Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Kiyohiro Imai"'
Autor:
Shigenori Nagatomo, Yukifumi Nagai, Yayoi Aki, Hiroshi Sakurai, Kiyohiro Imai, Naoki Mizusawa, Takashi Ogura, Teizo Kitagawa, Masako Nagai
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135080 (2015)
Human hemoglobin (Hb), which is an α2β2 tetramer and binds four O2 molecules, changes its O2-affinity from low to high as an increase of bound O2, that is characterized by 'cooperativity'. This property is indispensable for its function of O2 trans
Externí odkaz:
https://doaj.org/article/7ba20730c1c849c7bc01800d7575fbd0
Publikováno v:
Structure and Infrastructure Engineering. 18:1428-1441
Autor:
Dan M. Frangopol, Kiyohiro Imai
Publikováno v:
Reliability and Optimization of Structural Systems ISBN: 9780203740965
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f11946446124cc50f799f1bcb80ffcf5
https://doi.org/10.1201/9780203740965-24
https://doi.org/10.1201/9780203740965-24
Autor:
Megumi Kayanuma, Yukifumi Nagai, Mitsuo Shoji, Chika Kobayashi, Saburo Neya, Naoki Mizusawa, Shigenori Nagatomo, Hiroshi Sakurai, Masako Nagai, Kiyohiro Imai
Publikováno v:
The Journal of Physical Chemistry B. 119:1275-1287
Incorporation of the heme into globin induces a prominent circular dichroism (CD) band in the Soret region. The appearance of heme optical activity is widely believed to arise from the interaction between the heme and aromatic residues of the globin.
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 19:301-307
We substituted strongly electron-withdrawing trifluoromethyl ( CF3) group(s) as heme side chain(s) of human adult hemoglobin (Hb) to achieve large alterations of the heme electronic structure, in order to elucidate the relationship between the oxygen
Publikováno v:
Chirality. 26:438-442
While heme alone does not exhibit circular dichroism (CD) spectrum, it exhibits a prominent positive CD band in the Soret region when incorporated into apoglobin of myoglobin (Mb) and hemoglobin (Hb). The appearance of this optical activity is widely
Autor:
Kiyohiro Imai, Saburo Neya, Takashi Matsuo, Tomokazu Shibata, Takashi Ogura, Satoshi Nagao, Izumi Ishigami, Ryu Nishimura, Hulin Tai, Osami Shoji, Akihiro Suzuki, Yasuhiko Yamamoto, Shun Hirota, Yoshihito Watanabe
Publikováno v:
Inorganic Chemistry. 53:1091-1099
We analyzed the oxygen (O2) and carbon monoxide (CO) binding properties of the H64L mutant of myoglobin reconstituted with chemically modified heme cofactors possessing a heme Fe atom with a variety of electron densities, in order to elucidate the ef
Autor:
Shun Hirota, Izumi Ishigami, Ryu Nishimura, Tomokazu Shibata, Yasuhiko Yamamoto, Hulin Tai, Takashi Ogura, Kiyohiro Imai, Saburo Neya, Takashi Matsuo, Satoshi Nagao, Akihiro Suzuki
Publikováno v:
Inorganic Chemistry. 52:3349-3355
We analyzed the vibrational frequencies of the Fe-bound carbon monoxide (CO) of myoglobin reconstituted with a series of chemically modified heme cofactors possessing a heme Fe atom with a variety of electron densities. The study revealed that the st
Autor:
Naohito Hato, Masahiro Okada, Akira T. Kawaguchi, Shoichiro Takeda, Kiyohiro Imai, Jun Hyodo, Kiyofumi Gyo, Nobuhiro Hakuba
Publikováno v:
Artificial Organs. 36:178-184
To test liposome-encapsulated hemoglobin (LEH) in transient cochlear ischemia/reperfusion as a model of sudden deafness, Mongolian gerbils were randomly assigned to receive 2 mL/kg of either low-affinity LEH (l-LEH, P₅₀0₂ = 40 mm Hg), high-affi
Publikováno v:
Journal of Biological Chemistry. 284:5128-5136
Fatty acid transport protein (FATP) is an evolutionarily conserved membrane-bound protein that facilitates the uptake of extracellular long chain fatty acids. In humans and mice, six FATP isoforms have been identified and their tissue-specific distri