Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kittiya Somphol"'
Autor:
John B. Bremner, Paul A. Keller, Stephen G. Pyne, Mark J. Robertson, K. Sakthivel, Kittiya Somphol, Dean Baylis, Jonathan A. Coates, John Deadman, Dharshini Jeevarajah, David I. Rhodes
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1265-1270 (2012)
The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic group variations in the C-terminal amino acid component, is described. Moderate to good activity was seen against Gram-positive bacteria in vitro. One
Externí odkaz:
https://doaj.org/article/b73b82bb5d0c4dd09e0e350fd2b81356
Publikováno v:
Tetrahedron. 70:9601-9614
3,6-Bis-(2-indolyl)dibenzofurans 1,2, and carbazoles 3–6 underwent a range of electrophilic substitution reactions to produce formyl indoles 7–12, biindolyls 24–28 and 33–34, glyoxylamides 40–42, and amides 48.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98874e8367207f30672c6ddcb74ac7bf
https://doi.org/10.1016/j.tet.2014.11.014
https://doi.org/10.1016/j.tet.2014.11.014
Publikováno v:
Synlett. 24:1497-1500
Macrocyclic compounds containing four 3-substituted-4,6-dimethoxyindole units joined through the C2 and C7 positions, by a combination of direct links or methylene bridges, can be prepared by acid-catalyzed reactions of indole methanols and 2,7′-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa07abb737d6c7f202659c17ad2eab67
https://doi.org/10.1055/s-0033-1338868
https://doi.org/10.1055/s-0033-1338868
Publikováno v:
Synlett. 24:24-28
A new strategy of acid-catalysed reactions of indole methanols with a 3-aryl-4,6-dimethoxyindole-7-aldehyde leads to an efficient synthesis of a calix[3]indole with 2,2; 7,2; 7,7-links. A new calix[4]indole containing four indole units with 2,2; 7,2;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c15f953b6ebbda3973490710ba96532
https://doi.org/10.1055/s-0032-1317858
https://doi.org/10.1055/s-0032-1317858
Autor:
Kittiya Somphol, Jonathon A Coates, Mark J. Robertson, John B. Bremner, Paul A. Keller, Dean Baylis, John Deadman, Dharshini Jeevarajah, David Ian Rhodes, Stephen G. Pyne, Kandasamy Sakthivel
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1265-1270 (2012)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic group variations in the C-terminal amino acid component, is described. Moderate to good activity was seen against Gram-positive bacteria in vitro. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c4de2ef32ab669c39aef5c2532c431
https://doi.org/10.3762/bjoc.8.142
https://doi.org/10.3762/bjoc.8.142
Autor:
Mohan M. Bhadbhade, Naresh Kumar, Kittiya Somphol, Mardi Santoso, Christopher R. Gardner, David StC. Black
Publikováno v:
Tetrahedron. 68:1862-1868
Cyclotriveratrylenes containing one benzene ring and two indole rings linked through N1 and C2 can be prepared by acid-catalysed reactions of formaldehyde and aryl aldehydes with 1,2-di-(1-indolylmethyl)benzene compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75ac20eef247b30df7965414746b972
https://doi.org/10.1016/j.tet.2011.12.080
https://doi.org/10.1016/j.tet.2011.12.080
Autor:
Ronaldâ N. Jones, Robertâ W. Buckheit, Sujata M. Bhavnani, John Deadman, Michaelâ H. Miller, Zinka Brkic, Adel Garas, Dorothyâ M. David, Jody Morgan, Johnâ B. Bremner, Karenâ M. Watson, Davidâ I. Rhodes, Stephenâ G. Pyne, Paul G. Ambrose, Dharshini Jeevarajah, Douglasâ J. Biedenbach, Kittiya Somphol, Timothyâ P. Boyle, Mark J. Robertson, Jonathanâ A. Coates, Dean Baylis, Thomasâ R. Fritsche, Andrea McCracken, Paulâ A. Keller, Adamâ S. Howe
Publikováno v:
Angewandte Chemie. 122:547-550
[Extract] While the cationic glycopeptide vancomycin has long been regarded as the gold standard for the treatment of recalcitrant Gram-positive bacterial infection, this position has been compromised by the emergence of resistant strains. The first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3d3faa31fe4afe71021738d5a7b421
https://doi.org/10.1002/ange.200904392
https://doi.org/10.1002/ange.200904392
Publikováno v:
Tetrahedron. 65:5977-5983
Indolocyclotriveratrylenes linked through C2 and C3 can be prepared by acid-catalysed reactions of indole-2- or -3-methanols. The initial example, compound 1 has been confirmed, and an X-ray crystal structure is reported. Seven new examples of indolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b3b2becaf1d703e028c00680453164
https://doi.org/10.1016/j.tet.2009.05.092
https://doi.org/10.1016/j.tet.2009.05.092
Autor:
John Deadman, John B. Bremner, Kittiya Somphol, Paul A. Keller, Jonathan Coates, Timothy P. Boyle, Stephen G. Pyne
Publikováno v:
European Journal of Medicinal Chemistry. 44:1001-1009
An efficient synthesis of two new N -acetyl-4′-arylphenylalanines is described together with their incorporation into a number of cationic peptoid antibacterial agents, one of which had an MIC of 7.8 μg/mL against Staphylococcus aureus .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606aab2d803e1622189a96710352e627
https://doi.org/10.1016/j.ejmech.2008.07.001
https://doi.org/10.1016/j.ejmech.2008.07.001
Autor:
Dena Lyras, Stephen G. Pyne, Zinka Brkic, Isabell Kemker, Andrew J. Tague, Kittiya Somphol, David C. Schröder, Steven M. Wales, Amy McKarral King, Thomas V. Riley, John B. Bremner, Katherine A. Hammer, Paul A. Keller
Thirty two new binaphthyl-based, functionalized oxazole and thiazole peptidomimetics and over thirty five novel leucine-containing intermediate oxazoles and thiazoles were prepared in this study. This includes the first examples of the direct C-5 ary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44f5d5c3f5c789158b834da4c923efe
https://doi.org/10.1039/c5ob01638j
https://doi.org/10.1039/c5ob01638j
