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Autor:
Hironori Nakamura, Masataka Ishibashi, Michinao Mizugaki, Yoshiharu Ohyama, Takanori Hishinuma, Kitae Itoh
Publikováno v:
Prostaglandins. 49:239-246
We devised a simple and effective purification for the microdetermination of prostaglandin B1 (PGB1), a metabolite of PGE1. [18O]PGB1 was synthesized by the repeated base-catalyzed hydrolysis of methyl ester derivatives in H(2)18O, to obtain an inter