Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Kit Tilly"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The highly segmented genome of Borrelia burgdorferi, the tick-borne bacterium that causes Lyme disease, is composed of a linear chromosome and more than 20 co-existing endogenous plasmids. Many plasmid-borne genes are unique to B. burgdorfer
Externí odkaz:
https://doaj.org/article/fedb16e3dce34c76ae7b262610f4e535
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006959 (2018)
Lyme disease in humans is caused by several genospecies of the Borrelia burgdorferi sensu lato (s.l.) complex of spirochetal bacteria, including B. burgdorferi, B. afzelii and B. garinii. These bacteria exist in nature as obligate parasites in an enz
Externí odkaz:
https://doaj.org/article/0bd71946e3594e2eb41b3f7a673b3365
Autor:
Beth M. Hayes, Daniel P. Dulebohn, Amit Sarkar, Kit Tilly, Aaron Bestor, Xavier Ambroggio, Patricia A. Rosa
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
Externí odkaz:
https://doaj.org/article/5be4c789ea0548d3a927669844f28562
Autor:
Beth M. Hayes, Daniel P. Dulebohn, Amit Sarkar, Kit Tilly, Aaron Bestor, Xavier Ambroggio, Patricia A. Rosa
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT The Lyme disease spirochete Borrelia burgdorferi senses and responds to environmental cues as it transits between the tick vector and vertebrate host. Failure to properly adapt can block transmission of the spirochete and persistence in eith
Externí odkaz:
https://doaj.org/article/7d81dad04a714f57a6b5be762eda8e3b
Autor:
Philip E. Stewart, Brandon L. Jutras, William K. Arnold, Brian Stevenson, Wolfram R. Zückert, Dustin Carroll, Kit Tilly, Aaron Bestor, Christina R. Savage, Haining Zhu, Catherine A. Brissette, Patricia A. Rosa, Kathryn G. Lethbridge, Janakiram Seshu
Publikováno v:
Molecular Microbiology
When the Lyme disease spirochete, Borrelia burgdorferi, transfers from a feeding tick into a human or other vertebrate host, the bacterium produces vertebrate-specific proteins and represses factors needed for arthropod colonization. Previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9874900aec726268ca17af04443fcce
https://hdl.handle.net/10919/93234
https://hdl.handle.net/10919/93234
Autor:
Philip E. Stewart, Kit Tilly, Aaron Bestor, Christina R. Savage, Catherine A. Brissette, Yvonne Tourand, Brian Stevenson, Patricia A. Rosa, Brandon L. Jutras
Publikováno v:
Journal of Bacteriology. 200
The SpoVG protein of Borrelia burgdorferi , the Lyme disease spirochete, binds to specific sites of DNA and RNA. The bacterium regulates transcription of spoVG during the natural tick-mammal infectious cycle and in response to some changes in culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1db0924dbbbae94a9d5aa9dfaa72ce
https://doi.org/10.1128/jb.00033-18
https://doi.org/10.1128/jb.00033-18
Publikováno v:
Molecular Microbiology. 89:216-227
Borrelia burgdorferi alternates between ticks and mammals, requiring variable gene expression and protein production to adapt to these diverse niches. These adaptations include shifting among the major outer surface lipoproteins OspA, OspC, and VlsE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ed3ff369004650a78cbae8f7a4a098
https://doi.org/10.1111/mmi.12271
https://doi.org/10.1111/mmi.12271
Publikováno v:
Infection and immunity. 84(5)
Borrelia burgdorferi , a Lyme disease agent, makes different major outer surface lipoproteins at different stages of its mouse–tick infectious cycle. Outer surface protein A (OspA) coats the spirochetes from the time they enter ticks until they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4c948750a93c77d979b4d322dba20a
https://pubmed.ncbi.nlm.nih.gov/26953324
https://pubmed.ncbi.nlm.nih.gov/26953324
Publikováno v:
Infection and Immunity. 80:3501-3511
Linear plasmid lp54 is one of the most highly conserved and differentially expressed elements of the segmented genome of the Lyme disease spirochete Borrelia burgdorferi . We previously reported that deletion of a 4.1-kb region of lp54 ( bba01 to bba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf795086981390592ce07c402397184
https://doi.org/10.1128/iai.00521-12
https://doi.org/10.1128/iai.00521-12
Publikováno v:
Plasmid. 68:1-12
Borrelia burgdorferi has multiple linear and circular plasmids that are faithfully replicated and partitioned as the bacterium grows and divides. The low copy number of these replicons implies that active partitioning contributes to plasmid stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3539d1a1e36b4de461561e3cfaa60e6c
https://doi.org/10.1016/j.plasmid.2012.01.009
https://doi.org/10.1016/j.plasmid.2012.01.009