Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kiyomi Kasai-Eguchi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59385 (2013)
Exposure of hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation causes a marked suppression of mature functional blood cell production in a linear energy transfer (LET)- and/or dose-dependent manner. However, little information about LE
Externí odkaz:
https://doaj.org/article/ef460b17674f4574b1c424245222cd97
Publikováno v:
Radiation Research. 176(1):8-16
Hematopoietic processes, especially megakaryocytopoiesis and thrombopoiesis, are highly sensitive to high-linear energy transfer (LET) radiations such as heavy-ion beams that have greater biological effects than low-LET radiation. This study examined
Autor:
Ken Itoh, Kenji Takahashi, Ikuo Kashiwakura, Hironori Yoshino, Satoru Monzen, Atsushi Maruyama, Kiyomi Kasai-Eguchi, Yoshinao Abe
Publikováno v:
Journal of Radiation Research. 50:477-486
Heavy ion beams are a high-LET radiation that has greater biological effect than electron beams or X-rays. However, little is known about the effect of heavy ion beams on the proliferation and differentiation of human hematopoietic stem/progenitor ce
Autor:
Teruyo Tsukada, Hirotake Yamaguchi, Fumio Yatagai, Toshihiro Kurobe, Kenichi Masumura, Kiyomi Kasai-Eguchi, Takehiko Nohmi, Nobuhisa Fukunishi
Publikováno v:
Environmental and Molecular Mutagenesis. 40:216-225
The influence of the loss of p53 gene on heavy-ion-induced mutations was examined by constructing a new line of transgenic mice, p53 knockout (p53(-/-)) gpt delta. In this mouse model, deletions in lambda DNA integrated into the mouse genome are pref
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59385 (2013)
PLoS ONE
PLoS ONE
Exposure of hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation causes a marked suppression of mature functional blood cell production in a linear energy transfer (LET)- and/or dose-dependent manner. However, little information about LE
Autor:
Kiyomi Kasai-Eguchi, Naoto Tatewaki, Hiroshi Nishida, Nobuo Ikekawa, Yuki Nakajima, Kazunori Anzai, Kayoko Nakayama-Kawakami, Tetsuya Konishi
Publikováno v:
Cancer Research. 70:3873-3873
ATM (Ataxia Telangiectasia Mutated) protein kinase plays a crucial role in cellular DNA damage responses. The inhibition of ATM leads to an abolishment of one such signal pathways termed as “checkpoints”. It is expected that the discovery of chec