Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Kith Pradhan"'
Autor:
Emma Rabinovich, Kith Pradhan, Iffath Islam, Helen Tracy Davido, Radhika Gali, Peter Muscarella, Henny H. Billett
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 13, p 3712 (2024)
Background: Immune thrombocytopenia (ITP) is an acquired autoimmune disorder affecting patients of all ages and backgrounds. While current standards favor medical therapy in the frontline setting, splenectomy remains an integral part of treatment in
Externí odkaz:
https://doaj.org/article/a554bceb042f4a8d805d9ffa18fdc71d
Autor:
Miao Shi, Weiguo Han, Olivier Loudig, Chirag D. Shah, Jay B. Dobkin, Steven Keller, Ali Sadoughi, Changcheng Zhu, Robert E. Siegel, Maria Katherine Fernandez, Lizett DeLaRosa, Dhruv Patel, Aditi Desai, Taha Siddiqui, Saurabh Gombar, Yousin Suh, Tao Wang, H. Dean Hosgood, Kith Pradhan, Kenny Ye, Simon D. Spivack
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract For detecting field carcinogenesis non-invasively, early technical development and case–control testing of exhaled breath condensate microRNAs was performed. In design, human lung tissue microRNA-seq discovery was reconciled with TCGA and
Externí odkaz:
https://doaj.org/article/fc18d935e09a4dee9df8eb0ff43bb23a
Autor:
Kateryna Fedorov, Eric Feldman, Yogen Saunthararajah, Aditi Shastri, Noah Kornblum, Alejandro Sica, Nishi Shah, Marina Konopleva, Kira Gritsman, Ira Braunschweig, David Levitz, Dennis Cooper, Monica Comas, Kith Pradhan, Amit Verma, Ioannis Mantzaris, Mendel Goldfinger
Publikováno v:
HemaSphere, Vol 7, p e90768e2 (2023)
Externí odkaz:
https://doaj.org/article/9099faaac4d44be1913468864d86c9e4
Autor:
Srinivas Aluri, Aarif Ahsan, Sheida Hayati, Manuel Ugidos, Punit Shah, Kate Lizotte, Samarpana Chakraborty, Kith Pradhan, Srabani Sahu, Shahina Maqbool, Aditi Shastri, Ashok Dongre, Uwe Platzbecker, Anita Gandhi, Rajasekhar Nvs Suragani, Sadanand Vodala, Amit Verma
Publikováno v:
HemaSphere, Vol 7, p e8463948 (2023)
Externí odkaz:
https://doaj.org/article/f21798ad8f984bc889d577e75e7009de
Autor:
Astha Thakkar, Kith Pradhan, Benjamin Duva, Juan Manuel Carreno, Srabani Sahu, Victor Thiruthuvanathan, Sean Campbell, Sonia Gallego, Tushar D Bhagat, Johanna Rivera, Gaurav Choudhary, Raul Olea, Maite Sabalza, Lauren C Shapiro, Matthew Lee, Ryann Quinn, Ioannis Mantzaris, Edward Chu, Britta Will, Liise-anne Pirofski, Florian Krammer, Amit Verma, Balazs Halmos
Publikováno v:
eLife, Vol 12 (2023)
Background: Cancer patients show increased morbidity with COVID-19 and need effective immunization strategies. Many healthcare regulatory agencies recommend administering ‘booster’ doses of COVID-19 vaccines beyond the standard two-dose series, f
Externí odkaz:
https://doaj.org/article/6208af8c6b20451080ddc36e3a95392b
Autor:
Yang Zhang, Xiaoyi Chen, Huamin Wang, Shanisha Gordon-Mitchell, Srabani Sahu, Tushar D. Bhagat, Gaurav Choudhary, Srinivas Aluri, Kith Pradhan, Plabani Sahu, Milagros Carbajal, Hui Zhang, Beamon Agarwal, Aditi Shastri, Robert Martell, Daniel Starczynowski, Ulrich Steidl, Anirban Maitra, Amit Verma
