Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Kisuk Lee"'
Autor:
Sven Dorkenwald, Nicholas L Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Agnes L Bodor, Adam A Bleckert, Derrick Brittain, Nico Kemnitz, William M Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Szi-Chieh Yu, Sergiy Popovych, William Wong, Manuel Castro, Chris S Jordan, Alyssa M Wilson, Emmanouil Froudarakis, JoAnn Buchanan, Marc M Takeno, Russel Torres, Gayathri Mahalingam, Forrest Collman, Casey M Schneider-Mizell, Daniel J Bumbarger, Yang Li, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S Tolias, Nuno Macarico da Costa, R Clay Reid, H Sebastian Seung
Publikováno v:
eLife, Vol 11 (2022)
Learning from experience depends at least in part on changes in neuronal connections. We present the largest map of connectivity to date between cortical neurons of a defined type (layer 2/3 [L2/3] pyramidal cells in mouse primary visual cortex), whi
Externí odkaz:
https://doaj.org/article/27b1354692bd4be48848ffb48a230736
Autor:
Casey M Schneider-Mizell, Agnes L Bodor, Forrest Collman, Derrick Brittain, Adam Bleckert, Sven Dorkenwald, Nicholas L Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Jun Zhuang, Anirban Nandi, Brian Hu, JoAnn Buchanan, Marc M Takeno, Russel Torres, Gayathri Mahalingam, Daniel J Bumbarger, Yang Li, Thomas Chartrand, Nico Kemnitz, William M Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Sergiy Popovych, William Wong, Manuel Castro, Chris S Jordan, Emmanouil Froudarakis, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S Tolias, Costas A Anastassiou, H Sebastian Seung, R Clay Reid, Nuno Maçarico da Costa
Publikováno v:
eLife, Vol 10 (2021)
Inhibitory neurons in mammalian cortex exhibit diverse physiological, morphological, molecular, and connectivity signatures. While considerable work has measured the average connectivity of several interneuron classes, there remains a fundamental lac
Externí odkaz:
https://doaj.org/article/7183b51f322941cfadb44572b84338f8
Autor:
David Deutsch, Diego Pacheco, Lucas Encarnacion-Rivera, Talmo Pereira, Ramie Fathy, Jan Clemens, Cyrille Girardin, Adam Calhoun, Elise Ireland, Austin Burke, Sven Dorkenwald, Claire McKellar, Thomas Macrina, Ran Lu, Kisuk Lee, Nico Kemnitz, Dodam Ih, Manuel Castro, Akhilesh Halageri, Chris Jordan, William Silversmith, Jingpeng Wu, H Sebastian Seung, Mala Murthy
Publikováno v:
eLife, Vol 9 (2020)
Sustained changes in mood or action require persistent changes in neural activity, but it has been difficult to identify the neural circuit mechanisms that underlie persistent activity and contribute to long-lasting changes in behavior. Here, we show
Externí odkaz:
https://doaj.org/article/4c9d78e289da493cb4da1709d1ae0bcb
Autor:
Ellen Lesser, Anthony W. Azevedo, Jasper S. Phelps, Leila Elabbady, Andrew P. Cook, Brandon Mark, Sumiya Kuroda, Anne Sustar, Anthony J. Moussa, Chris J. Dallmann, Sweta Agrawal, Su-Yee J. Lee, Brandon G. Pratt, Kyobi Skutt-Kakari, Stephan Gerhard, Ran Lu, Nico Kemnitz, Kisuk Lee, Akhilesh Halageri, Manuel Castro, Dodam Ih, Jay Gager, Marwan Tammam, Sven Dorkenwald, Forrest C. Collman, Casey M Schneider-Mizell, Derrick Brittain, Chris S Jordan, H Sebastian Seung, Thomas Macrina, Michael H Dickinson, Wei-Chung Allen Lee, John C. Tuthill
Publikováno v:
bioRxiv
Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. Because individual muscles may be used in many different behaviors, MN activity must be flexibly coordinated by dedicated premo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b8dcbf2219dfa3d28ae1a26226c892
https://europepmc.org/articles/PMC10312524/
https://europepmc.org/articles/PMC10312524/
Autor:
Runzhe Yang, Ashwin Vishwanathan, Jingpeng Wu, Nico Kemnitz, Dodam Ih, Nicholas Turner, Kisuk Lee, Ignacio Tartavull, William M. Silversmith, Chris S. Jordan, Celia David, Doug Bland, Amy Sterling, Mark S. Goldman, Emre R.F. Aksay, H. Sebastian Seung
Publikováno v:
Current Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d97ae1d5aa237abb8e6ea0dc774571f
https://doi.org/10.1016/j.cub.2023.05.010
https://doi.org/10.1016/j.cub.2023.05.010
Autor:
Brendan Celii, Stelios Papadopoulos, Zhuokun Ding, Paul G. Fahey, Eric Wang, Christos Papadopoulos, Alexander B. Kunin, Saumil Patel, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Szi-chieh Yu, Wenjing Yin, Daniel Xenes, Lindsey M. Kitchell, Patricia K. Rivlin, Victoria A. Rose, Caitlyn A. Bishop, Brock Wester, Emmanouil Froudarakis, Edgar Y. Walker, Fabian Sinz, H. Sebastian Seung, Forrest Collman, Nuno Maçarico da Costa, R. Clay Reid, Xaq Pitkow, Andreas S. Tolias, Jacob Reimer
