Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of T H 9 cells to promote allergic inflammation.

Autor: Son A; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Meylan F; Office of Science and Technology, National Institute of Arthritis, Musculoskeletal, and Skin Diseases, National Institutes of Health, Bethesda, MD, USA., Gomez-Rodriguez J; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; TCR Therapeutics, Cambridge, MA, USA., Kaul Z; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Sylvester M; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Falduto GH; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Vazquez E; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Haque T; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Kitakule MM; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; Division of Pediatric Allergy Immunology and Rheumatology, Department of Pediatrics, Columbia University Medical Center, New York, NY, USA., Wang C; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Manthiram K; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Qi CF; Pathology Core, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Cheng J; Embryonic Stem Cell and Transgenic Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Gurram RK; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhu J; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Schwartzberg P; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Milner JD; Division of Pediatric Allergy Immunology and Rheumatology, Department of Pediatrics, Columbia University Medical Center, New York, NY, USA., Frischmeyer-Guerrerio PA; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Schwartz DM; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Daniella.Schwartz@pitt.edu.; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Daniella.Schwartz@pitt.edu.

Publikováno v: Nature immunology [Nat Immunol] 2023 Jun; Vol. 24 (6), pp. 1036-1048. Date of Electronic Publication: 2023 Apr 27.

Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.

Autor: Xu Q; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Milanez-Almeida P; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Martins AJ; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Radtke AJ; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA., Hoehn KB; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Oguz C; NIAID Collaborative Bioinformatics Resource (NCBR), NIAID, NIH, Bethesda, MD, USA.; Axle Informatics, Bethesda, MD, USA., Chen J; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Liu C; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Tang J; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Grubbs G; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Stein S; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA.; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Ramelli S; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA., Kabat J; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA., Behzadpour H; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA., Karkanitsa M; Laboratory of Immuno-Engineering, National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH, Bethesda, MD, USA., Spathies J; Trans-NIH Shared Resource on Biomedical Engineering and Physical Science, NIBIB, NIH, Bethesda, MD, USA., Kalish H; Trans-NIH Shared Resource on Biomedical Engineering and Physical Science, NIBIB, NIH, Bethesda, MD, USA., Kardava L; B-cell Immunology Section, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Kirby M; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA., Cheung F; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Preite S; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Duncker PC; Cytek Biosciences, Fremont, CA, USA., Kitakule MM; Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USA., Romero N; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Preciado D; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Gitman L; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Koroleva G; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Smith G; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, MD, USA., Shaffer A; Lymphoid Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., McBain IT; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., McGuire PJ; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA., Pittaluga S; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, MD, USA., Germain RN; Center for Advanced Tissue Imaging, LISB, NIAID, NIH, Bethesda, MD, USA.; Lymphocyte Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Apps R; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA., Schwartz DM; Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USA., Sadtler K; Laboratory of Immuno-Engineering, National Institute of Biomedical Imaging and Bioengineering (NIBIB), NIH, Bethesda, MD, USA., Moir S; B-cell Immunology Section, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Chertow DS; Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center (CC), NIH, Bethesda, MD, USA.; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD, USA., Kleinstein SH; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Silver Spring, MD, USA., Tsang JS; Center for Human Immunology, NIAID, NIH, Bethesda, MD, USA.; Multiscale Systems Biology Section, LISB, NIAID, NIH, Bethesda, MD, USA., Mudd P; Division of Pediatric Otolaryngology, Children's National Hospital, Washington, DC, USA.; Division of Otolaryngology, Department of Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Schwartzberg PL; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. pams@nih.gov.; National Human Genome Research Institute (NHGRI), NIH, Bethesda, MD, USA. pams@nih.gov., Manthiram K; Cell Signaling and Immunity Section, Laboratory of Immune System Biology (LISB), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. kalpana.manthiram@nih.gov.

Publikováno v: Nature immunology [Nat Immunol] 2023 Jan; Vol. 24 (1), pp. 186-199. Date of Electronic Publication: 2022 Dec 19.

Systematic evaluation of nine monogenic autoinflammatory diseases reveals common and disease-specific correlations with allergy-associated features.

Autor: Schwartz DM; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA Daniella.Schwartz@nih.gov., Kitakule MM; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Dizon BL; NIAMS, National Institutes of Health, Bethesda, Maryland, USA., Gutierrez-Huerta C; NHLBI, National Institutes of Health, Bethesda, Maryland, USA., Blackstone SA; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Burma AM; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Son A; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Deuitch N; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Rosenzweig S; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Komarow H; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Stone DL; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Jones A; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Nehrebecky M; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Hoffmann P; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Romeo T; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., de Jesus AA; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Alehashemi S; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Garg M; Rheumatology, Rochester Regional Health System, Rochester, New York, USA., Torreggiani S; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Montealegre Sanchez GA; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Honer K; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Souto Adeva G; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Barron KS; NIAID, National Institutes of Health, Bethesda, Maryland, USA., Aksentijevich I; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Ombrello AK; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Goldbach-Mansky R; Translational Autoinflammatory Diseases Section, LCIM, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA., Kastner DL; Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, Maryland, USA., Milner JD; Division of Pediatric Allergy, Immunology and Rheumatology, Columbia University, New York, New York, USA., Frischmeyer-Guerrerio P; Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Jun; Vol. 80 (6), pp. 788-795. Date of Electronic Publication: 2021 Feb 22.

Primary Atopic Disorders: Expanding Field of Inborn Errors of Immunity.

Autor: Özçifci, Güzin¹, Arbağ, Sena Nur¹, Kendir-Demirkol, Yasemin¹, Milner, Joshua D.¹ jdm2249@cumc.columbia.edu

Publikováno v: Turkish Journal of Immunology. 2024 Suppl 1, Vol. 12, p60-70. 11p.

Asociación entre procesos autoinmunes y enfermedad cardiovascular.

Autor: Morales, Christian¹, Espinoza, Cristóbal^1,2 cristobal.espinoza@ucacue.edu.ec, Sanunga, Henry², Sánchez L., Jenny¹, Hidalgo, Kimberly¹, Chagmana, Carmen¹, Chicaiza, Ángel¹, Chicaiza, Doris¹, Goyes, Melina¹

Publikováno v: Archivos Venezolanos de Farmacología y Terapéutica. 2024, Vol. 43 Issue 1, p11-17. 7p.