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Advanced pancreatic ductal adenocarcinoma (PDAC) is usually an incurable malignancy that needs newer therapeutic targets. Interleukin-1 receptor accessory protein (IL1RAP) is an innate immune mediator that regulates activation of pro-inflamm
Externí odkaz:
https://doaj.org/article/5169c822e746461397a048bb851da686
Autor:
Emma Rabinovich, Kith Pradhan, R. Alejandro Sica, Lizamarie Bachier-Rodriguez, Ioannis Mantzaris, Noah Kornblum, Aditi Shastri, Kira Gritsman, Mendel Goldfinger, Amit Verma, Ira Braunschweig
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-4 (2021)
Abstract Anti-CD19 chimeric antigen receptor T-cell therapies have shown striking clinical activity in diffuse large B-cell lymphoma but robust biomarkers predictive of responsiveness are still needed. We treated a multi-ethnic cohort of 31 diffuse l
Externí odkaz:
https://doaj.org/article/d6a2fbb6a1074b98af04337008c866f1
Autor:
Nora E. Rahmani, Nandini Ramachandra, Srabani Sahu, Nadege Gitego, Andrea Lopez, Kith Pradhan, Tushar D. Bhagat, Shanisha Gordon-Mitchell, Bianca Rivera Pena, Mohammad Kazemi, Keshav Rao, Orsi Giricz, Shahina Bano Maqbool, Raul Olea, Yongmei Zhao, Jinghang Zhang, Hamid Dolatshad, Vickram Tittrea, Dharamveer Tatwavedi, Shalini Singh, Juseong Lee, Tianyu Sun, Ulrich Steidl, Aditi Shastri, Daichi Inoue, Omar Abdel-Wahab, Andrea Pellagatti, Evripidis Gavathiotis, Jacqueline Boultwood, Amit Verma
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 9, Pp 1-8 (2021)
Abstract The BCL2-inhibitor, Venetoclax (VEN), has shown significant anti-leukemic efficacy in combination with the DNMT-inhibitor, Azacytidine (AZA). To explore the mechanisms underlying the selective sensitivity of mutant leukemia cells to VEN and
Externí odkaz:
https://doaj.org/article/ebcdc68081b74bb08aadabec941cc80f
Autor:
Seungtai Yoon, Adriana Munoz, Boris Yamrom, Yoon-ha Lee, Peter Andrews, Steven Marks, Zihua Wang, Catherine Reeves, Lara Winterkorn, Abba M. Krieger, Andreas Buja, Kith Pradhan, Michael Ronemus, Kristin K. Baldwin, Dan Levy, Michael Wigler, Ivan Iossifov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Yoon, Munoz, et al. investigate the rate of de novo coding and non-coding variants in families with high- and low-risk for autism using whole-genome sequence data from collections of families with autism. They demonstrate that de novo intronic varian
Externí odkaz:
https://doaj.org/article/436481e0995849c1abbd8e86fd1fda39
Autor:
Gaurav S Choudhary, Andrea Pellagatti, Bogos Agianian, Molly A Smith, Tushar D Bhagat, Shanisha Gordon-Mitchell, Srabani Sahu, Sanjay Pandey, Nishi Shah, Srinivas Aluri, Ritesh Aggarwal, Sarah Aminov, Leya Schwartz, Violetta Steeples, Robert N Booher, Murali Ramachandra, Maria Samson, Milagros Carbajal, Kith Pradhan, Teresa V Bowman, Manoj M Pillai, Britta Will, Amittha Wickrema, Aditi Shastri, Robert K Bradley, Robert E Martell, Ulrich G Steidl, Evripidis Gavathiotis, Jacqueline Boultwood, Daniel T Starczynowski, Amit Verma
Publikováno v:
eLife, Vol 11 (2022)
Background: Mutations in the SF3B1 splicing factor are commonly seen in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), yet the specific oncogenic pathways activated by mis-splicing have not been fully elucidated. Inflammatory immun
Externí odkaz:
https://doaj.org/article/530c5c84de264ae68b3135c39fce561b