Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Kitti Wing Ki Chan"'
Autor:
Bing Liang Alvin Chew, An Qi Ngoh, Wint Wint Phoo, Mei Jie Grace Weng, Ho Jun Sheng, Kitti Wing Ki Chan, Eddie Yong Jun Tan, Terri Gelbart, Chenrui Xu, Gene S. Tan, Subhash G. Vasudevan, Dahai Luo
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Zika virus (ZIKV) belongs to the Flavivirus genus of the Flaviviridae family along with the four serotypes of dengue virus (DENV1–4). The recent global outbreaks of contemporary ZIKV strains demonstrated that infection can lead to neurolog
Externí odkaz:
https://doaj.org/article/05cc657aa26a4a1490e47d3d01fdb81b
Autor:
Bing Liang Alvin Chew, AN Qi Ngoh, Wint Wint Phoo, Kitti Wing Ki Chan, Zheng Ser, Nikhil K Tulsian, Shiao See Lim, Mei Jie Grace Weng, Satoru Watanabe, Milly M Choy, Jenny Low, Eng Eong Ooi, Christiane Ruedl, Radoslaw M Sobota, Subhash G Vasudevan, Dahai Luo
Publikováno v:
eLife, Vol 12 (2024)
Severe dengue infections are characterized by endothelial dysfunction shown to be associated with the secreted nonstructural protein 1 (sNS1), making it an attractive vaccine antigen and biotherapeutic target. To uncover the biologically relevant str
Externí odkaz:
https://doaj.org/article/7d2b25b34b2d403fb3d814958e7d8555
Autor:
Kitti Wing Ki Chan, Amanda Makha Bifani, Satoru Watanabe, Milly M. Choy, Eng Eong Ooi, Subhash G. Vasudevan
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104570- (2023)
Summary: Background: The Asian lineage Zika virus (ZIKV) emerged as a public health emergency in 2016 causing severe neurological pathologies with no apparent historical correlate to the mild, disease-causing innocuous member of the mosquito-borne fl
Externí odkaz:
https://doaj.org/article/e0ba4fa07bca438c88084c5164343c21
Autor:
Satoru Watanabe, Kitti Wing Ki Chan, Nicole Wei Wen Tan, Maharah Binte Abdul Mahid, Avisha Chowdhury, Kenneth Tou En Chang, Subhash G. Vasudevan
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103930- (2022)
Summary: Background: Congenital disorders associated with prenatal vertical transmission of Zika virus (ZIKV) is well established since the 2016 outbreak in the Americas. However, despite clinical reports of similar mode of transmission for other fla
Externí odkaz:
https://doaj.org/article/59a7900ca57048709b59a5f06ade3c13
Autor:
Romina Croci, Elisabetta Bottaro, Kitti Wing Ki Chan, Satoru Watanabe, Margherita Pezzullo, Eloise Mastrangelo, Claudio Nastruzzi
Publikováno v:
International Journal of Biomaterials, Vol 2016 (2016)
RNA virus infections can lead to the onset of severe diseases such as fever with haemorrhage, multiorgan failure, and mortality. The emergence and reemergence of RNA viruses continue to pose a significant public health threat worldwide with particula
Externí odkaz:
https://doaj.org/article/68ee64354ac240f6a95558dca1353038
Autor:
Yongqian Zhao, Tingjin Sherryl Soh, Jie Zheng, Kitti Wing Ki Chan, Wint Wint Phoo, Chin Chin Lee, Moon Y F Tay, Kunchithapadam Swaminathan, Tobias C Cornvik, Siew Pheng Lim, Pei-Yong Shi, Julien Lescar, Subhash G Vasudevan, Dahai Luo
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004682 (2015)
Flavivirus RNA replication occurs within a replication complex (RC) that assembles on ER membranes and comprises both non-structural (NS) viral proteins and host cofactors. As the largest protein component within the flavivirus RC, NS5 plays key enzy
Externí odkaz:
https://doaj.org/article/09f9d10f4cb74468adf79b0cf96ece1c
Autor:
Chiara Acchioni, Marta Acchioni, Flavia Mancini, Antonello Amendola, Giulia Marsili, Valentina Tirelli, Chin Piaw Gwee, Kitti Wing-Ki Chan, Silvia Sandini, Monica Bisbocci, Mohamed Mysara, Mahmoud ElHefnawi, Massimo Sanchez, Giulietta Venturi, Maria Letizia Barreca, Giuseppe Manfroni, Alberto Bresciani, Subhash G. Vasudevan, Marco Sgarbanti
Publikováno v:
Virology. 583:1-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e66b5a9c8ef0c571364874f1d67a47
https://doi.org/10.1016/j.virol.2023.03.016
https://doi.org/10.1016/j.virol.2023.03.016
Autor:
Tommaso Felicetti, Chin Piaw Gwee, Maria Sole Burali, Kitti Wing Ki Chan, Sylvie Alonso, Maria Chiara Pismataro, Stefano Sabatini, Maria Letizia Barreca, Violetta Cecchetti, Subhash G. Vasudevan, Giuseppe Manfroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a51eb3a53d39ef40cb58fc6ff7ab03
https://hdl.handle.net/11391/1544043
https://hdl.handle.net/11391/1544043
Autor:
Sai Wang, Marie Jennifer Reolo, Ann-Marie Chacko, Min Jie Alvin Tan, Satoru Watanabe, Milly M. Choy, Carla Bianca Luena Victorio, Menchie Manuel, Subhash G. Vasudevan, Kitti Wing Ki Chan, Colin X Cheng, Joanne Ong
Publikováno v:
ACS Infectious Diseases. 7:3277-3291
Dengue virus (DENV) non-structural protein 5 (NS5) is critical for viral RNA synthesis within endoplasmic reticulum (ER)-derived replication complexes in the cytoplasm; however a proportion of NS5 is known to be localized to the nucleus of infected c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553ac147c744f61f566f368702a977c6
https://doi.org/10.1021/acsinfecdis.1c00441
https://doi.org/10.1021/acsinfecdis.1c00441
Autor:
Cynthia Sung, Yuan Wei, Satoru Watanabe, How Sung Lee, Yok Moi Khoo, Lu Fan, Abhay P S Rathore, Kitti Wing-Ki Chan, Milly M Choy, Uma S Kamaraj, October M Sessions, Pauline Aw, Paola F de Sessions, Bernett Lee, John E Connolly, Martin L Hibberd, Dhanasekaran Vijaykrishna, Limin Wijaya, Eng Eong Ooi, Jenny Guek-Hong Low, Subhash G Vasudevan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004851 (2016)
UNLABELLED:CELADEN was a randomized placebo-controlled trial of 50 patients with confirmed dengue fever to evaluate the efficacy and safety of celgosivir (A study registered at ClinicalTrials.gov, number NCT01619969). Celgosivir was given as a 400 mg
Externí odkaz:
https://doaj.org/article/70f670966543435686197209b8c5a0f4