Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Kiyofumi, Ninomiya"'
Autor:
Yusuke Sakamoto, Naoki Inoue, Yusuke Nakanishi, Kiyofumi Ninomiya, Masayuki Yoshikawa, Osamu Muraoka, Yoshiaki Manse, Toshio Morikawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:848-855
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32c53d3f55d907a20698d7230681ffe0
https://doi.org/10.1248/bpb.b23-00167
https://doi.org/10.1248/bpb.b23-00167
Autor:
Toshio Morikawa, Fenglin Luo, Yoshiaki Manse, Hidemi Sugita, Shunsuke Saeki, Saowanee Chaipech, Yutana Pongpiriyadacha, Osamu Muraoka, Kiyofumi Ninomiya
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Geranylated coumarin constituents, kayeassamin I (1) and mammeasins E (2) and F (3) were newly isolated from the methanol extract of the flowers of Mammea siamensis (Calophyllaceae) originating in Thailand, along with five known isolates, such as mam
Externí odkaz:
https://doaj.org/article/53223d450a7040798e9070794e3ebb65
Autor:
Takafumi Saeki, Saya Yamamoto, Junji Akaki, Takahiro Tanaka, Misaki Nakasone, Hidemasa Ikeda, Wei Wang, Makoto Inoue, Yoshiaki Manse, Kiyofumi Ninomiya, Toshio Morikawa
This study aimed to compare fat accumulation in young and aged mice raised on a high-fat diet and to characterize the obesity-reducing effects of a traditional Japanese Kampo medicine, bofutsushosan (BTS; fangfengtongshengsan in Chinese). Aged mice f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec9ff272057f632ae164e3dc15c3a41
https://doi.org/10.21203/rs.3.rs-2703227/v1
https://doi.org/10.21203/rs.3.rs-2703227/v1
Autor:
Akifumi Nagatomo, Naoki Inoue, Takuya Konno, Yin Xu, Chinatsu Sakamoto, Mayuko Sone, Aya Shibasaka, Osamu Muraoka, Kiyofumi Ninomiya, Masayuki Yoshikawa, Yoshiaki Manse, Toshio Morikawa
Publikováno v:
Journal of Natural Medicines. 76:654-669
The methanol extract from the leaves of Ilex paraguariensis A. St.-Hil. (Aquifoliaceae), popularly known as mate, maté, or yerba maté, inhibits the intracellular triglyceride accumulation in HepG2 cells and suppresses the plasma triglyceride elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c64cc38120bb064a53a18118ade8b1
https://doi.org/10.1007/s11418-022-01614-5
https://doi.org/10.1007/s11418-022-01614-5
Autor:
Akifumi Nagatomo, Kiyofumi Ninomiya, Shinsuke Marumoto, Chie Sakai, Shuta Watanabe, Wakana Ishikawa, Yoshiaki Manse, Takashi Kikuchi, Takeshi Yamada, Reiko Tanaka, Osamu Muraoka, Toshio Morikawa
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13141
The seed oil of Carapa guianensis Aublet (Andiroba) has been used in folk medicine for its insect-repelling, anti-inflammatory, and anti-malarial activities. This study aimed to examine the triglyceride (TG) reducing effects of C. guianensis-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cf0f4b3decac112144d08f3bc13092
Autor:
Fenglin Luo, Masayuki Yoshikawa, Yamato Inoue, Toshio Morikawa, Osamu Muraoka, Kiyofumi Ninomiya, Haruko Fukui, Tsuyoshi Kaieda, Yoshiaki Manse
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:464-471
A methanol extract from the underground part of Calanthe discolor Lindl. (Orchidaceae) demonstrated significant proliferative activity on human hair follicle dermal papilla cells (HFDPC, % of control: 120.8 ± 0.2%) at 100 µg/mL against HFDPC. Throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50bd9178c24403ed9db73f53609255b0
https://doi.org/10.1248/cpb.c21-00006
https://doi.org/10.1248/cpb.c21-00006
Autor:
Osamu Muraoka, Masayuki Yoshikawa, Hisashi Matsuda, Kiyofumi Ninomiya, Genzoh Tanabe, Toshio Morikawa
Publikováno v:
Journal of Natural Medicines
Abstract During our studies characterizing functional substances from food resources for the prevention and treatment of lifestyle-related diseases, we isolated the active constituents, salacinol (1) and neokotalanol (4), and related thiosugar sulfon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0dfc8151cd0a2427f6a7338bee90ff
http://europepmc.org/articles/PMC8159842
http://europepmc.org/articles/PMC8159842
Autor:
Masayuki Yoshikawa, Osamu Muraoka, Kiyofumi Ninomiya, Masato Odawara, Masakazu Kobayashi, Toshio Morikawa, Junji Akaki
Publikováno v:
Journal of Medicinal Food. 24:10-17
The number of diabetes mellitus and borderline diabetes cases is increasing and poses a serious problem worldwide. Plants of the genus Salacia are known to have α-glucosidase inhibitory activity an...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117272fd0dbc118f8baa3fbbb436b7c6
https://doi.org/10.1089/jmf.2020.4751
https://doi.org/10.1089/jmf.2020.4751
Autor:
Fumihiro Ishikawa, Kiyofumi Ninomiya, Shinya Nakamura, Toshio Morikawa, Weijia Xie, Genzoh Tanabe, Yuuto Yoshimori, Aiko Hirano, Osamu Muraoka, Katsuki Takashima, Kana Nishida, Shinsuke Marumoto, Isao Nakanishi
Publikováno v:
RSC Advances. 11:3221-3225
We show that salacinol-type α-glucosidase inhibitors are ligand-compatible with the GH 31 family. Salacinol and its 3′-O-benzylated analogs inhibit human lysosomal α-glucosidase at submicromolar levels. Simple structure-activity relationship stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3372ad41be2d90c5ccedf16197910934
https://doi.org/10.1039/d0ra10038b
https://doi.org/10.1039/d0ra10038b
Autor:
Xiaoguang Jia, Yingni Pan, Kiyofumi Ninomiya, Toshio Morikawa, Hisashi Matsuda, Masayuki Yoshikawa, Seikou Nakamura, Haihui Xie, Dan Yuan, Osamu Muraoka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:675-689
An Orobanchaceae plant Cistanche tubulosa (SCHENK) WIGHT (Kanka-nikujuyou in Japanese), which is one of the authorized plant resources as Cistanches Herba in both Japanese and Chinese Pharmacopoeias, is a perennial parasitic plant growing on roots of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36d9d9041e5af1e4cba864fc0832d2f
https://doi.org/10.1248/cpb.c19-00008
https://doi.org/10.1248/cpb.c19-00008