Zobrazeno 1 - 10 of 212 pro vyhledávání: '"Kiyoshi Miyai"'
1
HLA-A and -B antigens in Japanese patients with congenital hypothyroidism and their parents
Autor: Osamu Nose, T. Fukunishi, N. Amino, Kiyoshi Miyai, T Tsuruhara, H Mizuta
Publikováno v: Tissue Antigens. 23:210-216
The frequency of HLA-A and B antigens were studied in 32 Japanese patients with congenital hypothyroidism due to thyroid dysgenesis, and in their parents. The incidence of the Aw24 antigen was significantly higher in 27 mothers of patients with ectop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c94c5282bf987dc7944a0e11f17bb6
https://doi.org/10.1111/j.1399-0039.1984.tb00035.x
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2
Suppression of Thyroid Function during Ingestion of Seaweed 'Kombu' (Laminaria japonoca) in Normal Japanese Adults
Autor: Masahiko Kondo, Kiyoshi Miyai, Tomoyasu Tokushige
Publikováno v: Endocrine Journal. 55:1103-1108
The effect of ingesting seaweed "Kombu" (Laminaria japonica) on thyroid function was studied in normal Japanese adults. Ingesting 15 and 30 g of Kombu (iodine contents: 35 and 70 mg) daily for a short term (7-10 days) significantly increased serum th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e5122f9f5990f6336e18a1ff8541a5
https://doi.org/10.1507/endocrj.k08e-125
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4
Analysis of the Three Dimensional Structure of the CXGXC Motif in the CMGCC and CAGYC Regions of .ALPHA.-and .BETA.-Subunits of Human Chorionic Gonadotropin: Importance of Glycine Residue (G) in the Motif
Autor: Kiyoshi Miyai, Masami Kusunoki, Kengo Kinoshita
Publikováno v: Endocrine Journal. 53:51-58
The three dimensional structures of the C(1)X(2)G (3)(X(3))X(4)C(5) motif of hCG, which is considered to be important for noncovalent assembly of the alpha- and beta-subunits of glycoprotein hormones were analyzed to assess the importance of glycine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765c8abb722ef965b2fe0574c17326a8
https://doi.org/10.1507/endocrj.53.51
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5
Development of a radiotransporter assay for determination of iodide: preliminary studies
Autor: Seijiro Tsutsumi, Ke-ita Tatsumi, Takayuki Minekawa, Kiyoshi Miyai, Nobuyuki Amino
Publikováno v: Clinica Chimica Acta. 339:49-55
Background: The principle of the radiotransporter assay (RATRA) is that the concentration of the substance to be assayed (analyte) is determined by the degree of its competitive inhibition of the binding of radioactive analyte with transporter. Metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9a6bf89566d32ecbe83d1fdd3eb116
https://doi.org/10.1016/j.cccn.2003.09.011
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6
Evaluation of Highly Sensitive Thyrotropin Assay for Detecting Thyroid Diseases in Neonatal Screening: Preliminary Studies
Autor: Katsumi Taniguchi, Tomiko Miyagi, Hiroki Tatsumi, Nobuyuki Ashida, Kazutaka Inaoka, Shinobu Ida, Kiyoshi Miyai, Yoshihide Narizuka, Toshiaki Oura
Publikováno v: Endocrine Journal. 45:761-766
TSH concentrations in dried blood samples on filter paper were determined by a conventional enzyme-linked immunosorbent assay (ELISA), used for routine neonatal screening for primary hypothyroidism, and a highly sensitive bioluminescence ELISA (BL-EL
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7975f71876c272b4bf2fec5b6c86523f
https://doi.org/10.1507/endocrj.45.761
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7
Loss of biological activity due to Glu→Arg mutation at residue 11 of the B subunit of cholera toxin
Autor: Junichi Yamaoka, Yoshifumi Takeda, Hisao Kurazono, Shinji Yamasaki, Masatoshi Noda, Kiyoshi Miyai, Sadao Imamura
Publikováno v: Microbial Pathogenesis. 23:297-302
Since it has been reported that a single amino acid mutation of Gly→Arg in the CAGYC region of the β chain of human thyroid stimulating hormone (hTSH) was responsible for congenital isolated TSH deficiency, and that the same amino acid substitutio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8107bc7e9d640fa959930e8385026466
https://doi.org/10.1006/mpat.1997.0160
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9
Loss of biological activity of human chorionic gonadotropin (hCG) by the amino acid substitution on the 'CMGCC' region of the α-subunit
Autor: Masami Kusunoki, Naoko Nishikiori, Fumitaka Saji, T. Kikuchi, Kiyoshi Miyai, Tadashi Kimura, Osamu Tanizawa, T. Kimura, Masayasu Koyama, Chihiro Azuma
Publikováno v: Molecular and Cellular Endocrinology. 102:1-7
In order to study the bioactive sites of the glycoprotein hormones, we have prepared five point mutants on the CMGCC (Cys 28 -Met 29 -Gly 30 -Cys 31 -Cys 32 ) region of the human α-subunit by using site-directed mutagenesis. Each mutant human chorio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9d13c886c1d56179e08d65941e127b
https://doi.org/10.1016/0303-7207(94)90090-6
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10
Gestational thyrotoxicosis and hyperemesis gravidarum: possible role of hCG with higher stimulating activity
Autor: Eriko Ito, Kiyoshi Miyai, Nobuaki Mitsuda, Nobuyuki Amino, Haruo Tamaki, Motoko Kimura, Osamu Tanizawa
Publikováno v: Clinical Endocrinology. 38:345-350
Summary OBJECTIVE The thyroid gland is physiologically stimulated in normal early pregnancy. However, clinical thyrotoxicosis in normal pregnancy has not been well described. In order to clarify this we examined thyroid function and thyrotoxic sympto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2686aa4d0cea36b6a1b84223f70614bc
https://doi.org/10.1111/j.1365-2265.1993.tb00512.x
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