Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Kiyoshi Teshigawara"'
Autor:
Shangze Gao, Keyue Liu, Wenhan Ku, Dengli Wang, Hidenori Wake, Handong Qiao, Kiyoshi Teshigawara, Masahiro Nishibori
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundSystemic allergic reaction is characterized by vasodilation and vascular leakage, which causes a rapid, precipitous and sustained decrease in arterial blood pressure with a concomitant decrease of cardiac output. Histamine is a major mediat
Externí odkaz:
https://doaj.org/article/06baff4c847041e2970f63e84640730a
Autor:
Dengli Wang, Daiki Ousaka, Handong Qiao, Ziyi Wang, Kun Zhao, Shangze Gao, Keyue Liu, Kiyoshi Teshigawara, Kenzo Takada, Masahiro Nishibori
Publikováno v:
Cells, Vol 11, Iss 19, p 2970 (2022)
Intracerebral hemorrhage (ICH) is recognized as a severe clinical problem lacking effective treatment. High mobility group box-1 (HMGB1) exhibits inflammatory cytokine-like activity once released into the extracellular space from the nuclei. We previ
Externí odkaz:
https://doaj.org/article/7547c60c872b42eb8e2d70acbab9a76e
Autor:
Shangze Gao, Hidenori Wake, Masakiyo Sakaguchi, Dengli Wang, Youhei Takahashi, Kiyoshi Teshigawara, Hui Zhong, Shuji Mori, Keyue Liu, Hideo Takahashi, Masahiro Nishibori
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101180- (2020)
Summary: High-mobility group box-1 (HMGB1) protein has been postulated to play a pathogenic role in severe sepsis. Histidine-rich glycoprotein (HRG), a 75 kDa plasma protein, was demonstrated to improve the survival rate of septic mice through the re
Externí odkaz:
https://doaj.org/article/d3f4eb5f6ad24dcf9a69fdcaf5929f7c
Autor:
Soe Soe Htwe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Barbara S. Stonestreet, Yow-Pin Lim, Masahiro Nishibori
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1923-1934 (2018)
Abstract: The plasma levels of inter-α inhibitor proteins (IAIPs) are decreased in patients with sepsis and the reduced levels correlate with increased mortality. In the present study, we examined the effects of IAIPs on human neutrophils to better
Externí odkaz:
https://doaj.org/article/27a4408ce4014aa6b882758e7455a067
Autor:
Hui Zhong, Hidenori Wake, Keyue Liu, Yuan Gao, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Shuji Mori, Masahiro Nishibori
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 3, Pp 97-106 (2018)
The apoptotic process of erythrocytes is known as eryptosis, and is characterized by phosphatidylserine (PS) expression on the outer membrane. PS-positive erythrocytes are increased in sepsis, and PS is believed to facilitate coagulation of erythrocy
Externí odkaz:
https://doaj.org/article/fb25742335bb4b92bf1cbd9ad0bd3bf2
Autor:
Yuta Morioka, Kiyoshi Teshigawara, Yasuko Tomono, Dengli Wang, Yasuhisa Izushi, Hidenori Wake, Keyue Liu, Hideo Kohka Takahashi, Shuji Mori, Masahiro Nishibori
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 4, Pp 218-224 (2017)
Advanced glycation end-products (AGEs) are produced by non-enzymatic glycation between protein and reducing sugar such as glucose. Although glyceraldehyde-derived AGEs (Glycer-AGEs), one of the AGEs subspecies, have been reported to be involved in th
Externí odkaz:
https://doaj.org/article/6371cd4566124121ba30f92eec0ab686
Autor:
Li Fu, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Tadashi Yoshino, Hideo Takahashi, Shuji Mori, Masahiro Nishibori
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Inflammatory processes in brain tissue have been described in human epilepsy of various etiologies and in experimental models of seizures. High mobility group box-1 (HMGB1) is now recognized as representative of damage-associated molecular p
Externí odkaz:
https://doaj.org/article/6df81a8a50254fc58a102a06ba381d8b
Autor:
Hidenori Wake, Shuji Mori, Keyue Liu, Yuta Morioka, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Kosuke Kuroda, Yuan Gao, Hideo Takahashi, Aiji Ohtsuka, Tadashi Yoshino, Hiroshi Morimatsu, Masahiro Nishibori
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 180-194 (2016)
Sepsis is a major cause of death worldwide. We show that a plasma protein histidine-rich glycoprotein (HRG) was decreased significantly in septic mice with cecal ligation and puncture (CLP) and supplementary treatment of septic mice with exogenous HR
Externí odkaz:
https://doaj.org/article/8838bbc23de14904aca97aae31ed44e8
Autor:
Yasuhisa Izushi, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Hidenori Wake, Katsuyoshi Takata, Tadashi Yoshino, Hideo Kohka Takahashi, Shuji Mori, Masahiro Nishibori
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 4, Pp 226-234 (2016)
Acute respiratory distress syndrome (ARDS) is a severe respiratory failure caused by acute lung inflammation. Recently, the receptor for advanced glycation end-products (RAGE) has attracted attention in the lung inflammatory response. However, the fu
Externí odkaz:
https://doaj.org/article/4e81e7d0b4ce46bfb15edc16b8d20131
Autor:
Dengli Wang, Keyue Liu, Yusuke Fukuyasu, Kiyoshi Teshigawara, Li Fu, Hidenori Wake, Aiji Ohtsuka, Masahiro Nishibori
Publikováno v:
Cells, Vol 9, Iss 3, p 643 (2020)
High mobility group box-1 (HMGB1), a nonhistone chromatin DNA-binding protein, is released from neurons into the extracellular space under ischemic, hemorrhagic, and traumatic insults. However, the details of the time-dependent translocation of HMGB1
Externí odkaz:
https://doaj.org/article/1c971c81e5d04449aed3253dfce8254e