015)
The external granule layer (EGL) is a proliferative region that produces over 90% of the neurons in the cerebellum but can also malignantly transform into a cerebellar tumor called the medulloblastoma (the most common malignant brain tumor in childre
Externí odkaz:
https://doaj.org/article/06a4bef83cfe43aca33b7edc68ac1bcc
Autor:
Yoshiyuki Hayashi, Kiyoshi Noguchi
Publikováno v:
Journal of the Japanese Association for Petroleum Technology. 85:17-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91216097d23991be658260f80ced66b0
https://doi.org/10.3720/japt.85.17
https://doi.org/10.3720/japt.85.17
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives The helicase-primase inhibitor amenamevir (ASP2151) is a novel therapeutic agent which has been approved for the treatment of herpes zoster. The present study examined the pharmacokinetic profile of amenamevir in rodents and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ea8707d965fe23bb0088f1e6febf79
http://europepmc.org/articles/PMC6244745
http://europepmc.org/articles/PMC6244745
Autor:
Takeshi Nakamura, Kaori Takama, Dorien Groenendaal, Radboud van Trigt, Yoshiaki Ohtsu, Kiyoshi Noguchi, Akitsugu Takada
Publikováno v:
Chromatographia. 80:217-227
This is a case study of the difficulties caused by supersaturation of an analyte during the quantification of a drug in urine. To support the clinical development of the potent helicase–primase inhibitor ASP2151, we developed and validated simple a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a69f0116fd579e7559b692311f9c97c
https://doi.org/10.1007/s10337-016-3236-4
https://doi.org/10.1007/s10337-016-3236-4
Autor:
Yoshiaki Ohtsu, Kiyoshi Noguchi, Takuya Sonoda, Yoko Susaki, Yasuhisa Fukunaga, Toshifumi Tohda, Takafumi Iwatsubo
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:34-48
The potent and selective phosphodiesterase 4 inhibitor ASP3258 is a novel therapeutic agent for asthma and chronic obstructive pulmonary disease (COPD). After a single oral administration to rats, ASP3258 is rapidly absorbed with a bioavailability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5754a2e9c6312690bc7e40da9f7e4e
https://doi.org/10.1002/bdd.1921
https://doi.org/10.1002/bdd.1921
Publikováno v:
Biomedical Chromatography. 29:161-163
The potent phosphodiesterase 4 inhibitor ASP3258 contains a carboxylic acid moiety and a naphthyridine ring and is a novel therapeutic agent for asthma and chronic obstructive pulmonary disease. To support the drug development of ASP3258, we develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5220df8cc6843a3af69ca2376fe79c10
https://doi.org/10.1002/bmc.3262
https://doi.org/10.1002/bmc.3262
Autor:
Kiyoshi Noguchi, Yoshishige Suzuki, Tohru Oikawa, Masashi Shiraishi, Toshio Suzuki, Tomoyuki Sasaki
Publikováno v:
IEEE Transactions on Magnetics. 46:1436-1439
We demonstrate the evidence of electrical spin injection into silicon (Si) using the Fe/MgO tunnel barrier by the following two methods: 1) non-local (NL) four-terminal magnetoresistance (MR) scheme with their respective corresponding ferromagnetic (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42be62020a17bcf9f4ba6d6a1747e4d5
https://doi.org/10.1109/tmag.2010.2045347
https://doi.org/10.1109/tmag.2010.2045347
Autor:
Toshiyuki Ayukawa, Tsutom Chou, Koji Shimazawa, Takahiko Machita, Tsuyoshi Ichiki, Disuke Miyauchi, Tomohito Mizuno, Kiyoshi Noguchi, Yoshihiro Tsuchiya, Shinji Hara
Publikováno v:
IEEE Transactions on Magnetics. 46:1487-1490
A new type of CPP-GMR film, which has ZnO-based novel spacer, was studied. A high MR ratio of 21.4% at RA of about 0.2 ??m2 at room temperature was obtained by optimization of the fabrication condition of ZnO layer. Based on HRTEM observation, the Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::622b27fd0f06388512e48b6a8279b5d0
https://doi.org/10.1109/tmag.2010.2042574
https://doi.org/10.1109/tmag.2010.2042574
Autor:
Hidetaka Kamimura, Takafumi Iwatsubo, K.-I. Umehara, Naoyuki Nakada, Takashi Usui, Kiyoshi Noguchi
Publikováno v:
Drug Metabolism and Disposition. 37:2137-2144
(−)- N -{2-[( R )-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel “funny” If current channel inhibitor, was being developed as a treatment for stable angina and atrial fibrillation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d350c0cfc0ae71d97b216f09d7b987
https://doi.org/10.1124/dmd.109.027813
https://doi.org/10.1124/dmd.109.027813
Autor:
K.-I. Umehara, Nobuaki Shirai, Hidetaka Kamimura, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui
Publikováno v:
Drug Metabolism and Disposition. 37:1646-1657
(-)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758) is a novel inhibitor of the "funny" If current channel (If channel) that is expressed in the sinus node of heart and is being develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6946fb150b03b68451199281388ba1fb
https://doi.org/10.1124/dmd.108.026294
https://doi.org/10.1124/dmd.108.026294