Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kiyohito Taimatsu"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128319 (2015)
The type II clustered regularly interspaced short palindromic repeats (CRISPR) associated with Cas9 endonuclease (CRISPR/Cas9) has become a powerful genetic tool for understanding the function of a gene of interest. In zebrafish, the injection of Cas
Externí odkaz:
https://doaj.org/article/8c0f820320244d0abe387d16702d4bc5
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 5, p 727 (2016)
The zebrafish (Danio rerio) is an ideal vertebrate model to investigate the developmental molecular mechanism of organogenesis and regeneration. Recent innovation in genome editing technologies, such as zinc finger nucleases (ZFNs), transcription act
Externí odkaz:
https://doaj.org/article/1ae40f84f24847b4b3f86d6a074037b1
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
DEAD-box helicase 5 (Ddx5) functions as an ATP-dependent RNA helicase and as a transcriptional coactivator for several transcription factors; however, the developmental function of the ddx5 gene in vertebrates is not fully understood. We found that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31f4a83331c29cd3c32ca81da639d12
http://link.springer.com/article/10.1038/s41598-020-71143-2
http://link.springer.com/article/10.1038/s41598-020-71143-2
Autor:
Marvel, Miranda, Aniket V. Gore, Kiyohito Taimatsu, Davis, Andrew, Castranova, Daniel, Weinstein, Brant M.
Embryonic development, a process in which pluripotent cells differentiate into specific organs, is controlled by genetic and epigenetic factors. Epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and others
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8d56b55a64fd4f6cce6b8caa12dee1
Publikováno v:
Gene expression patterns : GEP. 30
Mammalian SLURP1 and SLURP2 belong to the Ly-6/uPAR superfamily and are involved in maintaining the physiological integrity of keratinocytes. However, the developmental expression and functions of other Ly-6/uPAR family genes in vertebrates are still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c968b326b9cb030c08b1a6527ffa2d4
https://pubmed.ncbi.nlm.nih.gov/30149151
https://pubmed.ncbi.nlm.nih.gov/30149151
Autor:
Rie Ohga, Kanoko Yanagi, Kiyohito Taimatsu, Takaaki Mori, Hitoshi Morita, Hiroaki Suzuki, Atsuo Kawahara
Publikováno v:
Gene expression patterns : GEP. 30
The cocaine- and amphetamine-regulated transcript (CART) genes are involved in the neural regulation of energy homeostasis; however, their developmental expressions and functions are not fully understood in vertebrates. We have identified a novel zeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f8c87c495fc8c780186504205ced27
https://pubmed.ncbi.nlm.nih.gov/30125742
https://pubmed.ncbi.nlm.nih.gov/30125742
Autor:
Rie Ohga, Junken Aoki, Satoshi Ota, Yu Hisano, Michiko Muraki, Atsuo Kawahara, Kiyohito Taimatsu, Hirohito Kotani, Asuka Inoue
Publikováno v:
Genes to Cells. 20:647-658
The lipid mediator sphingosine-1-phosphate (S1P) regulates various physiological and pathological phenomena such as angiogenesis and oncogenesis. Secreted S1P associates with the G-protein-coupled S1P receptors (S1PRs), leading to the activation of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc200dee4ff00f2185f3715f3961b75e
https://doi.org/10.1111/gtc.12259
https://doi.org/10.1111/gtc.12259
Autor:
Hirotaka Matsumoto, Junken Aoki, Yu Hisano, Asuka Inoue, Hirohito Kotani, Kiyohito Taimatsu, Rie Ohga, Michiyo Okudaira, Atsuo Kawahara
Publikováno v:
Journal of Biological Chemistry. 290:14841-14851
Sphingosine 1-phosphate (S1P) is synthesized from sphingosine by sphingosine kinases (SPHK1 and SPHK2) in invertebrates and vertebrates, whereas specific receptors for S1P (S1PRs) selectively appear in vertebrates, suggesting that S1P acquires novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7e3638b0b3571ff8d2a033e7e84449
https://doi.org/10.1074/jbc.m114.634717
https://doi.org/10.1074/jbc.m114.634717
Publikováno v:
Developmental Dynamics. 244:651-668
Background: For the delivery of oxygen, the correct size/number of erythrocytes is required for proper blood flow. Results: By combined analyses of wild-type (WT) medaka and the kyoho (kyo) mutant, we found proliferation-mediated adaptation for size/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a90112a1983c462b1a9d1cea072718
https://doi.org/10.1002/dvdy.24259
https://doi.org/10.1002/dvdy.24259
Publikováno v:
Bioengineered. 8(3)
Genome editing technologies, such as transcription activator-like effector nuclease (TALEN) and the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) systems, can induce DNA double-strand breaks (DSBs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baee129daac33c54a65e2445b96b1d6
https://pubmed.ncbi.nlm.nih.gov/28272984
https://pubmed.ncbi.nlm.nih.gov/28272984