We are now in the era of millimeter-scale electron microscopy (EM) volumes collected at nanometer resolution (Shapson-Coe et al., 2021; Consortium et al., 2021). Dense reconstruction of cellular compartments in these EM volumes has been enabled by re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21e2f4dd35616cabd72c4d26678fa28
https://doi.org/10.1101/2023.03.14.532674
https://doi.org/10.1101/2023.03.14.532674
Autor:
Zhuokun Ding, Paul G. Fahey, Stelios Papadopoulos, Eric Y. Wang, Brendan Celii, Christos Papadopoulos, Alexander B. Kunin, Andersen Chang, Jiakun Fu, Zhiwei Ding, Saumil Patel, Kayla Ponder, Taliah Muhammad, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, Emmanouil Froudarakis, Fabian Sinz, H. Sebastian Seung, Forrest Collman, Nuno Maçarico da Costa, R. Clay Reid, Edgar Y. Walker, Xaq Pitkow, Jacob Reimer, Andreas S. Tolias
Publikováno v:
bioRxiv
To understand how the neocortex underlies our ability to perceive, think, and act, it is important to study the relationship between circuit connectivity and function. Previous research has shown that excitatory neurons in layer 2/3 of the primary vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f49ecf14e08fe0585dc044ffb41c11
https://europepmc.org/articles/PMC10054929/
https://europepmc.org/articles/PMC10054929/
Autor:
Sven Dorkenwald, Claire E. McKellar, Thomas Macrina, Nico Kemnitz, Kisuk Lee, Ran Lu, Jingpeng Wu, Sergiy Popovych, Eric Mitchell, Barak Nehoran, Zhen Jia, J. Alexander Bae, Shang Mu, Dodam Ih, Manuel Castro, Oluwaseun Ogedengbe, Akhilesh Halageri, Kai Kuehner, Amy R. Sterling, Zoe Ashwood, Jonathan Zung, Derrick Brittain, Forrest Collman, Casey Schneider-Mizell, Chris Jordan, William Silversmith, Christa Baker, David Deutsch, Lucas Encarnacion-Rivera, Sandeep Kumar, Austin Burke, Doug Bland, Jay Gager, James Hebditch, Selden Koolman, Merlin Moore, Sarah Morejohn, Ben Silverman, Kyle Willie, Ryan Willie, Szi-chieh Yu, Mala Murthy, H. Sebastian Seung
Publikováno v:
Nature Methods. 19:119-128
Due to advances in automated image acquisition and analysis, whole-brain connectomes with 100,000 or more neurons are on the horizon. Proofreading of whole-brain automated reconstructions will require many person-years of effort, due to the huge volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43698ac1ef46f615475049b71530803
https://doi.org/10.1038/s41592-021-01330-0
https://doi.org/10.1038/s41592-021-01330-0
Autor:
Marissa A. Weis, Stelios Papadopoulos, Laura Hansel, Timo Lüddecke, Brendan Celii, Paul G. Fahey, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Forrest Collman, Nuno Maçarico da Costa, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, R. Clay Reid, Casey M. Schneider-Mizell, H. Sebastian Seung, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, Jacob Reimer, Andreas S. Tolias, Alexander S. Ecker
Neurons in the neocortex exhibit astonishing morphological diversity which is critical for properly wiring neural circuits and giving neurons their functional properties. The extent to which the morphological diversity of excitatory neurons forms a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86365cd9ecb9a14800b6686d516cd357
https://doi.org/10.1101/2022.12.22.521541
https://doi.org/10.1101/2022.12.22.521541
Autor:
Anthony Azevedo, Ellen Lesser, Brandon Mark, Jasper Phelps, Leila Elabbady, Sumiya Kuroda, Anne Sustar, Anthony Moussa, Avinash Kandelwal, Chris J. Dallmann, Sweta Agrawal, Su-Yee J. Lee, Brandon Pratt, Andrew Cook, Kyobi Skutt-Kakaria, Stephan Gerhard, Ran Lu, Nico Kemnitz, Kisuk Lee, Akhilesh Halageri, Manuel Castro, Dodam Ih, Jay Gager, Marwan Tammam, Sven Dorkenwald, Forrest Collman, Casey Schneider-Mizell, Derrick Brittain, Chris S. Jordan, Michael Dickinson, Alexandra Pacureanu, H. Sebastian Seung, Thomas Macrina, Wei-Chung Allen Lee, John C. Tuthill
Like the vertebrate spinal cord, the insect ventral nerve cord (VNC) mediates limb sensation and motor control. Here, we applied automated tools for electron microscopy (EM) volume alignment, neuron reconstruction, and synapse prediction to create a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c454ec276f05ed252038260ff5843645
https://doi.org/10.1101/2022.12.15.520299
https://doi.org/10.1101/2022.12.15.520299