Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kiyofumi Nagira"'
Autor:
Toshiyasu Sasaoka, Maine Sugiyama, Kiyofumi Nagira, Tsutomu Wada, Eriko Fujisawa, Hiroshi Tsuneki, Tetsuro Nakano, Shigeru Saito, Satoko Hori
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 298:E881-E888
Maternal insulin resistance is essential for efficient provision of glucose to the fetus. Although elevation of placental hormones is known to relate to the development of insulin resistance, the precise underlying mechanism of maternal insulin resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf070927103f143b1a3e3d25c769384
https://doi.org/10.1152/ajpendo.00649.2009
https://doi.org/10.1152/ajpendo.00649.2009
Autor:
Kazuhito Fukui, Kiyofumi Nagira, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Satoko Hori, Masashi Kobayashi, Mariko Ikubo, Shigeru Saito
Publikováno v:
Endocrinology. 147:1020-1028
We investigated the mechanisms by which estrogen alters insulin signaling in 3T3-L1 adipocytes. Treatment with 17beta-estradiol (E2) did not affect insulin-induced tyrosine phosphorylation of insulin receptor. E2 enhanced insulin-induced tyrosine pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2507d4195bbae4fb4b3498da7ffb50df
https://doi.org/10.1210/en.2005-0825
https://doi.org/10.1210/en.2005-0825
Autor:
Tsutomu Wada, Hajime Ishihara, Syota Kagawa, Kiyofumi Nagira, Mariko Ikubo, Kazuhito Fukui, Toshiyasu Sasaoka, Masashi Kobayashi
Publikováno v:
Diabetes. 54:1958-1967
We investigated the role of hepatic SH2-containing inositol 5′-phosphatase 2 (SHIP2) in glucose metabolism in mice. Adenoviral vectors encoding wild-type SHIP2 (WT-SHIP2) and a dominant-negative SHIP2 (ΔIP-SHIP2) were injected via the tail vein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b8deae6f46375807637a5a7eb62423
https://doi.org/10.2337/diabetes.54.7.1958
https://doi.org/10.2337/diabetes.54.7.1958
Autor:
Takashi Arai, Tomoko Shima, Shigeru Saito, Kiyofumi Nagira, Yasushi Kuraishi, Takao Hidaka, Masahiro Ieki, Yukiko Aono, Takafumi Nakamura
Publikováno v:
European journal of pain (London, England). 13(1)
Objectives Paclitaxel is widely used in cancer chemotherapy for the treatment of solid tumors such as breast, ovarian and lung cancer. However, it sometimes induces moderate to severe muscle pain, and impairs the patients’ quality of life. An appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692e6f84200b2d6ec6e2d74a3aed944d
https://pubmed.ncbi.nlm.nih.gov/18472288
https://pubmed.ncbi.nlm.nih.gov/18472288
Autor:
Isao Usui, Kiyofumi Nagira, Masashi Kobayashi, Toshiyasu Sasaoka, Hajime Ishihara, Shihou Murakami, Tsutomu Wada, Kazuhito Fukui
Publikováno v:
Endocrinology. 145(7)
Src homology 2-containing inositol 5′-phosphatase 2 (SHIP2) possesses 5′-phosphatase activity to specifically hydrolyze the phosphatidylinositol 3-kinase product PI(3,4,5)P3 in the regulation of insulin signaling. In the present study, we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d8a2284b091b35f6663a6ad9700c54
https://pubmed.ncbi.nlm.nih.gov/15044364
https://pubmed.ncbi.nlm.nih.gov/15044364