Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kiweon Cha"'
Autor:
Young Jun An, Ye-Eun Jung, Kyeong Won Lee, Prashant Kaushal, In Young Ko, Seung Min Shin, Sangho Ji, Wookyung Yu, Cheolju Lee, Won-Kyu Lee, Kiweon Cha, Jung-Hyun Lee, Sun-Shin Cha, Hyung-Soon Yim
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0307499 (2024)
Fibroblast growth factor 2 (FGF2) is an attractive biomaterial for pharmaceuticals and functional cosmetics. To improve the thermo-stability of FGF2, we designed two mutants harboring four-point mutations: FGF2-M1 (D28E/C78L/C96I/S137P) and FGF2-M2 (
Externí odkaz:
https://doaj.org/article/40e83970943d41ca992fa7cd62a2cfcc
Autor:
Taek‐Keun Kim, Chang Sik Park, Jihye Jang, Mi Ra Kim, Hee‐Jun Na, Kangseung Lee, Hyun Jung Kim, Kyun Heo, Byong Chul Yoo, Young‐Myeong Kim, Je‐Wook Lee, Su Jin Kim, Eun Sung Kim, Dae Young Kim, Kiweon Cha, Tae Gyu Lee, Sukmook Lee
Publikováno v:
Molecular Oncology, Vol 12, Iss 3, Pp 356-372 (2018)
The C‐type lectin‐like domain of CLEC14a (CLEC14a‐C‐type lectin‐like domain [CTLD]) is a key domain that mediates endothelial cell–cell contacts in angiogenesis. However, the role of CLEC14a‐CTLD in pathological angiogenesis has not yet
Externí odkaz:
https://doaj.org/article/29cd0caafe6040fc935cb8e939eb8841
Autor:
Yun Jeong Kim, Jeong-Hee Kim, Kwang-Jun Lee, Myung-Min Choi, Yeon Hee Kim, Gi-Eun Rhie, Cheon-Kwon Yoo, Kiweon Cha, Na-Ri Shin
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120840 (2015)
Botulinum neurotoxin type A (BoNT/A) is the most potent protein toxin and causes fatal flaccid muscle paralysis by blocking neurotransmission. Application of BoNT/A has been extended to the fields of therapeutics and biodefense. Nevertheless, the glo
Externí odkaz:
https://doaj.org/article/180818c69c4f418b88a47660f7d6fd8d
Autor:
Soyoun Kim, Sang Mun Bae, Junyoung Seo, Kiweon Cha, Meilan Piao, Sun-Ji Kim, Hye-Nam Son, Rang-Woon Park, Byung-Heon Lee, In-San Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121171 (2015)
A number of peptide-based indicators have been identified and reported as potential apoptosis probes, offering great promise for early assessment of therapeutic efficacy in several types of cancer. Direct comparison of the newly developed probes with
Externí odkaz:
https://doaj.org/article/1fd3af61bf83415ab18568504e18568e
Autor:
Eunsung Jun, Soyoun Kim, Jong-Ho Kim, Kiweon Cha, In-Seop So, Hye-Nam Son, Byung-Heon Lee, Kwangmeyung Kim, Ick Chan Kwon, Sang Yoon Kim, In-San Kim
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118310 (2015)
We developed and tested a multicomponent peptide-woven siRNA nanocomplex (PwSN) comprising different peptides designed for efficient cellular targeting, endosomal escape, and release of siRNA. To enhance tumor-specific cellular uptake, we connected a
Externí odkaz:
https://doaj.org/article/96c18657b0af4b6da456ae717cf9040b
It is known that VEGF receptors (VEGFR) and integrins interact with each other to regulate angiogenesis. We reported previously that the fasciclin 1 (FAS1) domain–containing protein, TGFBIp/βig-h3 (TGF-β–induced protein) is an angiogenesis regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31d06b6a0c123110a4326cc433af1d4d
https://doi.org/10.1158/1541-7786.c.6541527
https://doi.org/10.1158/1541-7786.c.6541527
PDF file - 259K, S1 Cell cytotoxicity assay. S2 FAS1-domain protein inhibits VEGF165-induced 9 association of alphavbeta3 integrin with VEGFR-2 and VEGFR-2 phosphorylation via alphavbeta3 10 integrin. S3 FAS1-domain protein inhibits both vitronectin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a1d8cc58a0c9ef5290bd27b23ca055
https://doi.org/10.1158/1541-7786.22516884.v1
https://doi.org/10.1158/1541-7786.22516884.v1
Autor:
Young Jun An, Kyeong Won Lee, Ye-Eun Jung, Ye Eun Jeong, Su-Jin Kim, Jurang Woo, Jonghwa Jin, Won-Kyu Lee, Kiweon Cha, Sun-Shin Cha, Jung-Hyun Lee, Hyung-Soon Yim
Publikováno v:
International Journal of Peptide Research and Therapeutics. 28
Fibroblast Growth Factor 7 (FGF7), a growth factor specific to epithelial cells, has attracted attention as a therapeutic protein. However, FGF7 has a limitation in its use due to low protein stability. Here, the mutations were designed to increase t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f29005e6ffd53ce4045954c84a5bcc4
https://doi.org/10.1007/s10989-022-10394-1
https://doi.org/10.1007/s10989-022-10394-1
Autor:
Eun Sung Kim, Jihye Jang, Chang Sik Park, Young-Myeong Kim, Su Jin Kim, Taek-Keun Kim, Sukmook Lee, Kyun Heo, Byong Chul Yoo, Je-Wook Lee, Kangseung Lee, Mi Ra Kim, Kiweon Cha, Dae Young Kim, Hee-Jun Na, Hyun Jung Kim, Tae Gyu Lee
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 12, Iss 3, Pp 356-372 (2018)
Molecular Oncology, Vol 12, Iss 3, Pp 356-372 (2018)
The C-type lectin-like domain of CLEC14a (CLEC14a-C-type lectin-like domain [CTLD]) is a key domain that mediates endothelial cell-cell contacts in angiogenesis. However, the role of CLEC14a-CTLD in pathological angiogenesis has not yet been clearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95302b7985415739459d380b75484271
http://europepmc.org/articles/PMC5830631
http://europepmc.org/articles/PMC5830631
Autor:
Sun Hwa Park, Jae Min Lee, So-Young Choi, Janghyun Kim, Hong Sik Lee, Boram Lee, Ji Wook Moon, Kiweon Cha, Heekyung Park, Ji Hoon Park, Jung Eun Lee, Junseo Oh
Activated hepatic stellate cells (HSCs) play a key role in liver fibrosis and inactivating HSCs has been considered a promising therapeutic approach. We previously showed that albumin and its derivative, retinol binding protein (RBP)-albumin domain I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf26946e5953a3e6cab62d55c558bd49
https://doi.org/10.1101/753152
https://doi.org/10.1101/753152