Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Kiyoshi Masuda"'
Autor:
Issei Imoto, Masako Saito, Kenichi Suga, Tomohiro Kohmoto, Masanobu Otsu, Keisuke Horiuchi, Hironao Nakayama, Shigeki Higashiyama, Mayumi Sugimoto, Ayumi Sasaki, Yukako Homma, Miki Shono, Ryuji Nakagawa, Yasunobu Hayabuchi, Shoichiro Tange, Shoji Kagami, Kiyoshi Masuda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract A disintegrin and metalloprotease 17 (ADAM17) is the major sheddase that processes more than 80 substrates, including tumour necrosis factor-α (TNFα). The homozygous genetic deficiency of ADAM17 causing a complete loss of ADAM17 expression
Externí odkaz:
https://doaj.org/article/f54d298d87a549a0b4eef6bb10764fdc
Autor:
Mitsuhiro Tsuboi, Kazuya Kondo, Kiyoshi Masuda, Shoichiro Tange, Koichiro Kajiura, Tomohiro Kohmoto, Hiromitsu Takizawa, Issei Imoto, Akira Tangoku
Publikováno v:
Cancer Medicine, Vol 8, Iss 9, Pp 4189-4199 (2019)
Abstract Background and Objectives In a previous genome‐wide screening, we identified hypermethylated CpG islands around glutamate decarboxylase 1 (GAD1) in lung adenocarcinoma (LADC). In this study, we aimed to investigate the methylation and expr
Externí odkaz:
https://doaj.org/article/f58723ba16434be4a37ee564d1ecd278
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1643 (2022)
Circular RNAs (circRNAs) comprise a large class of endogenous non-coding RNA with covalently closed loops and have independent functions as linear transcripts transcribed from identical genes. circRNAs are generated by a “back-splicing” process r
Externí odkaz:
https://doaj.org/article/9837c24c1ae7426f844b86f12b9d774d
Autor:
Tomohiro Kohmoto, Nana Okamoto, Takuya Naruto, Chie Murata, Yuya Ouchi, Naoko Fujita, Hidehito Inagaki, Shigeko Satomura, Nobuhiko Okamoto, Masako Saito, Kiyoshi Masuda, Hiroki Kurahashi, Issei Imoto
Publikováno v:
Molecular Cytogenetics, Vol 10, Iss 1, Pp 1-8 (2017)
Abstract Background Complex genomic rearrangements (CGRs) consisting of interstitial triplications in conjunction with uniparental isodisomy (isoUPD) have rarely been reported in patients with multiple congenital anomalies (MCA)/intellectual disabili
Externí odkaz:
https://doaj.org/article/407a5438f6fd40b9b765d03bdeb34368
Autor:
Daiju Fukuda, Sachiko Nishimoto, Kunduziayi Aini, Atsushi Tanaka, Tsuyoshi Nishiguchi, Joo‐ri Kim‐Kaneyama, Xiao‐Feng Lei, Kiyoshi Masuda, Takuya Naruto, Kimie Tanaka, Yasutomi Higashikuni, Yoichiro Hirata, Shusuke Yagi, Kenya Kusunose, Hirotsugu Yamada, Takeshi Soeki, Issei Imoto, Takashi Akasaka, Michio Shimabukuro, Masataka Sata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 7 (2019)
Background Toll‐like receptor (TLR) 9 recognizes bacterial DNA, activating innate immunity, whereas it also provokes inflammation in response to fragmented DNA released from mammalian cells. We investigated whether TLR9 contributes to the developme
Externí odkaz:
https://doaj.org/article/8f8f8329a3194984af6b247cbd40b84a
Autor:
Kei-ichi Morita, Takuya Naruto, Kousuke Tanimoto, Chisato Yasukawa, Yu Oikawa, Kiyoshi Masuda, Issei Imoto, Johji Inazawa, Ken Omura, Hiroyuki Harada
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0140480 (2015)
Gorlin syndrome (GS) is an autosomal dominant disorder that predisposes affected individuals to developmental defects and tumorigenesis, and caused mainly by heterozygous germline PTCH1 mutations. Despite exhaustive analysis, PTCH1 mutations are ofte
Externí odkaz:
https://doaj.org/article/d8231e1ecccc401b8d8fe230d74edf6c
Autor:
Manami Honda, Yuki Kuwano, Sakurako Katsuura-Kamano, Yoshiko Kamezaki, Kinuyo Fujita, Yoko Akaike, Shizuka Kano, Kensei Nishida, Kiyoshi Masuda, Kazuhito Rokutan
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75960 (2013)
MicroRNAs (miRNAs) play key roles in regulation of cellular processes in response to changes in environment. In this study, we examined alterations in miRNA profiles in peripheral blood from 25 male medical students two months and two days before the
Externí odkaz:
https://doaj.org/article/e43871082fa74864b1da13abbf0d2cbc
Autor:
Kiyoshi Masuda, Shigetada Teshima-Kondo, Mina Mukaijo, Naoko Yamagishi, Yoshiko Nishikawa, Kensei Nishida, Tomoko Kawai, Kazuhito Rokutan
Publikováno v:
PLoS Medicine, Vol 5, Iss 5, p e94 (2008)
BackgroundVascular endothelial growth factor-A (VEGF) is one of the key regulators of tumor development, hence it is considered to be an important therapeutic target for cancer treatment. However, clinical trials have suggested that anti-VEGF monothe
Externí odkaz:
https://doaj.org/article/2fb82b43a47c43e0b07742d512213682
Publikováno v:
Journal of Experimental Botany
Super-resolution microscopy revealed that the plant nuclear lamina proteins NMCP1 and NMCP2 organize into filamentous networks with filament bundles.
Plant genomes lack genes encoding intermediate filament proteins, including lamins; however, fu
Plant genomes lack genes encoding intermediate filament proteins, including lamins; however, fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07ef3b03b1c31617d3ba7c64283fb20
http://hdl.handle.net/2115/83451
http://hdl.handle.net/2115/83451
Publikováno v:
Polymer Journal. 53:1383-1391
Phenoxy-substituted phthalocyanine zinc (PPcZn) was synthesized and used as a photosensitizer to prepare a variety of self-disinfecting films by incorporating it into a cellulose acetate (CA) film at various concentrations. The generation of singlet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab857ad3929b4e588327dceea7d42c76
https://doi.org/10.1038/s41428-021-00532-9
https://doi.org/10.1038/s41428-021-00532-9