Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Kiyoko Kaneko"'
Autor:
Nourin Jahan, Hiroyuki Ohsaki, Kiyoko Kaneko, Asadur Rahman, Takeshi Nishiyama, Makoto Koizumi, Shuichiro Yamanaka, Kento Kitada, Yuki Sugiura, Kenji Matsui, Takashi Yokoo, Takayuki Hamano, Makoto Kuro-o, Takuya Itou, Miwa Suzuki, Keiichi Ueda, Akira Nishiyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract This study aimed to investigate whether phosphate contributes to the pathogenesis of chronic kidney disease (CKD) in dolphins. Renal necropsy tissue of an aged captive dolphin was analyzed and in vitro experiments using cultured immortalized
Externí odkaz:
https://doaj.org/article/012b64be875745bba67c6ca815f50a15
Autor:
Meika Kaneko, Yoshie Reien, Hanae Morio, Tomoko Fukuuchi, Kiyoko Kaneko, Yuri Hirayama, Hirofumi Hashimoto, Nobuyo Kuwata, Hiroaki Mitsuya, Naohiko Anzai
Publikováno v:
Journal of Pharmacological Sciences, Vol 146, Iss 2, Pp 82-87 (2021)
Islatravir (ISL; 4′-ethynyl-2-fluoro-2′-deoxyadenosine or EFdA) is a novel reverse transcriptase translocation inhibitor and has a unique structure and high antiviral activity against wild-type and multidrug resistant HIV strains. In this study,
Externí odkaz:
https://doaj.org/article/deb28ae4db7b4daa9949cb6f60537b96
Autor:
Takanori Watanabe, Mariko Ishikawa, Kohtaro Abe, Tomohito Ishikawa, Satomi Imakiire, Kohei Masaki, Kazuya Hosokawa, Tomoko Fukuuchi, Kiyoko Kaneko, Toshio Ohtsubo, Mayumi Hirano, Katsuya Hirano, Hiroyuki Tsutsui
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021)
Background Recent studies have demonstrated that uric acid (UA) enhances arginase activity, resulting in decreased NO in endothelial cells. However, the role of lung UA in pulmonary arterial hypertension (PAH) remains uncertain. We hypothesized that
Externí odkaz:
https://doaj.org/article/9ad292f107d744b79f479490be41805d
Publikováno v:
Pharmaceuticals, Vol 6, Iss 11, Pp 1347-1360 (2013)
In mammals, excess purine nucleosides are removed from the body by breakdown in the liver and excretion from the kidneys. Uric acid is the end product of purine metabolism in humans. Two-thirds of uric acid in the human body is normally excreted thro
Externí odkaz:
https://doaj.org/article/6181dec003e74d40950091cad84703de
Autor:
Shunya Uchida, Wen Xiu Chang, Tatsuru Ota, Yoshifuru Tamura, Takeshi Shiraishi, Takanori Kumagai, Shigeru Shibata, Yoshihide Fujigaki, Makoto Hosoyamada, Kiyoko Kaneko, Zhong Yang Shen, Shin Fujimori
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145506 (2015)
The role of uric acid (UA) in the progression of chronic kidney disease (CKD) remains controversial due to the unavoidable cause and result relationship. This study was aimed to clarify the independent impact of UA on the subsequent risk of end-stage
Externí odkaz:
https://doaj.org/article/4bf885e806ed43fab6f887374b047197
Autor:
Fukue, Takayanagi, Takuya, Uchino, Natsumi, Motoki, Kanae, Uchida, Hitomi, Asakura, Kiyoko, Uno-Eder, Takahiro, Nomura, Kazuhisa, Tsukamoto, Tomoko, Fukuuchi, Noriko, Yamaoka, Kiyoko, Kaneko
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 41:1296-1304
Hospital meals are prepared with the nutrients required by the patient's medical condition in consideration. However, no research on the purine content of hospital meals has been conducted, and it is not shown on the purine content. The recommended p
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 41:1287-1295
In this study, we determined the purine contents in milk and soymilk, as protein-rich drinks, and in enteral nutritional supplements employed to ameliorate protein malnutrition in the elderly. Milk consumption is known to lower serum uric acid levels
Xanthinuria Type 1 with a Novel Mutation in Xanthine Dehydrogenase and a Normal Endothelial Function
Autor:
Satoshi, Miyazaki, Toshihiro, Hamada, Shinobu, Sugihara, Einosuke, Mizuta, Yusuke, Endo, Akira, Ohtahara, Koji, Komatsu, Masanari, Kuwabara, Tomoko, Fukuuchi, Kiyoko, Kaneko, Kimiyoshi, Ichida, Kazuhide, Ogino, Haruaki, Ninomiya, Kazuhiro, Yamamoto, Takashi, Nakamura, Ichiro, Hisatome
Publikováno v:
Internal Medicine. 61:1383-1386
Whether or not extremely low levels of serum uric acid (SUA) in xanthinuria are associated with impairment of the endothelial function and exercise-induced acute kidney injury (EIAKI) is unclear. A 59-year-old woman without EIAKI or urolithiasis had
Autor:
Hiroyuki Ohsaki, Kiyoko Kaneko, Asadur Rahman, Takeshi Nishiyama, Makoto Koizumi, Shuichiro Yamanaka, Kento Kitada, Yuki Sugiura, Kenji Matsui, Takashi Yokoo, Takayuki Hamano, Makoto Kuro-o, Takuya Itou, Miwa Suzuki, Keiichi Ueda, Akira Nishiyama, Nourin Jahan
Publikováno v:
Scientific Reports. 13
This study aimed to investigate whether phosphate contributes to the pathogenesis of chronic kidney disease (CKD) in dolphins. Renal necropsy tissue of an aged captive dolphin was analyzed and in vitro experiments using cultured immortalized dolphin
Autor:
Hiroaki Mitsuya, Hirofumi Hashimoto, Hanae Morio, Meika Kaneko, Nobuyo Kuwata, Yuri Hirayama, Tomoko Fukuuchi, Kiyoko Kaneko, Naohiko Anzai, Yoshie Reien
Publikováno v:
Journal of Pharmacological Sciences, Vol 146, Iss 2, Pp 82-87 (2021)
Islatravir (ISL; 4'-ethynyl-2-fluoro-2'-deoxyadenosine or EFdA) is a novel reverse transcriptase translocation inhibitor and has a unique structure and high antiviral activity against wild-type and multidrug resistant HIV strains. In this study, we i