Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Kiyoshi Fukui"'
Autor:
Akira Nishi, Shusuke Numata, Atsushi Tajima, Xiaolei Zhu, Koki Ito, Atsushi Saito, Yusuke Kato, Makoto Kinoshita, Shinji Shimodera, Shinji Ono, Shinichiro Ochi, Akira Imamura, Naohiro Kurotaki, Shu-ichi Ueno, Nakao Iwata, Kiyoshi Fukui, Issei Imoto, Atsushi Kamiya, Tetsuro Ohmori
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Here we report de novo non-synonymous single-nucleotide variants (SNVs) by conducting whole exome sequencing of 18 trios consisting of Japanese patients with sporadic schizophrenia and their parents. Among nine SNVs, we explored the function
Externí odkaz:
https://doaj.org/article/2f03255fb4a14d7c9a0b4184ac4e7df3
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176544 (2017)
Human lysosomal-associated protein multispanning membrane 5 (LAPTM5) was identified by an ordered differential display-polymerase chain reaction (ODD-PCR) as an up-regulated cDNA fragment during 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced diff
Externí odkaz:
https://doaj.org/article/067aa2027cbb411292cd15308b72fd35
Autor:
Yusuke Kato, Kazuhiro Takahashi, Kiyoshi Fukui, Masakazu Mimaki, Kazuo Suzuki, Fuyu Ito, Shoichi Suzuki
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:3491-3500
We performed a neuraminidase sequence analysis of thirty-two pediatric patients with influenza B who visited Teikyo University Hospital from January 2016 to March 2017, and found oseltamivir-resistant samples belonging to the Yamagata and Victoria li
Autor:
Nobuo Maita, Niyada Hin, Kazuko Yorita, Camilo Rojas, Takashi Tsukamoto, Kiyoshi Fukui, Sumire Kurosawa, Barbara S. Slusher, Yusuke Kato, Ajit G. Thomas
Publikováno v:
European Journal of Medicinal Chemistry. 159:23-34
A series of thiophene-2-carboxylic acids and thiophene-3-carboxylic acids were identified as a new class of DAO inhibitors. Structure-activity relationship (SAR) studies revealed that small substituents are well-tolerated on the thiophene ring of bot
Autor:
Hayato Miyazaki, Wanitcha Rachadech, Yuji Shishido, Kiyoshi Fukui, Hirofumi Sogabe, Soo Hyeon Kim
Publikováno v:
Journal of biochemistry. 170(1)
D-amino acid oxidase (DAO) is a flavoenzyme catalyzing the oxidation of D-amino acid (AA)s. In the kidney, its expression is detected in proximal tubules, and DAO is considered to play a role in the conversion of D-form AAs to α-keto acids. LLC-PK1
Autor:
I. Shimomura, Kiyoshi Fukui, Sho Yoneda, H. Sho, Shuichi Toyoda, Junji Kozawa, Yukari Fujita, Hidetoshi Eguchi, Hitoshi Ozawa, Chisaki Ishibashi
Publikováno v:
Biochemical and biophysical research communications. 534
There have been several clinical reports of transient postoperative hyperglycemia in patients with insulinoma, but the effect of insulinoma on normal β-cells has not been investigated. We examined the glucose transporter 2 (GLUT2) and glucagon-like
P219L substitution in human D-amino acid oxidase impacts the ligand binding and catalytic efficiency
Autor:
Kazuko Yorita, Yuji Shishido, Nobuo Maita, Yusuke Kato, Hirofumi Sogabe, Kiyoshi Fukui, Wanitcha Rachadech, Soo Hyeon Kim, Rabab M. Abou El-Magd
Publikováno v:
Journal of biochemistry. 168(5)
Human D-amino acid oxidase (DAO) is a flavoenzyme that is implicated in neurodegenerative diseases. We investigated the impact of replacement of proline with leucine at Position 219 (P219L) in the active site lid of human DAO on the structural and en
Publikováno v:
Computational Biology and Chemistry. 74:94-104
Sirtuin4 (Sirt4) is one of the mammalian homologues of Silent information regulator 2 (Sir2), which promotes the longevity of yeast, C. elegans, fruit flies and mice. Sirt4 is localized in the mitochondria, where it contributes to preventing the deve
Autor:
Shuji Moriyama, Yusuke Shintani, Masahito Kikuchi, Yoshikazu Minegishi, Ayako Tanno, Kiyoshi Fukui, Jun Kitahori, Moyu Seike
Publikováno v:
AIJ Journal of Technology and Design. 24:223-228
Autor:
Yusuke Kato1, Kiyoshi Fukui1 kiyo.fukui@tokushima-u.ac.jp
Publikováno v:
Journal of Biochemistry. Feb2017, Vol. 161 Issue 2, p223-230. 8p.