Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Kiyoharu Nishide"'
Autor:
Yoshiko Chihara, Kayo Ohhashi, Kiyoharu Nishide, Saori Tanida, Takashi Shigeta, Kenji Arimitsu, Hitomi Uchimoto, Miki Ikeda, Ikuo Kawasaki, Masayuki Yamashita
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 65:389-395
We synthesize optically active (R)-terbutaline 2, which is an anti-asthmatic drug, through recyclable catalytic asymmetric transfer hydrogenation (RCATH). Various chloroketones 4 were prepared and RCATH was performed on them. The products exhibit mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448ac9ff95b3390d3565175e0d4a6afb
https://doi.org/10.1248/cpb.c16-00949
https://doi.org/10.1248/cpb.c16-00949
Autor:
Hitomi Uchimoto, Asami Tarao, Kentaro Yamaguchi, Kenji Arimitsu, Kiyoharu Nishide, Ikuo Kawasaki, Aya Niki, Shinsuke Komagawa
Publikováno v:
ChemistrySelect. 1:189-194
Oxidation of organo-selenium compounds (I) with MCPBA generates bisselenoxide intermediates which undergo elimination to give products (II) with high regio- and E/Z-selectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df631b990ff64b397a997aef6ccf9be2
https://doi.org/10.1002/slct.201500054
https://doi.org/10.1002/slct.201500054
Autor:
Hitomi, Uchimoto, Miki, Ikeda, Saori, Tanida, Kayo, Ohhashi, Yoshiko, Chihara, Takashi, Shigeta, Kenji, Arimitsu, Masayuki, Yamashita, Kiyoharu, Nishide, Ikuo, Kawasaki
Publikováno v:
Chemicalpharmaceutical bulletin. 65(4)
We synthesize optically active (R)-terbutaline 2, which is an anti-asthmatic drug, through recyclable catalytic asymmetric transfer hydrogenation (RCATH). Various chloroketones 4 were prepared and RCATH was performed on them. The products exhibit mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f81776dc893d0dc64acb0a529392de9
https://pubmed.ncbi.nlm.nih.gov/28381680
https://pubmed.ncbi.nlm.nih.gov/28381680
Autor:
Kentaro Yamaguchi, Kenji Arimitsu, Asami Tarao, Aya Niki, Ikuo Kawasaki, Hitomi Uchimoto, Shinsuke Komagawa, Kiyoharu Nishide
Publikováno v:
ChemInform. 47
Oxidation of organo-selenium compounds (I) with MCPBA generates bisselenoxide intermediates which undergo elimination to give products (II) with high regio- and E/Z-selectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ef036dfa2352cb6aa5b93bc49edbf8
https://doi.org/10.1002/chin.201626208
https://doi.org/10.1002/chin.201626208
Autor:
Yukiko Akai, Takahiro Ohishi, Yoshitaka Ohishi, Kumiko Ando, Ikuo Kawasaki, Kiyoharu Nishide, Masayuki Yamashita, Yoko Sakata, Shunsaku Ohta, Azusa Ito, Yukako Tabuchi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 60:1461-1467
A series of benzo[b]furan derivatives having a five-membered heterocyclic substituent at the 2-position were prepared from 2-(1-chloro-2-formylvinyl)benzo[b]furans (2) and 2-(4-alkylcarbamoylbuta-1,3-dienyl)benzo[b]furans. These 2-heterocyclic benzo[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e78cfab441d8f186a93113f93e88fc
https://doi.org/10.1248/cpb.c12-00560
https://doi.org/10.1248/cpb.c12-00560
Autor:
Masao Koida, Ikuo Kawasaki, Yuko Ando, Takahiro Ohishi, Hidemi Kanemura, Yoshitaka Ohishi, Ryo Fukuyama, Hiromichi Nakamuta, Kiyoharu Nishide, Yukako Tabuchi, Shunsaku Ohta
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activities such as anti-osteoclastic bone resorption activity, antagonistic activity of the cysLT1 receptor and growth inhibitory activity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12436d2a413dc1f597617e01798187ff
https://doi.org/10.1016/j.bmc.2009.04.017
https://doi.org/10.1016/j.bmc.2009.04.017
Autor:
Asami Tarao, Masatoshi Kawahata, Eri Sugimoto, Ikuo Kawasaki, Kenji Arimitsu, Yukako Tabuchi, Kentaro Yamaguchi, Kiyoharu Nishide, Hiroyuki Kimura, Hitomi Uchimoto, Miki Ikeda
Publikováno v:
Organicbiomolecular chemistry. 13(21)
The oxidation of (Z)-1,2-bis(arylseleno)-1-alkenes is known to afford alkynyl selenoxides via a unique selenoxide anti-elimination mechanism; however, to date, there have been no mechanistic studies of this reaction. During our studies of this transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3609ba7c5fc8ed0d74887b26db2b0c59
https://pubmed.ncbi.nlm.nih.gov/25927266
https://pubmed.ncbi.nlm.nih.gov/25927266
Autor:
Shunsaku Ohta, Hiroyuki Yasui, Hitomi Uchimoto, Tomoko Tsuji, Kiyoharu Nishide, Kenji Arimitsu, Ikuo Kawasaki, Masayuki Yamashita
Publikováno v:
Chemicalpharmaceutical bulletin. 63(3)
Reuse of chiral ruthenium catalyst in catalytic asymmetric transfer hydrogenation (CATH) has attracted attention from economic and environmental viewpoints, and reactions using ionic liquids (ILs) as solvent are recognized as one of the most useful m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e510c1151dd05bb50acad2ab4093d3
https://pubmed.ncbi.nlm.nih.gov/25757491
https://pubmed.ncbi.nlm.nih.gov/25757491
Autor:
Takahiro Katoh, Manabu Node, Shogo Ichihashi, Chie Noguchi, Kiyoharu Nishide, Tetsuya Kajimoto, Hiroyuki Kimura, Toshio Fujiwara
Publikováno v:
Tetrahedron: Asymmetry. 17:2943-2951
Enantiomerically pure allene-1,3-dicarboxylates were easily synthesized by using epimerization–crystallization of dissymmetric allene compounds, which were prepared from acetone-1,3-dicarboxylates and naturally abundant chiral alcohols, that is, (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a4e9e70abf4b063837c351e34e447b
https://doi.org/10.1016/j.tetasy.2006.11.004
https://doi.org/10.1016/j.tetasy.2006.11.004
Autor:
Toshio Fujiwara, Hiroyuki Kimura, Takahiro Katoh, Kiyoharu Nishide, Manabu Node, Tetsuya Kajimoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 54:399-402
(-)-Epibatidine, an excellent candidate of non-opioidal anesthesia, was formally synthesized in short steps from di-(l)-menthyl (R)-allene-1,3-dicarboxylate that was facilely prepared as a single isomer by means of crystallization-induced asymmetric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa97de64d52b2ba3713e2a10d94ee9d8
https://doi.org/10.1248/cpb.54.399
https://doi.org/10.1248/cpb.54.399