Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kiyoko S. Kanba"'
Autor:
S.T. MacKey, Soichiro Nomura, Michael McKinney, Lori Enloes, Kiyoko S. Kanba, Robert T. Abraham, Shigenobu Kanba, Elliott Richelson, Michael A. Pfenning
Publikováno v:
Biochemical Pharmacology. 40:1005-1014
Acute desensitization of M 1 muscarinic receptor-mediated responses (cyclic GMP formation and inositol phosphate release) was studied in murine neuroblastoma cells (N1E-115 clone). After a 45-min incubation at 37° of N1E-115 cells either in monolaye
Autor:
Nayef R.F. Al-Rodhan, Kiyoko S. Kanba, Judith A. Gilbert, Elliott Richelson, Al Nelson, Michael A. Pfenning, Daniel J. McCormick, Tony L. Yaksh, Eric W. Larson
Publikováno v:
Brain research. 557(1-2)
Neurotensin, an endogenous tridecapeptide, produces a potent, naloxone-insensitive antinociceptive response when it is microinjected into the periaqueductal gray region of the rat brainstem. In the present study, the ED50 for neurotensin in inducing
Publikováno v:
Journal of Neurochemistry. 46:946-952
The binding of [3H]neurotensin to membranes from human brain at 0 degrees C was specific, saturable, and reversible. In the frontal cortex, the equilibrium dissociation constant (KD) for [3H]neurotensin determined from the ratio of rate constants (k-
Autor:
Kiyoko S. Kanba, Elliott Richelson
Publikováno v:
Biochemical Pharmacology. 36:869-874
Neurotensin, some of its analogs, and neuromedin N were examined for comparison of their potencies at stimulating inositol phospholipid hydrolysis and cyclic GMP synthesis in intact murine neuroblastoma cells (clone N1E-115). Neurotensin(8-13) and ac
Publikováno v:
European journal of pharmacology. 126(1-2)
The effect of lithium ion (Li + ) on receptor-mediated synthesis of cyclic GMP, a putative second messenger, was examined using intact murine neuroblastoma cells (clone N1E-115). Lithium chloride potently inhibited cyclic GMP formation stimulated by
Publikováno v:
European journal of pharmacology. 125(1)
Autor:
Elliott Richelson, Kiyoko S. Kanba, Andrew G. Moore, Lori J. Enloe, Daniel J. McCormick, Judith A. Gilbert, Michael A. Pfenning
Publikováno v:
Biochemical pharmacology. 38(19)
Neurotensin(8-13), the carboxyl-terminal portion of neurotensin, is 4-50 times more potent than native neurotensin in binding to intact neuroblastoma N1E-115 cells and human brain tissue and in stimulation of intracellular cyclic GMP production and i