Výsledky vyhledávání - "Kitty Schapira"

Control of atherosclerotic plaque vulnerability: insights from transgenic mice

Autor: Mat J.A.P. Daemen, Esther Lutgens, Sylvia Heeneman, Kitty Schapira, Erik A.L. Biessen

Publikováno v: Frontiers in bioscience. 13:6289-6313

Atherosclerosis is a complex, progressive disease of the large systemic arteries. This multi-factorial disease is characterized by accumulation of lipids, cells and extracellular matrix in the vessel wall. The quest to unravel the molecular mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bdedd80b0c7691f9b236dbfc2bcbd9
https://doi.org/10.2741/3155

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Animal models to study plaque vulnerability

Autor: Mat J.A.P. Daemen, Kitty Schapira, S. Heeneman

Publikováno v: Current pharmaceutical design. 13(10):1013-1020

The need to identify and characterize vulnerable atherosclerotic lesions in humans has lead to the development of various animal models of plaque vulnerability. In this review, current concepts of the vulnerable plaque as it leads to an acute coronar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f7f1a891c997d176d2ecf6a84137f8
https://doi.org/10.2174/138161207780487575

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Gene profiling in atherosclerosis reveals a key role for small inducible cytokines: validation using a novel monocyte chemoattractant protein monoclonal antibody

Autor: Charles R. Mackay, Linda Beckers, Victor Koteliansky, Ann P Bijnens, Tony de Fougerolles, Esther Lutgens, Rachel I. M. van Haaften, Birgit C.G. Faber, Paul D. Rennert, Kitty Schapira, Chris T. Evelo, Brian M. Dolinski, Mat J.A.P. Daemen, Kitty B.J.M. Cleutjens, J. Gordon Porter, Matthew Jarpe, Sylvia Heeneman, Veronique Bailly

Publikováno v: Circulation, 111(25), 3443-3452. LIPPINCOTT WILLIAMS & WILKINS
Circulation, 111(25), 3443-3452. Lippincott Williams and Wilkins

Background—Pathological aspects of atherosclerosis are well described, but gene profiles during atherosclerotic plaque progression are largely unidentified.Methods and Results—Microarray analysis was performed on mRNA of aortic arches of ApoE−/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0603946f532115acd3560d53c00277
https://doi.org/10.1161/circulationaha.104.510073

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Genetic deletion or antibody blockade of alpha1beta1 integrin induces a stable plaque phenotype in ApoE-/- mice

Autor: Mat J.A.P. Daemen, Esther Lutgens, Victor Koteliansky, Sylvia Heeneman, Antonin de Fougerolles, Humphrey Gardner, Andrew Sprague, Anouk Roemen, Kitty Schapira

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology, 25(9), 1917-1924. Lippincott Williams and Wilkins

Objective— Adhesive interactions between cells and the extracellular matrix play an important role in inflammatory diseases like atherosclerosis. We investigated the role of the collagen-binding integrin α1β1 in atherosclerosis. Methods and Resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc0836284c83fd0e8b5a121afcbbc1e
https://doi.org/10.1161/01.atv.0000174807.90292.2f

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Anginex or endostatin treatment reduces plaque area in collar-induced atherosclerotic plaques of ApoE−/−mice

Autor: Arjan W. Griffioen, Marjo M. P. C. Donners, Sylvia Heeneman, Kitty Schapira, Mat J.A.P. Daemen, Daisy W. J. van der Schaft, Kevin H. Mayo

Publikováno v: Vascular Pharmacology. 45:e149-e150

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96abb023b870f20c5576e8cd7aebcb27
https://doi.org/10.1016/j.vph.2006.08.389

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