Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kiyoko Bando"'
Autor:
Yukari Fujiwara, Dong-sik Ham, Byung Hyune Choi, Yat P. Tsui, James Ooi, Yoshie Tsurumaki, Tomohiro Yoneda, Feng-Cheng Chou, Pawan Gupta, Yongjun Liu, Takeshi Watanabe, Joo Y. Lee, Yuu Moriya, Yoshiteru Kamiyama, Chih-Yuan Ho, Kou Omura, Ling-Mei Wang, Kiyoko Bando, Guangyang Liu, Yohan Bae, Masayuki Kanki, Hiroshi Karasawa
Publikováno v:
Cytotherapy. 23:874-885
Background aims Cell-based regenerative medicine is an innovative field that can potentially alter the overall survival and quality of life of patients with devastating diseases. Several cell therapy products (CTPs) have been approved within the last
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec5ced7926e933272f9d5b65367bad1
https://doi.org/10.1016/j.jcyt.2021.04.007
https://doi.org/10.1016/j.jcyt.2021.04.007
Autor:
Tomohiro Yoneda, Toshimitsu Tanaka, Kiyoko Bando, Byung Hyune Choi, Ryan Chang, Yukari Fujiwara, Pawan Kumar Gupta, Dong-sik Ham, Hiroshi Karasawa, Shinobu Kuwae, Shing-mou Lee, Yuu Moriya, Koji Takakura, Yoshie Tsurumaki, Takeshi Watanabe, Keiji Yoshimura, Masayuki Nomura
Publikováno v:
Cytotherapy. 24(9)
The 4th Asia Partnership Conference of Regenerative Medicine (APACRM) was held online on April 15, 2021, to promote regulatory harmonization of regenerative medicine products throughout Asia. Recognizing domestic regulatory guidelines within each cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c084fd7254f1b46d2a802cea8a5ffcbc
https://pubmed.ncbi.nlm.nih.gov/35193824
https://pubmed.ncbi.nlm.nih.gov/35193824
Autor:
Akihiko Kiyoshi, Isao Shimizu, Yasunori Katsura, Tadashi Tsubouchi, Kiyoko Bando, Seiko Oku, Shinji Tsujimoto, Toru Yamada, Kazuhiro Chihara, Yukiko Mine, Takeshi Kunimatsu
Publikováno v:
European Journal of Pharmacology. 826:96-105
The pharmacological activity of DSP-6952, a novel compound was investigated, compared to that of clinically efficacious gastrointestinal (GI) prokinetic 5-hydroxytryptamine 4 (5-HT 4 ) receptor agonists. DSP-6952 had a strong affinity of K i = 51.9 n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840f70dc774d7cf9b312025373d5c8ab
https://doi.org/10.1016/j.ejphar.2018.02.037
https://doi.org/10.1016/j.ejphar.2018.02.037
Autor:
Eiichiro Ogimura, Tetsuya Nakagawa, Mayuko Tokizono, Kousei Ito, Shuichi Sekine, Kiyoko Bando
Publikováno v:
Journal of Pharmaceutical Sciences. 106:2509-2514
We previously reported a cell-based toxicity assay using sandwich-cultured hepatocytes in combination with a titrated amount of human bile acid (BA) species. In this assay, test compound-induced inhibition of BA efflux from sandwich-cultured hepatocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d2b7f3a9e30fe03134740077f5d1d1
https://doi.org/10.1016/j.xphs.2017.04.050
https://doi.org/10.1016/j.xphs.2017.04.050
Autor:
Toru Yamada, Izumi Matsumoto, Mami Kouchi, Yuta Fujii, Tomoaki Tochitani, Izuru Miyawaki, Akihito Yamashita, Kiyoko Bando
Publikováno v:
Toxicologic Pathology. 45:756-763
The aim of this study was to evaluate the usefulness of simultaneous measurement of plasma steroids, including precursors, for the evaluation of drug effects on adrenal steroidogenesis in vivo. Plasma concentrations of corticosterone and its precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f409c10f5d90e848d629e13ed774f8d1
https://doi.org/10.1177/0192623317730416
https://doi.org/10.1177/0192623317730416
Publikováno v:
Toxicological Sciences. 158:347-355
Troglitazone and pioglitazone were developed as thiazolidinedione-type antidiabetes drugs, but only troglitazone was withdrawn from the markets due to severe liver injury. As both troglitazone and its sulfate metabolite are strong inhibitors of the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2719ef54ab7aff64ec6ca40f24b388
https://doi.org/10.1093/toxsci/kfx091
https://doi.org/10.1093/toxsci/kfx091
Publikováno v:
The Journal of Toxicological Sciences. 42:519-527
Monitoring dramatic changes in intracellular calcium ion levels during cardiac contraction and relaxation, known as calcium transient, in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) would be an attractive strategy for asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b863531a331d76d11d9ffcff397d6fb4
https://doi.org/10.2131/jts.42.519
https://doi.org/10.2131/jts.42.519
Publikováno v:
The AAPS Journal. 21
Accurate prediction of human pharmacokinetics for drugs remains challenging, especially for non-cytochrome P450 (P450) substrates. Hepatocytes might be suitable for predicting hepatic intrinsic clearance (CLint) of new chemical entities, because they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af4160af0093efed7d3a36d32e08999
https://doi.org/10.1208/s12248-019-0294-1
https://doi.org/10.1208/s12248-019-0294-1
Publikováno v:
Biopharmaceuticsdrug disposition. 40(5-6)
The metabolism and pharmacokinetics of DSP-0565 [2-(2'-fluoro[1,1'-biphenyl]-2-yl)acetamide], an antiepileptic drug candidate, was investigated in rats, dogs, and humans. In human hepatocytes, [14 C]DSP-0565 was primarily metabolized via amide bond h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b54384e453c28bc97141fb964c5728
https://pubmed.ncbi.nlm.nih.gov/30924154
https://pubmed.ncbi.nlm.nih.gov/30924154
Autor:
Tadashi, Tsubouchi, Takeshi, Kunimatsu, Shinji, Tsujimoto, Akihiko, Kiyoshi, Yasunori, Katsura, Seiko, Oku, Kazuhiro, Chihara, Yukiko, Mine, Toru, Yamada, Isao, Shimizu, Kiyoko, Bando
Publikováno v:
European journal of pharmacology. 826
The pharmacological activity of DSP-6952, a novel compound was investigated, compared to that of clinically efficacious gastrointestinal (GI) prokinetic 5-hydroxytryptamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91091cee40ec448cdde13f1ae75e75c8
https://pubmed.ncbi.nlm.nih.gov/29501863
https://pubmed.ncbi.nlm.nih.gov/29501863