Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kiyokazu Jimpo"'
Autor:
Takenari Nakagome, Toshiaki Komatsu, Hisao Tobiki, Kiyokazu Jimpo, Takao Okuda, Hiroshi Noguchi, Hirotada Yamada
Publikováno v:
The Journal of antibiotics. 36(5)
The influence of various 3-substituents on the antibacterial activity of 7 beta-[D-2-(4-hydroxy-6-methylpyridine-3-carbonylamino)-2-(4-hydroxyphenyl) acetamido]ceph-3-em-4-carboxylic acids (III) was investigated. Introduction of an acidic substituent
Autor:
Toshiaki Komatsu, Hisao Tobiki, Kiyokazu Jimpo, Hirotada Yamada, Takenari Nakagome, Takeuchi Yutaka, Hiroshi Noguchi, Takao Okuda, Koushiro Gooda, Ueda Shinji, Kenji Irie
Publikováno v:
The Journal of antibiotics. 36(5)
The influence of the chirality of the 7-acyl side chain and of various N-acyl moieties (A-CO-) on the in vitro activity of 7 beta-[2-acylamino-2-(4-hydroxyphenyl)acetamido ]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acids (6) wa
Autor:
Takenari Nakagome, Hirotada Yamada, Kiyokazu Jimpo, Kenji Irie, Toshiaki Komatsu, Hiroshi Noguchi, Hisao Tobiki
Publikováno v:
The Journal of antibiotics. 36(5)
The synthesis and the antibacterial activity of 7 beta-[D-2-[(4-hydroxy-1,5-naphthyridine-3-carbonylamino)- and (4-hydroxypyridine-3-carbonylamino)]-2-(4-hydroxyphenyl)acetamido]-cephalosporins with various substituents at the 3-position in the cephe
Autor:
Ueda Shinji, Hirotada Yamada, Takenari Nakagome, Hiroyuki Suzuki, Hisao Tobiki, Kiyokazu Jimpo, Norihiko Tanno
Publikováno v:
Bulletin of the Chemical Society of Japan. 57:3333-3334
The 4-methoxybenzyloxycarbonyl group of 7-[D-2-(4-hydroxyphenyl)-2-(4-methoxybenzyloxycarbonylamino)acetamido]cephalosporanic acid was effectively removed with p-toluenesulfonic acid in acetonitrile. The mechanism of the deprotection is discussed and