Safety and immunogenicity of the group B streptococcus vaccine AlpN in a placebo-controlled double-blind phase 1 trial

Autor: Gonzalez-Miro, Majela, Pawlowski, Andrzej, Lehtonen, Janne, Cao, Duojia, Larsson, Sara, Darsley, Michael, Kitson, Geoff, Fischer, Per B., Johansson-Lindbom, Bengt

Publikováno v: In iScience 17 March 2023 26(3)

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A group B Streptococcusalpha-like protein subunit vaccine induces functionally active antibodies in humans targeting homotypic and heterotypic strains

Autor: Pawlowski, Andrzej, Lannergård, Jonas, Gonzalez-Miro, Majela, Cao, Duojia, Larsson, Sara, Persson, Jenny J., Kitson, Geoff, Darsley, Michael, Rom, Ane Lilleøre, Hedegaard, Morten, Fischer, Per B., Johansson-Lindbom, Bengt

Publikováno v: Cell Reports Medicine; February 2022, Vol. 3 Issue: 2

A Double-Blind, Placebo-Controlled Trial to Assess Safety and Tolerability of (Thetanix) Bacteroides thetaiotaomicron in Adolescent Crohn's Disease.

Autor: Hansen R; Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK., Sanderson IR; Blizard Institute, Queen Mary University of London, London, UK., Muhammed R; Paediatric Gastroenterology, Birmingham Children's Hospital, Birmingham, UK., Allen S; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Paediatric Gastroenterology, Alder Hey Children's Hospital, Liverpool, UK., Tzivinikos C; Paediatric Gastroenterology, Alder Hey Children's Hospital, Liverpool, UK., Henderson P; Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK.; Child Life and Health, University of Edinburgh, Edinburgh, UK., Gervais L; Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK., Jeffery IB; 4D pharma Cork Limited, University College Cork, Cork, Ireland., Mullins DP; 4D pharma Cork Limited, University College Cork, Cork, Ireland., O'Herlihy EA; 4D pharma Cork Limited, University College Cork, Cork, Ireland., Weinberg JD; 4D pharma, Leeds, UK., Kitson G; ProPharma Partners Limited, Horsham, UK., Russell RK; Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK., Wilson DC; Child Life and Health, University of Edinburgh, Edinburgh, UK.

Publikováno v: Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2020 Dec 18; Vol. 12 (1), pp. e00287. Date of Electronic Publication: 2020 Dec 18.