Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kiyoshi, Nose"'
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus vi
Externí odkaz:
https://doaj.org/article/6023ca48c1164cb097d033a3bffa8c19
Autor:
Kazunori Mori, Motoko Shibanuma, Yukiko Oshima, Hiroyuki Hamanaka, Kiyoshi Nose, Fumihiro Ishikawa, Yuri Araki
Publikováno v:
Journal of Biological Chemistry. 287:38854-38865
Anchorage loss elicits a set of responses in cells, such as transcriptional changes, in order to prevent inappropriate cell growth in ectopic environments. However, the mechanisms underlying these responses are poorly understood. In this study, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b1e570384c779b00a27c1fdf179a9c
https://doi.org/10.1074/jbc.m112.377721
https://doi.org/10.1074/jbc.m112.377721
Publikováno v:
International Journal of Cell Biology
International Journal of Cell Biology, Vol 2012 (2012)
International Journal of Cell Biology, Vol 2012 (2012)
HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d6ea039a5aaad659c83ef919a4799f
https://doi.org/10.1155/2012/426138
https://doi.org/10.1155/2012/426138
Autor:
Tetsu Uchida, Kazunori Mori, Fumihiro Ishikawa, Kyota Ushida, Motoko Shibanuma, Anna Inoue, Kiyoshi Nose
Publikováno v:
Free Radical Research. 45:672-680
Mitochondria are considered to play an important role in oxidative stress response since they are a source of reactive oxygen species and are also targeted by these species. This study examined the mitochondrial conditions in cells of epithelial orig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc84dd0a1df6e740bf51df4f4ca70f3
https://doi.org/10.3109/10715762.2011.564169
https://doi.org/10.3109/10715762.2011.564169
Publikováno v:
Oncogene. 29:909-919
Transforming growth factor (TGF)-beta regulates the expression of matrix metalloproteinases (MMPs) and components of the extracellular matrix, thereby profoundly affecting the microenvironment of cells including cancerous ones. We studied MMP-10 indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cff2eec01e312f681afb39065149a3
https://doi.org/10.1038/onc.2009.387
https://doi.org/10.1038/onc.2009.387
Autor:
Motoko Shibanuma, Takashi Akimoto, Kazunori Mori, Yuri Araki, Haruka Yamamoto, Kiyoshi Nose, Hidetoshi Hayashi, Toshihiko Yoshie, Fumihiro Ishikawa
Publikováno v:
Journal of Biochemistry. 146:123-132
Mitochondrial dysfunction, in particular, interference in the respiratory chain, is often responsible for the toxicogenic effects of xenobiotics. In this study, changes in gene expression resulting from pharmacological inhibition of the respiratory c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cfa7cc5b968326f684adb167243353
https://doi.org/10.1093/jb/mvp052
https://doi.org/10.1093/jb/mvp052
Autor:
Motoko Shibanuma, Yosuke Toya, Etsuko Hirao, Yukiko Oshima, Kiyoshi Nose, Kazunori Mori, Fumihiro Ishikawa
Publikováno v:
Molecular Biology of the Cell. 20:218-232
Anchorage dependence of cell growth and survival is a critical trait that distinguishes nontransformed cells from transformed cells. We demonstrate that anchorage dependence is determined by anchorage-dependent nuclear retention of cyclin D1, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fec014926a5ac4e91ad741e92d1f054
https://doi.org/10.1091/mbc.e08-04-0428
https://doi.org/10.1091/mbc.e08-04-0428
Autor:
Motoko Shibanuma, Nanae Wachi, Soichiro Enomoto, Joo-ri Kim-Kaneyama, Keitatsu Koh, Masataka Sata, Kiyoko Fukabori, Kiyoshi Nose
Publikováno v:
Biochemical and Biophysical Research Communications. 376:682-687
Focal adhesion components are targets for biochemical and mechanical stimuli that evoke crucial injury. Hic-5 (hydrogen peroxide-inducible clone 5) is a multidomain adaptor protein which is implicated in the regulation of integrin signaling in focal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3ccf64a2ca8ef5d44cf525084e0d8b
https://doi.org/10.1016/j.bbrc.2008.09.051
https://doi.org/10.1016/j.bbrc.2008.09.051
Publikováno v:
Experimental Cell Research. 314:2131-2140
We found that a specific isoform of hepatocyte nuclear factor 4alpha (HNF-4alpha), HNF-4alpha8, was expressed in mouse mammary epithelial NMuMG cells, and that its expression was repressed by TGF-beta. The repression was interfered by dominant negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1aa2b237c85125304aa007c4d12755
https://doi.org/10.1016/j.yexcr.2008.03.013
https://doi.org/10.1016/j.yexcr.2008.03.013
Autor:
Takuya Watanabe, Tetsuo Sakai, Shinji Koba, Tomoko Kanome, Kae Nishio, Kiyoshi Nose, Akira Miyazaki, Shigeki Hongo, Masayoshi Shichiri, Hidekazu Ota, Kengo Sato, Takashi Katagiri, Youichi Kobayashi, Taka-aki Matsuyama
Publikováno v:
Circulation. 117:638-648
Background— Human salusins, related bioactive polypeptides with mitogenic effects on vascular smooth muscle cells and fibroblasts and roles in hemodynamic homeostasis, may be involved in the origin of coronary atherosclerosis. Macrophage foam cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199d60a5c4478b0f92f6064a20c90bcf
https://doi.org/10.1161/circulationaha.107.712539
https://doi.org/10.1161/circulationaha.107.712539