Výsledky vyhledávání

Akademický článek

RPS3a over-expressed in HBV-associated hepatocellular carcinoma enhances the HBx-induced NF-κB signaling via its novel chaperoning function.

Autor: Keo-Heun Lim, Kyun-Hwan Kim, Seong Il Choi, Eun-Sook Park, Seung Hwa Park, Kisun Ryu, Yong Kwang Park, So Young Kwon, Sung-Il Yang, Han Chu Lee, In-Kyung Sung, Baik L Seong

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e22258 (2011)

Hepatitis B virus (HBV) infection is one of the major causes of hepatocellular carcinoma (HCC) development. Hepatitis B virus X protein (HBx) is known to play a key role in the development of hepatocellular carcinoma (HCC). Several cellular proteins

Externí odkaz: https://doaj.org/article/4e3d39a50d7b4de7a69caa22411aecb0

Zobrazit plný text záznamu

Publisher Correction: Conversion of a soluble protein into a potent chaperone in vivo

Autor: Seong Il Choi, Kyun-Hwan Kim, Ahyun Son, Hotcherl Jeong, Keo Heun Lim, Kisun Ryu, Soon Bin Kwon, Baik Lin Seong

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b3f37372def97ecd9de2c235ff3d6c
https://doi.org/10.1038/s41598-019-46941-y

Zobrazit plný text záznamu

Conversion of a soluble protein into a potent chaperone in vivo

Autor: Kyun-Hwan Kim, Baik Lin Seong, Kisun Ryu, Hotcherl Jeong, Ahyun Son, Seong Il Choi, Soon Bin Kwon, Keo Heun Lim

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

Protein-folding assistance and aggregation inhibition by cellular factors are largely understood in the context of molecular chaperones. As an alternative and complementary model, we previously proposed that, in general, soluble cellular macromolecul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e90bc4b141e18c24adec308c3b6223c

Zobrazit plný text záznamu

Identification of novel inhibitors of HCV RNA-dependent RNA polymerase by pharmacophore-based virtual screening and in vitro evaluation

Autor: Kyoung Tai No, Nam Doo Kim, Baik Lin Seong, Cheol Kyu Han, Seong Il Choi, Kisun Ryu, Jeong Hyeok Yoon, Kyun-Hwan Kim

Publikováno v: Bioorganic & Medicinal Chemistry. 17:2975-2982

Hepatitis C virus (HCV) is the major etiological agent of non-A, non-B hepatitis where no effective treatment is available. The HCV NS5B with RNA-dependent RNA polymerase (RdRp) activity is a key target for the treatment of HCV infection. Here we rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2a5784de9b55b9f4ec5131c029338f
https://doi.org/10.1016/j.bmc.2009.03.024

Zobrazit plný text záznamu

RNA-mediated chaperone type for de novo protein folding

Autor: Baik Lin Seong, Seong Il Choi, Kisun Ryu

Publikováno v: RNA Biology. 6:21-24

Traditionally the principles of protein folding in vivo have been obtained largely from molecular chaperone studies. Through extensive studies on molecular chaperones, it becomes clear that most proteins can fold without their assistance in vivo, sug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580e97604f19bc09b3b6c9ace40001f0
https://doi.org/10.4161/rna.6.1.7441

Zobrazit plný text záznamu

Production and characterization of active hepatitis C virus RNA-dependent RNA polymerase

Autor: Kisun Ryu, Baik Lin Seong, Seong Yeon Yoo, Seong Il Choi, Keo Heun Lim, Mi Kyung Min, Kyun-Hwan Kim, Eun Young Lee, Hajeong Kim

Publikováno v: Protein expression and purification. 71(2)

The non-structural protein 5B (NS5B) is an essential component for the genome replication of hepatitis C virus (HCV). Thus, its activity holds the potential of being a target for therapeutic actions against HCV. The availability of large amount of fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a405899e343116c6805fa34c0d9bec6
https://pubmed.ncbi.nlm.nih.gov/20060472

Zobrazit plný text záznamu

N-terminal domains of native multidomain proteins have the potential to assist de novo folding of their downstream domains in vivo by acting as solubility enhancers

Autor: Kisun Ryu, Kyoung Sim Han, Kyun-Hwan Kim, Byung Hee Kim, Chulwoo Kim, Seong Il Choi, Baik Lin Seong

Publikováno v: Protein science : a publication of the Protein Society. 16(4)

The fusion of soluble partner to the N terminus of aggregation-prone polypeptide has been popularly used to overcome the formation of inclusion bodies in the E. coli cytosol. The chaperone-like functions of the upstream fusion partner in the artifici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf4046ed1d54f3e675a94b3cd913371
https://pubmed.ncbi.nlm.nih.gov/17384228

Zobrazit plný text záznamu

RPS3a Over-Expressed in HBV-Associated Hepatocellular Carcinoma Enhances the HBx-Induced NF-κB Signaling via Its Novel Chaperoning Function

Autor: Kisun Ryu, Seung Hwa Park, Keo Heun Lim, Baik Lin Seong, Yong Kwang Park, In Kyung Sung, Han Chu Lee, Eun Sook Park, Kyun-Hwan Kim, Seong Il Choi, Sung Il Yang, So Young Kwon

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e22258 (2011)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0415e47274f1fb44d3c4a42002394b25
https://doi.org/10.1371/journal.pone.0022258

Zobrazit plný text záznamu

Akademický článek

RPS3a Over-Expressed in HBV-Associated Hepatocellular Carcinoma Enhances the HBx-Induced NF-kB Signaling via Its Novel Chaperoning Function.

Autor: Keo-Heun Lim, Kyun-Hwan Kim, Seong Il Choi, Park, Eun-Sook, Park, Seung Hwa, Kisun Ryu, Yong Kwang Park, So Young Kwon, Sung-Il Yang, Han Chu Lee, In-Kyung Sung, Baik L. Seong

Publikováno v: PLoS ONE; 2011, Vol. 6 Issue 8, p1-17, 17p

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání