Nanoscale organization is changed in native, surface AMPARs by mouse brain region and tauopathy.

Autor: Vaidya RM; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Zhang J; Dept. of Physics, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Nall D; Dept. of Physics, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Lee Y; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Chang Kim E; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Ma D; Weldon School of Biomedical Engineering, Purdue University; West Lafayette, IN, 47907, USA., Huang F; Weldon School of Biomedical Engineering, Purdue University; West Lafayette, IN, 47907, USA., Nonaka H; Department of Synthetic Chemistry and Biological Chemistry, Kyoto University; 615-8510, Kyoto, Japan., Kiyonaka S; Department of Biomolecular Engineering, Nagoya University; Nagoya, 464-8603, Japan., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Kyoto University; 615-8510, Kyoto, Japan., Jung Chung H; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA., Selvin PR; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA.; Dept. of Physics, University of Illinois at Urbana-Champaign; Urbana, IL, 61801, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 23. Date of Electronic Publication: 2024 Jul 23.

Bioorthogonal chemical labeling of endogenous neurotransmitter receptors in living mouse brains.

Autor: Nonaka H; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan., Sakamoto S; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan., Shiraiwa K; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Ishikawa M; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan., Tamura T; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan., Okuno K; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Kondo T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Kiyonaka S; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan.; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Susaki EA; Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka 565-5241, Japan., Shimizu C; Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka 565-5241, Japan., Ueda HR; Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka 565-5241, Japan.; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan., Kakegawa W; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan.; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Arai I; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Yuzaki M; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Hamachi Innovative Molecular Technology for Neuroscience, Exploratory Research for Advanced Technology, Japan Science and Technology Agency, Kyoto 615-8530, Japan.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 06; Vol. 121 (6), pp. e2313887121. Date of Electronic Publication: 2024 Jan 31.

Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue.

Autor: Ojima K; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan.; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Kakegawa W; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Yamasaki T; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Miura Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Itoh M; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Michibata Y; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Kubota R; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Miura E; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Nonaka H; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan., Takahashi S; Laboratory Animal Resource Center in Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan., Yuzaki M; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan. myuzaki@keio.jp., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan. ihamachi@sbchem.kyoto-u.ac.jp., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan. kiyonaka@chembio.nagoya-u.ac.jp.; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Nagoya, 464-8603, Japan. kiyonaka@chembio.nagoya-u.ac.jp.

Publikováno v: Nature communications [Nat Commun] 2022 Jun 16; Vol. 13 (1), pp. 3167. Date of Electronic Publication: 2022 Jun 16.

Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes.

Autor: Nonaka H; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan., Mino T; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Sakamoto S; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Oh JH; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan., Watanabe Y; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Ishikawa M; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan., Tsushima A; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Amaike K; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan., Kiyonaka S; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan.; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Tamura T; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan., Aricescu AR; Division of Structural Biology, University of Oxford, Oxford OX3 7BN, UK.; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Kakegawa W; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan.; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Miura E; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Yuzaki M; Department of Neurophysiology, Keio University School of Medicine, Tokyo 160-8582, Japan., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo 102-0075, Japan.

Publikováno v: Chem [Chem] 2023 Feb; Vol. 9 (2), pp. 523-540.

Orthogonal Activation of Metabotropic Glutamate Receptor Using Coordination Chemogenetics.

Autor: Senoo A; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Yamada Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Ojima K; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan.; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan.; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo, Japan., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan.

Publikováno v: Frontiers in chemistry [Front Chem] 2022 Jan 14; Vol. 9, pp. 825669. Date of Electronic Publication: 2022 Jan 14 (Print Publication: 2021).