Pharmacogenomics of statins: understanding susceptibility to adverse effects

Autor: Kitzmiller JP, Mikulik EB, Dauki AM, Mukherjee C, Luzum JA

Publikováno v: Pharmacogenomics and Personalized Medicine, Vol Volume 9, Pp 97-106 (2016)

Joseph P Kitzmiller,1 Eduard B Mikulik,1 Anees M Dauki,2 Chandrama Murkherjee,1 Jasmine A Luzum3 1Department of Biological Chemistry and Pharmacology, College of Medicine, 2College of Pharmacy, The Ohio State University, Columbus, OH, 3Department of

Externí odkaz: https://doaj.org/article/6261d75388784a28ae585d6a1f04ad6c

Candidate-Gene Study of Functional Polymorphisms in SLCO1B1 and CYP3A4/5 and the Cholesterol-Lowering Response to Simvastatin.

Autor: Kitzmiller, JP¹ joseph.kitzmiller@osumc.edu, Luzum, JA², Dauki, A^1,3, Krauss, RM⁴, Medina, MW⁴

Publikováno v: CTS: Clinical & Translational Science. May2017, Vol. 10 Issue 3, p172-177. 6p.

Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.

Autor: Luzum JA; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI, USA. jluzum@med.umich.edu.; Department of Biological Chemistry and Pharmacology, Ohio State University College of Medicine, Columbus, OH, USA. jluzum@med.umich.edu., English JD; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI, USA., Ahmad US; Heart and Vascular Institute, Summa Health System, Akron, OH, USA.; Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, OH, USA., Sun JW; Center for Pharmacogenomics, Ohio State University College of Medicine, Columbus, OH, USA., Canan BD; Department of Physiology and Cell Biology, Ohio State University College of Medicine, Columbus, OH, USA., Sadee W; Center for Pharmacogenomics, Ohio State University College of Medicine, Columbus, OH, USA., Kitzmiller JP; Department of Biological Chemistry and Pharmacology, Ohio State University College of Medicine, Columbus, OH, USA.; Center for Pharmacogenomics, Ohio State University College of Medicine, Columbus, OH, USA., Binkley PF; Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, OH, USA.

Publikováno v: Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2019 Aug; Vol. 12 (4), pp. 280-289. Date of Electronic Publication: 2019 Feb 12.

Clinical features related to statin-associated muscle symptoms.

Autor: Ochs-Balcom HM; Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, 270 Farber Hall, Buffalo, New York, 14214-8001, USA., Nguyen LM; Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, New York, USA., Ma C; Department of Biostatistics, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York, USA., Isackson PJ; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.; Kaleida Health Laboratories, Buffalo, New York, USA., Luzum JA; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan, USA., Kitzmiller JP; Center for Pharmacogenomics, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA., Tarnopolsky M; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada., Weisman M; Department of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, California, USA., Christopher-Stine L; Department of Medicine, Division of Rheumatology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Peltier W; Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Wortmann RL; Department of Medicine, The Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA., Vladutiu GD; Department of Pediatrics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.; Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.; Department of Pathology & Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.

Publikováno v: Muscle & nerve [Muscle Nerve] 2019 May; Vol. 59 (5), pp. 537-543. Date of Electronic Publication: 2019 Jan 11.

Clinical pharmacogenomics: patient perspectives of pharmacogenomic testing and the incidence of actionable test results in a chronic disease cohort.

Autor: Mukherjee C; Department of Biological Chemistry & Pharmacology, Ohio State University, Columbus, OH 43210, USA.; Department of Biological Chemistry & Pharmacology, Ohio State University, Columbus, OH 43210, USA., Sweet KM; Division of Human Genetics, Ohio State University, Columbus, OH 43210, USA.; Division of Human Genetics, Ohio State University, Columbus, OH 43210, USA., Luzum JA; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA., Abdel-Rasoul M; Center for Biostatistics, College of Medicine, Ohio State University, 1800 Cannon Drive Columbus, OH 43210, USA.; Center for Biostatistics, College of Medicine, Ohio State University, 1800 Cannon Drive Columbus, OH 43210, USA., Christman MF; Coriell Institute for Medical Research, Camden, NJ 08103, USA.; Coriell Institute for Medical Research, Camden, NJ 08103, USA., Kitzmiller JP; Department of Biological Chemistry & Pharmacology, Ohio State University, Columbus, OH 43210, USA.; Center for Pharmacogenomics, College of Medicine, Ohio State University, 5086 Graves Hall, 333 West 10th Avenue Columbus, OH 43210, USA.; Department of Biological Chemistry & Pharmacology, Ohio State University, Columbus, OH 43210, USA.; Center for Pharmacogenomics, College of Medicine, Ohio State University, 5086 Graves Hall, 333 West 10th Avenue Columbus, OH 43210, USA.

Publikováno v: Personalized medicine [Per Med] 2017 Sep; Vol. 14 (5), pp. 383-388. Date of Electronic Publication: 2017 Sep 01.