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Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia.

Autor: Martin-Loeches I; St James's Hospital, Trinity College Dublin, James Street, Dublin 8, Ireland.; Universitat de Barcelona, IDIBAPS, CIBERes, Barcelona, Spain., Timsit JF; UMR 1137, IAME, Université Paris Diderot, F75018, Paris, France., Kollef MH; Washington University School of Medicine, 4523 Clayton Ave, Campus Box 8052, St. Louis, MO 63110, USA., Wunderink RG; Northwestern University Feinberg School of Medicine, 303 East Superior St, Simpson Querrey 5th Floor, Suite 5-301, Chicago, IL 60611, USA., Shime N; Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan., Nováček M; General Hospital of Kolin, Zizkova 146, Kolin 3, 280 00, Czech Republic., Kivistik Ü; North Estonia Medical Centre Foundation, Sütiste tee 19, Tallinn, Harjumaa 13419, Estonia., Réa-Neto Á; Universidade Federal do Paraná, Rua XV de Novembro, 1299 - Centro, Curitiba - PR, 80060-000, Brazil., Bruno CJ; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Huntington JA; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Lin G; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Jensen EH; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Motyl M; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Yu B; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Gates D; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Butterton JR; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA., Rhee EG; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.

Publikováno v: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2022 Mar 31; Vol. 77 (4), pp. 1166-1177.